Patents by Inventor Roxanne D. Duan
Roxanne D. Duan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080146505Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: August 1, 2007Publication date: June 19, 2008Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Reinhard Ebner, Craig A. Rosen, Gregory A. Endress, Daniel R. Soppet, Jian Ni, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Henrik S. Olsen, Kimberly A. Florence
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Patent number: 6953667Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: GrantFiled: January 25, 2002Date of Patent: October 11, 2005Assignee: Human Genome Sciences, Inc.Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
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Patent number: 6936691Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: GrantFiled: April 11, 2001Date of Patent: August 30, 2005Assignee: Human Genome Sciences, Inc.Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi
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Publication number: 20040253684Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: July 7, 2004Publication date: December 16, 2004Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Reinhard Ebner, Craig A. Rosen, Gregory A. Endress, Daniel R. Soppet, Jian Ni, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Henrik S. Olsen, Kimberly A. Florence
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Publication number: 20040146893Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: October 15, 2003Publication date: July 29, 2004Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Craig A. Rosen, Paul E. Young, John M. Greene, Jian Ni, Ping Feng, Kimberly A. Florence, Jing-Shan Hu, Ann M. Ferrie, Guo-Liang Yu, Roxanne D. Duan, Fouad Janat
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Publication number: 20040048294Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: June 27, 2003Publication date: March 11, 2004Applicant: Human Genome Sciences,Inc.Inventors: Steven M. Ruben, Craig A. Rosen, Roxanne D. Duan, Yanggu Shi, David W. LaFleur, Paul E. Young, Jian Ni, George Komatsoulis, Gregory A. Endress, Daniel R. Soppet
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Publication number: 20040048271Abstract: The present invention relates to a novel human protein called Fibroblast Growth Factor 11, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.Type: ApplicationFiled: February 25, 2003Publication date: March 11, 2004Applicant: Human Genome Sciences, Inc.Inventors: Ralph Alderson, Robert J. Melder, Roxanne D. Duan, Craig A, Rosen, Jing-Shan Hu
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Publication number: 20040014954Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: ApplicationFiled: May 15, 2002Publication date: January 22, 2004Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Paul E. Young, Laurie A. Brewer, Reinhard Ebner, Henrik S. Olsen, Kimberly A. Florence, Craig A. Rosen, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Charles Florence, Daniel R. Soppet, Gregory A. Endress, Ping Feng, George A. Komatsoulis
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Publication number: 20040010132Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: October 30, 2001Publication date: January 15, 2004Inventors: Craig A. Rosen, Laurie A. Brewer, Roxanne D. Duan, Steven M. Ruben, Kimberly A. Florence, John M. Greene, Paul E. Young, Ann M. Ferrie, Guo-Liang Yu, Charles Florence, Reinhard Ebner, Henrik Olsen
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Publication number: 20030220489Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: October 9, 2002Publication date: November 27, 2003Applicant: Human Genome Sciences, Inc.Inventors: Craig A. Rosen, Steven M. Ruben, Reinhard Ebner, Roxanne D. Duan, Jian Ni, Daniel R. Soppet, Paul A. Moore, Yanggu Shi, David W. LaFleur, Henrik Olsen, Charles E. Birse, George A. Komatsoulis
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Publication number: 20030186904Abstract: This invention relates to newly identified polynucleotides, polypeptides encoded by such polynucleotides, the use of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides. More particularly, the polypeptide of the present invention is a Keratinocyte Growth Factor, sometimes hereinafter referred to as “KGF-2” also formerly known as Fibroblast Growth Factor 12 (FGF-12). This invention further relates to the therapeutic use of KGF-2 to promote or accelerate wound healing. This invention also relates to novel mutant forms of KGF-2 that show enhanced activity, increased stability, higher yield or better solubility.Type: ApplicationFiled: January 4, 2002Publication date: October 2, 2003Applicant: HUMAN GENOME SCIENCES, INC.Inventors: Steven M. Ruben, Pablo Jimenez, Roxanne D. Duan, Mark A. Rampy, Donna Mendrick, Jun Zhang, Jian Ni, Paul A. Moore, Timothy A. Coleman, Joachim R. Gruber, Patrick J. Dillon, Reiner L. Gentz
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Patent number: 6605441Abstract: The present invention relates to a novel human protein called Fibroblast Growth Factor 11, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.Type: GrantFiled: May 16, 2000Date of Patent: August 12, 2003Assignee: Human Genome Sciences, Inc.Inventors: Ralph Alderson, Robert J. Melder, Roxanne D. Duan, Craig A. Rosen, Jing-Shan Hu
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Patent number: 6566325Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: GrantFiled: July 16, 2001Date of Patent: May 20, 2003Assignee: Human Genome Sciences, Inc.Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
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Publication number: 20030087341Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: January 25, 2002Publication date: May 8, 2003Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
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Publication number: 20030078405Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: July 2, 2001Publication date: April 24, 2003Inventors: Steven M. Ruben, Reinhard Ebner, Craig A. Rosen, Gregory A. Endress, Daniel R. Soppet, Jian Ni, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Henrik S. Olsen, Kimberly A. Florence
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Publication number: 20030069405Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.Type: ApplicationFiled: May 15, 2002Publication date: April 10, 2003Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, Paul E. Young, Laurie A. Brewer, Reinhard Ebner, Henrik S. Olsen, Kimberly A. Florence, Craig A. Rosen, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Charles Florence, Daniel R. Soppet, Gregory A. Endress, Ping Feng, George A. Komatsoulis
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Patent number: 6534631Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: GrantFiled: January 13, 2000Date of Patent: March 18, 2003Assignee: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, George Komatsoulis, Roxanne D. Duan, Craig A. Rosen, Paul A. Moore, Yanggu Shi, David W. LaFleur, Reinhard Ebner, Henrik Olsen, Laurie A. Brewer, Kimberly A. Florence, Paul Young, Michael Mucenski, Gregory A. Endress, Daniel R. Soppet
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Publication number: 20030050455Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: February 6, 2001Publication date: March 13, 2003Inventors: Steven M. Ruben, Craig A. Rosen, Paul E. Young, John M. Greene, Jian Ni, Ping Feng, Kimberly A. Florence, Jing-Shan Hu, Ann M. Ferrie, Guo-Liang Yu, Roxanne D. Duan, Fouad Janat
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Publication number: 20030040088Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: October 29, 2001Publication date: February 27, 2003Applicant: Human Genome Sciences, Inc.Inventors: Steven M. Ruben, George Komatsoulis, Roxanne D. Duan, Craig A. Rosen, Paul A. Moore, Yanggu Shi, David W. LaFleur, Reinhard Ebner, Henrik S. Olsen, Laurie A. Brewer, Kimberly A. Florence, Paul E. Young, Michael Mucenski, Gregory A. Endress, Daniel R. Soppet
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Publication number: 20030027297Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.Type: ApplicationFiled: April 11, 2001Publication date: February 6, 2003Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi