Abstract: A motion picture camera of the type which advances the film through a film gate in a stop-and-go motion and particularly designed for high speed operation, and comprising a film drive mechanism having a sprocket and two guide assemblies for forming and guiding a loop of film through the film gate, one of the guide assemblies being mounted on an eccentric for continuous rotation while moving the loop of film against a stationary registration pin in intermittent fashion, the registration pin being disposed for insertion through a perforation of the film when the eccentric crosses dead center, and the other guide assembly being a compact structure for cooperating with the first guide assembly to reduce any accumulation of the composite error in the perforations of the film; the camera is also constructed in two sections which are removably secured together by a release mechanism which is readily separable by one hand of the operator of the camera, one section of the camera containing a film supply reel and take-