Patents by Inventor Rossitza Alargova

Rossitza Alargova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid forms of 1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzo[d]imidazol-2-yl)urea
    Patent number: 8217172
    Abstract: Solid forms of crystalline1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzo[d]imidazol-2-yl)urea, compositions containing solid forms of crystalline1 -ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzo[d]imidazol-2-yl)urea and methods of using the same are described.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: July 10, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Rossitza Alargova, Irina Kadiyala, Arnaud Le Tiran, Dainius Macikenas, Yeugang Zhang
  • SOLID FORMS OF 1-ethyl-3-(5-(5-FLUOROPYRIDIN-3-YL)-7-(PYRIMIDIN-2-YL)-1H-BENZO[D]IMIDAZOL-2-YL)UREA
    Publication number: 20100063284
    Abstract: Solid forms of crystalline1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzo[d]imidazol-2-yl)urea, compositions containing solid forms of crystalline1-ethyl-3-(5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzo[d]imidazol-2-yl)urea and methods of using the same are described.
    Type: Application
    Filed: December 5, 2008
    Publication date: March 11, 2010
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Rossitza Alargova, Irina Kadiyala, Arnaud Le Tiran, Dainius Macikenas, Yuegang Zhang
  • Process for preparing microrods using liquid-liquid dispersion
    Publication number: 20060063882
    Abstract: The invention provides a method for forming polymer microrods, the method including the steps of providing a polymer solution comprising a polymer dissolved in a first solvent; providing a dispersion medium comprising a second solvent, wherein the first solvent and the second solvent are miscible or partially soluble in each other, and wherein the polymer is insoluble in the second solvent; adding the polymer solution to the dispersion medium to form a dispersed phase of polymer solution droplets within the dispersion medium; and introducing a shear stress to the dispersion medium and dispersed polymer solution droplets for a time and at a shear rate sufficient to elongate the polymer solution droplets to form microrods and solidify the microrods by attrition of the polymer solvent into the dispersion medium.
    Type: Application
    Filed: June 15, 2005
    Publication date: March 23, 2006
    Inventors: Orlin Velev, Rossitza Alargova