Patents by Inventor Ross S. Johnson
Ross S. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124582Abstract: The present invention is directed to the anti-LAG-3 antibodies, LAG-3 mAb 1, LAG-3 mAb 2, LAG-3 mAb 4, LAG-3 mAb 5, and LAG-3 mAb 6, and to humanized and chimeric versions of such antibodies. The invention additionally pertains to LAG-3-binding molecules that comprise LAG-3 binding fragments of such anti-LAG-3 antibodies, immunocongugates, and to bispecific molecules, including diabodies, BiTEs, bispecific antibodies, etc., that comprise (i) such LAG-3-binding fragments, and (ii) a domain capable of binding an epitope of a molecule involved in regulating an immune check point present on the surface of an immune cells. The present invention also pertains to methods of detecting LAG-3, as well as methods of using molecules that bind LAG-3 for stimulating immune responses.Type: ApplicationFiled: November 21, 2023Publication date: April 18, 2024Inventors: Ross LA MOTTE-MOHS, Kalpana SHAH, Douglas H. SMITH, Leslie S. JOHNSON, Paul A. MOORE, Ezio BONVINI, Scott KOENIG
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Publication number: 20240084015Abstract: The present invention is directed to bispecific molecules (e.g., diabodies, bispecific antibodies, trivalent binding molecules, etc.) that possess at least one epitope-binding site that is immunospecific for an epitope of PD-1 and at least one epitope-binding site that is immunospecific for an epitope of CTLA-4 (i.e., a “PD-1×CTLA-4 bispecific molecule”). The PD-1×CTLA-4 bispecific molecules of the present invention are capable of simultaneously binding to PD-1 and to CTLA-4, particularly as such molecules are arrayed on the surfaces of human cells. The invention is directed to pharmaceutical compositions that contain such PD-1×CTLA-4 bispecific molecules, and to methods involving the use of such bispecific molecules in the treatment of cancer and other diseases and conditions. The present invention also pertains to methods of using such PD-1×CTLA-4 bispecific molecules to stimulate an immune response.Type: ApplicationFiled: November 1, 2023Publication date: March 14, 2024Inventors: Leslie S. JOHNSON, Gurunadh Reddy CHICHILI, Kalpana SHAH, Ross LA MOTTE-MOHS, Paul A. MOORE, Ezio BONVINI, Scott KOENIG
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Publication number: 20240076477Abstract: The disclosure generally relates to poly alpha-1,3-glucan compositions and articles containing them. In particular interest is comprising poly alpha-1,3-glucan ester derivatives. The poly alpha-1,3-glucan derivatives are useful in thermoprocesses and in particular, injection molding processes.Type: ApplicationFiled: August 1, 2023Publication date: March 7, 2024Inventors: ALICIA C. BRIEGEL, ROSS S. JOHNSON, VINDHYA MISHRA, KATHLEEN OPPER, SHALINI SAXENA
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Patent number: 11805893Abstract: A reconfigurable work station includes a work surface supported atop a pedestal and base. A linkage arm is affixed to the base or pedestal at a first end and pivotally connected to a fixed member at a second end. The work station can pivot, with the linkage arm, about the fixed member to be selectively positioned in multiple positions. The pedestal may be height adjustable and the work surface may be rotatable atop the pedestal. Alternatively, the work station can include two pedestals and the linkage arm can be rotatably connected to one of the pedestals to rotate the work station, as well as to pivot the work station about the fixed member. A work space includes the work station and at least one wall panel, and a work space system includes multiple work spaces. Work stations within respective work spaces can be selectively positioned in focused or collaborative configurations.Type: GrantFiled: June 22, 2022Date of Patent: November 7, 2023Assignee: Haworth, Inc.Inventors: Ralph E. Reddig, Jeffrey J. Reuschel, Ross S. Johnson, Shawn Yu, Bryan Gingrich
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Patent number: 11732110Abstract: The disclosure generally relates to poly alpha-1,3-glucan compositions and articles containing them. In particular interest is comprising poly alpha-1,3-glucan ester derivatives. The poly alpha-1,3-glucan derivatives are useful in thermoprocesses and in particular, injection molding processes.Type: GrantFiled: June 10, 2020Date of Patent: August 22, 2023Assignee: NUTRITION & BIOSCIENCES USA 4, INC.Inventors: Alicia C. Briegel, Ross S. Johnson, Vindhya Mishra, Kathleen Opper, Shalini Saxena
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Publication number: 20230192905Abstract: The disclosure generally relates to poly_alpha-1,3-glucan compositions and articles containing them. In particular interest are compositions comprising poly_alpha-1,3-glucan ester derivatives. The poly_alpha-1,3-glucan derivatives are useful in thermoprocesses and in particular, injection molding processes.Type: ApplicationFiled: November 20, 2017Publication date: June 22, 2023Inventors: Alicia C. Briegel, Ross S. Johnson, Vindhya Mishra, Kathleen Opper, Shasax Saxena
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Publication number: 20230082265Abstract: In a first aspect, an article includes an inorganic substrate and a polymer film layer. The inorganic substrate includes a material including a ceramic, a glass, a glass-ceramic or a mixture thereof. The material includes a metal cation selected from the group consisting of silicon, aluminum, titanium, zirconium, tantalum, niobium and mixtures thereof and oxygen. The polymer film layer includes a polymer including an imide group. From an interface where the inorganic substrate contacts the polymer film layer, a line-profile of a CNO— signal from negative secondary ion mass spectroscopy decreases as it moves away from the interface and into the bulk of the polymer film layer.Type: ApplicationFiled: September 6, 2022Publication date: March 16, 2023Inventors: Kostantinos Kourtakis, Benjamin Samson, Kenneth Hernandez, Ross S Johnson, Dennis Walls, Neng Xiao, Lei Zhang, Joseph Casey Johnson
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Publication number: 20220312956Abstract: A reconfigurable work station includes a work surface supported atop a pedestal and base. A linkage arm is affixed to the base or pedestal at a first end and pivotally connected to a fixed member at a second end. The work station can pivot, with the linkage arm, about the fixed member to be selectively positioned in multiple positions. The pedestal may be height adjustable and the work surface may be rotatable atop the pedestal. Alternatively, the work station can include two pedestals and the linkage arm can be rotatably connected to one of the pedestals to rotate the work station, as well as to pivot the work station about the fixed member. A work space includes the work station and at least one wall panel, and a work space system includes multiple work spaces. Work stations within respective work spaces can be selectively positioned in focused or collaborative configurations.Type: ApplicationFiled: June 22, 2022Publication date: October 6, 2022Inventors: Ralph E. Reddig, Jeffrey J. Reuschel, Ross S. Johnson, Shawn Yu, Bryan Gingrich
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Publication number: 20220267932Abstract: A process is disclosed herein comprising the steps: a) contacting an esterifying agent and a polysaccharide in the presence of a first solvent and suitable reaction conditions for a reaction time sufficient to form a product comprising a polysaccharide ester composition, the polysaccharide ester composition comprising a polysaccharide ester having a degree of substitution of about 0.001 to about 3; wherein the esterifying agent comprises an acyl halide, a phosphoryl halide, a carboxylic acid anhydride, a haloformic acid ester, a carbonic acid ester, or a vinyl ester; and the ratio of esterifying agent to polysaccharide is in the range of about 0.001:1 to about 3:1 on a molar equivalent basis; b) combining the product obtained in step a) with polyacrylonitrile; and c) spinning fibers.Type: ApplicationFiled: February 11, 2022Publication date: August 25, 2022Inventors: DOUGLAS J. ADELMAN, NATNAEL BEHABTU, ALICIA C. BRIEGEL, ROSS S. JOHNSON, CHRISTIAN PETER LENGES, KATHLEEN OPPER, ANDREAS JORGEN WEGO, CHRISTIAN HERBERT
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Patent number: 11395543Abstract: A reconfigurable work station includes a work surface supported atop a pedestal and base. A linkage arm is affixed to the base or pedestal at a first end and pivotally connected to a fixed member at a second end. The work station can pivot, with the linkage arm, about the fixed member to be selectively positioned in multiple positions. The pedestal may be height adjustable and the work surface may be rotatable atop the pedestal. Alternatively, the work station can include two pedestals and the linkage arm can be rotatably connected to one of the pedestals to rotate the work station, as well as to pivot the work station about the fixed member. A work space includes the work station and at least one wall panel, and a work space system includes multiple work spaces. Work stations within respective work spaces can be selectively positioned in focused or collaborative configurations.Type: GrantFiled: December 8, 2020Date of Patent: July 26, 2022Assignee: Haworth, Inc.Inventors: Ralph E. Reddig, Jeffrey J. Reuschel, Ross S. Johnson, Shawn Yu, Bryan Gingrich
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Publication number: 20220175130Abstract: A reconfigurable work station includes a work surface supported atop a pedestal and base. A linkage arm is affixed to the base or pedestal at a first end and pivotally connected to a fixed member at a second end. The work station can pivot, with the linkage arm, about the fixed member to be selectively positioned in multiple positions. The pedestal may be height adjustable and the work surface may be rotatable atop the pedestal. Alternatively, the work station can include two pedestals and the linkage arm can be rotatably connected to one of the pedestals to rotate the work station, as well as to pivot the work station about the fixed member. A work space includes the work station and at least one wall panel, and a work space system includes multiple work spaces. Work stations within respective work spaces can be selectively positioned in focused or collaborative configurations.Type: ApplicationFiled: December 8, 2020Publication date: June 9, 2022Inventors: Ralph E. Reddig, Jeffrey J. Reuschel, Ross S. Johnson, Shawn Yu, Bryan Gingrich
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Publication number: 20220106451Abstract: In a first aspect, a consolidated polymer film includes a first polymer layer having a first elastic modulus, wherein the first polymer layer comprises a non-melt-processible polymer comprising a polyimide, a poly(amide-imide), a block copolymer of a polyimide or a poly(amide-imide) or a mixture thereof, and a second polymer layer having a second elastic modulus, wherein the second polymer layer comprises a polyimide, a poly(amide-imide), a block copolymer of a polyimide or a poly(amide-imide) or a mixture thereof. A minor surface of the first polymer layer is in contact with a minor surface of the second polymer layer. The first elastic modulus is different from the second elastic modulus. The first and second polymer layers are bonded by consolidation.Type: ApplicationFiled: October 4, 2021Publication date: April 7, 2022Inventors: Leopoldo Alejandro Carbajal, Mark Allan Lamontia, Ross S. Johnson, Kostantinos Kourtakis, Aref Samadidooki, Mobin Yahyazadehfar, Heidi Elizabeth Burch
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Patent number: 11254094Abstract: In a first aspect, a multilayer polymer film includes a first polymer layer having a first elastic modulus and a second polymer layer having a second elastic modulus. The first polymer layer includes a polyimide, a polyamide imide, a block copolymer of a polyimide or a polyamide imide or a mixture thereof. The second polymer layer includes a polyimide, a polyamide imide, a block copolymer of a polyimide or a polyamide imide or a mixture thereof. The first elastic modulus is different from the second elastic modulus. The first and second polymer layers are bonded by consolidation. In a second aspect, a cover window for a display includes a hard coat layer and the multilayer polymer film of the first aspect. The first polymer layer of the multilayer polymer film is the layer farthest from the display and is adhered to the hard coat layer.Type: GrantFiled: October 26, 2020Date of Patent: February 22, 2022Assignee: DUPONT ELECTRONICS, INC.Inventors: Kostantinos Kourtakis, Gene M Rossi, Leopoldo Alejandro Carbajal, Mark Allan Lamontia, Mobin Yahyazadehfar, Ross S Johnson, Weiying Gao, Aref Samadidooki
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Patent number: 11248314Abstract: A process is disclosed herein comprising the steps: a) contacting an esterifying agent and a polysaccharide in the presence of a first solvent and suitable reaction conditions for a reaction time sufficient to form a product comprising a polysaccharide ester composition, the polysaccharide ester composition comprising a polysaccharide ester having a degree of substitution of about 0.001 to about 3; wherein the esterifying agent comprises an acyl halide, a phosphoryl halide, a carboxylic acid anhydride, a haloformic acid ester, a carbonic acid ester, or a vinyl ester; and the ratio of esterifying agent to polysaccharide is in the range of about 0.001:1 to about 3:1 on a molar equivalent basis; b) combining the product obtained in step a) with polyacrylonitrile; and c) spinning fibers.Type: GrantFiled: November 20, 2017Date of Patent: February 15, 2022Assignee: NUTRITION & BIOSCIENCES USA 4, INC.Inventors: Douglas J. Adelman, Natnael Behabtu, Alicia C. Briegel, Ross S. Johnson, Christian Peter Lenges, Kathleen Opper, Andreas Jürgen Wego, Christian Herbert
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Publication number: 20210053314Abstract: In a first aspect, a multilayer polymer film includes a first polymer layer having a first elastic modulus and a second polymer layer having a second elastic modulus. The first polymer layer includes a polyimide, a polyamide imide, a block copolymer of a polyimide or a polyamide imide or a mixture thereof. The second polymer layer includes a polyimide, a polyamide imide, a block copolymer of a polyimide or a polyamide imide or a mixture thereof. The first elastic modulus is different from the second elastic modulus. The first and second polymer layers are bonded by consolidation. In a second aspect, a cover window for a display includes a hard coat layer and the multilayer polymer film of the first aspect. The first polymer layer of the multilayer polymer film is the layer farthest from the display and is adhered to the hard coat layer.Type: ApplicationFiled: October 26, 2020Publication date: February 25, 2021Inventors: Kostantinos Kourtakis, Gene M Rossi, Leopoldo Alejandro Carbajal, Mark Allan Lamontia, Mobin Yahyazadehfar, Ross S Johnson, Weiying Gao, Aref Samadidooki
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Publication number: 20200399464Abstract: A polyester composition comprising at least one polyester selected from the group consisting of poly(trimethylene terephthalate), polyethylene terephthalate, polybutylene terephthalate, and copolymers thereof; and at least one poly alpha-1,3-glucan ester having a degree of substitution of from about 0.3 to 3 moles of at least one acyl group per repeat unit of poly alpha-1,3-glucan. Articles prepared from these polyester compositions exhibit at least one improved physical property such as heat deflection temperature, tensile strength, Young's modulus, or impact strength. Such polyester compositions may also be prepared from renewable resources.Type: ApplicationFiled: February 7, 2019Publication date: December 24, 2020Inventors: Ross S. Johnson, Vindhya Mishra
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Publication number: 20200308371Abstract: The disclosure generally relates to poly alpha-1,3-glucan compositions and articles containing them. In particular interest is comprising poly alpha-1,3-glucan ester derivatives. The poly alpha-1,3-glucan derivatives are useful in thermoprocesses and in particular, injection molding processes.Type: ApplicationFiled: June 10, 2020Publication date: October 1, 2020Inventors: Alicia C. Briegel, Ross S. Johnson, Vindhya Mishra, Kathleen Opper, Shalini Saxena
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Publication number: 20190345267Abstract: A process is disclosed herein comprising the step of contacting an esterifying agent and a polysaccharide in the presence of a solvent and suitable reaction conditions for a reaction time sufficient to form a product comprising a polysaccharide ester composition, wherein the polysaccharide ester composition comprises a polysaccharide ester having a degree of substitution of about 0.001 to about 3; wherein the esterifying agent comprises an acyl halide, a phosphoryl halide, a carboxylic acid anhydride, a haloformic acid ester, a carbonic acid ester, or a vinyl ester; and the ratio of esterifying agent to polysaccharide is in the range of about 0.001:1 to about 3:1 on a molar equivalent basis. In one embodiment, the polysaccharide comprises poly alpha-1,3-glucan.Type: ApplicationFiled: November 20, 2017Publication date: November 14, 2019Inventors: Douglas J. Adelman, Natnael Behabtu, Alicia C. Briegel, Ross S. Johnson, Christian Peter Lenges, Kathleen Opper
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Publication number: 20190345642Abstract: A process is disclosed herein comprising the steps: a) contacting an esterifying agent and a polysaccharide in the presence of a first solvent and suitable reaction conditions for a reaction time sufficient to form a product comprising a polysaccharide ester composition, the polysaccharide ester composition comprising a polysaccharide ester having a degree of substitution of about 0.001 to about 3; wherein the esterifying agent comprises an acyl halide, a phosphoryl halide, a carboxylic acid anhydride, a haloformic acid ester, a carbonic acid ester, or a vinyl ester; and the ratio of esterifying agent to polysaccharide is in the range of about 0.001:1 to about 3:1 on a molar equivalent basis; b) combining the product obtained in step a) with polyacrylonitrile; and c) spinning fibers.Type: ApplicationFiled: November 20, 2017Publication date: November 14, 2019Inventors: Douglas J. Adelman, Natnael Behabtu, Alicia C. Briegel, Ross S. Johnson, Christian Peter Lenges, Kathleen Opper, Andreas Jürgen Wego, Christian Herbert
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Publication number: 20180230241Abstract: The disclosure relates to benzyl ?-(1?3)-glucan, compositions comprising benzyl ?-(1?3)-glucan, and blends comprising benzyl ?-(1?3)-glucan and one or more polymers. Also disclosed are fibers comprising benzyl ?-(1?3)-glucan, and articles comprising such fibers, including articles such as a carpet, a textile, a fabric, yarn, or apparel.Type: ApplicationFiled: August 29, 2016Publication date: August 16, 2018Inventors: Ross S. Johnson, Natnael Behabtu, Alicia C. Briegel, Hugh P. McAdams, III