Abstract: The various embodiments described herein include methods, devices, and systems for sanitizing a vehicle. In one aspect, a sanitizing system includes a sanitizing system housing configured to be disposed within a compartment of the vehicle, an air filtration assembly, and an ultraviolet lighting assembly. The air filtration assembly includes an air inlet and an air outlet in fluid communication with the compartment of the vehicle, an air filter, and a blower fan. The ultraviolet lighting assembly includes a UV light source, and a reflector disposed between the UV light source and the sanitizing system housing. The reflector is configured to direct UV light from the UV light source into the compartment of the vehicle.