Patents by Inventor Rowena L. Roberts

Rowena L. Roberts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing as partyl-phenylalanine dipeptides
    Patent number: 4873359
    Abstract: Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspartame or derivative by enzymatic coupling of phenylserine or derivative with aspartic acid or derivative. Hydrogenation of the coupled product to give as final product aspartame or analog with related processes and products.
    Type: Grant
    Filed: October 1, 1987
    Date of Patent: October 10, 1989
    Assignee: W. R. Grace & Co. - Conn.
    Inventors: Alan B. Chmurny, Akiva T. Gross, Robert J. Kupper, Rowena L. Roberts
  • Aspartyl-beta substituted phenylalanine dipeptides
    Patent number: 4810817
    Abstract: Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspartame or derivative by enzymatic coupling of phenylserine or derivative with aspartic acid or derivative. Hydrogenation of the coupled product to give as final product aspartame or analog with related processes and products.
    Type: Grant
    Filed: October 1, 1987
    Date of Patent: March 7, 1989
    Assignee: W. R. Grace & Co.
    Inventors: Alan B. Chmurny, Akiva T. Gross, Robert J. Kupper, Rowena L. Roberts
  • Dipeptides and process
    Patent number: 4710583
    Abstract: Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspertame or derivative by enzymatic coupling of phenylserine or derivative with aspertic acid or derivative. Hydrogenation of the coupled product to give as final product aspertame or analog with related processes and products.
    Type: Grant
    Filed: October 21, 1985
    Date of Patent: December 1, 1987
    Assignee: W. R. Grace & Co.
    Inventors: Alan B. Chmurny, Akiva T. Gross, Robert J. Kupper, Rowena L. Roberts