Patents by Inventor Roswitha BRAUNRATH

Roswitha BRAUNRATH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PRODUCING A CONTRAST AGENT
    Publication number: 20200390910
    Abstract: Disclosed is a process for producing a contrast agent-containing pharmaceutical preparation, which contains as the contrast agent a complex of a lanthanide, in particular gadolinium, and a macrocyclic chelate, in particular DOTA.
    Type: Application
    Filed: February 20, 2019
    Publication date: December 17, 2020
    Inventors: Stefan WELZIG, Beate KÄLZ, József GUNGL, Klaus GERDES, Roswitha BRAUNRATH, Christina ABRAHAMSBERG
  • Method for producing a liquid pharmaceutical preparation
    Patent number: 10064961
    Abstract: A method for producing a liquid pharmaceutical preparation which contains a complex consisting of DOTA and gadolinium and a base such as L-lysine or meglumine, includes the following steps: a) An aqueous solution containing free DOTA, free gadolinium and a base such as L-lysine or meglumine is produced. b) The yield of free DOTA and free gadolinium is determined in the solution obtained according to step a). c) Free gadolinium and/or free DOTA is added in order to adjust a stoichiometric excess of free DOTA in the solution. d) The complexation is executed at an increased temperature. e) Additional base such as L-lysine or meglumine is added in order to adjust the pH value. f) The final volume of the preparation is adjusted.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: September 4, 2018
    Assignee: SANOCHEMIA PHARMAZEUTIKA AG
    Inventors: Stefan Welzig, Raffael Schuecker, Beate Kaelz, Jozsef Gungl, Klaus Gerdes, Roswitha Braunrath
  • METHOD FOR PRODUCING A LIQUID PHARMACEUTICAL PREPARATION
    Publication number: 20170216462
    Abstract: A method for producing a liquid pharmaceutical preparation which contains a complex consisting of DOTA and gadolinium and a base such as L-lysine or meglumine, includes the following steps: a) An aqueous solution containing free DOTA, free gadolinium and a base such as L-lysine or meglumine is produced. b) The yield of free DOTA and free gadolinium is determined in the solution obtained according to step a). c) Free gadolinium and/or free DOTA is added in order to adjust a stoichiometric excess of free DOTA in the solution. d) The complexation is executed at an increased temperature. e) Additional base such as L-lysine or meglumine is added in order to adjust the pH value. f) The final volume of the preparation is adjusted.
    Type: Application
    Filed: June 15, 2015
    Publication date: August 3, 2017
    Inventors: Stefan WELZIG, Raffael SCHUECKER, Beate KAELZ, Jozsef GUNGL, Klaus GERDES, Roswitha BRAUNRATH