Patents by Inventor Ross Stein

Ross Stein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Inhibiting Tumor Growth
    Publication number: 20120208204
    Abstract: The invention provides methods and compositions for inhibiting p53-inactivated cancers. Cancer cells are preferentially inhibited compared to normal cells by inhibiting tumor survival kinases that are required for growth of tumor cells but not normal cells.
    Type: Application
    Filed: June 3, 2010
    Publication date: August 16, 2012
    Applicants: The Brigham and Women's Hospital, Inc., Peresident and Fellows of Harvard College
    Inventors: Amy Baldwin, Dorre Grueneberg, Ed Harlow, Jun Xian, Karl Munger, Karin Hellner, Marcie Glicksman, Ross Stein, Gregory Cuny
  • BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES
    Publication number: 20110306560
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Application
    Filed: August 19, 2011
    Publication date: December 15, 2011
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Tung Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES
    Publication number: 20090247731
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Application
    Filed: April 1, 2009
    Publication date: October 1, 2009
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Julian ADAMS, Yu-Ting MA, Ross STEIN, Matthew BAEVSKY, Louis GRENIER, Louis PLAMONDON
  • Boronic ester and acid compounds, synthesis and uses
    Publication number: 20070282100
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Application
    Filed: December 20, 2006
    Publication date: December 6, 2007
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Tissue transglutaminase inhibitors
    Publication number: 20060183759
    Abstract: The present invention provides novel compounds and methods useful for treating transglutaminase associated disorders such as celiac spru, Alzheimer's disease and Huntington's disease. Certain compounds of the invention are tissue transglutaminase inhibitors that comprise thiophene moieties. Methods of the invention include treatment of transglutaminase associated disorders with inhibitors of transglutaminase.
    Type: Application
    Filed: December 5, 2005
    Publication date: August 17, 2006
    Inventors: Ross Stein, April Case, Li-An Yeh, Gregory Cuny, Eric Duval
  • Boronic ester and acid compounds, synthesis and uses
    Publication number: 20060122390
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Application
    Filed: October 17, 2005
    Publication date: June 8, 2006
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Publication number: 20040167332
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Application
    Filed: December 8, 2003
    Publication date: August 26, 2004
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Patent number: 6747150
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: June 8, 2004
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Publication number: 20030199561
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Application
    Filed: March 19, 2003
    Publication date: October 23, 2003
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compositions
    Patent number: 6617317
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: September 9, 2003
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Patent number: 6548668
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: April 15, 2003
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic Ester and acid compounds, synthesis and uses
    Publication number: 20020173488
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Application
    Filed: March 18, 2002
    Publication date: November 21, 2002
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Patent number: 6465433
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: October 15, 2002
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Patent number: 6297217
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: January 25, 2000
    Date of Patent: October 2, 2001
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Patent number: 6083903
    Abstract: Disclosed herein are boronic ester and acid compounds, their synthesis and uses. More specifically, disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: July 4, 2000
    Assignee: LeukoSite, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds, synthesis and uses
    Patent number: 6066730
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: May 23, 2000
    Assignee: ProScript, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Boronic ester and acid compounds
    Patent number: 5780454
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Grant
    Filed: October 27, 1995
    Date of Patent: July 14, 1998
    Assignee: ProScript, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon