Patents by Inventor Roy A. Bohenzky

Roy A. Bohenzky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the prevention of carryover contamination in nucleic acid amplification technologies
    Patent number: 8669061
    Abstract: An improved method of preventing carryover contamination of an amplification reaction involves treating uracil-containing DNA with uracil-N-DNA glycosylase and heating the DNA in the presence of polyamines, such as spermidine, spermine and the like. Alternatively, after treatment with uracil-N-DNA glycosylase, the reaction is further incubated with an enzyme having AP lyase activity.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: March 11, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Amar Gupta, Stephen Gordon Will, Roy Bohenzky, Janine Montiel
  • Method for the Prevention of Carryover Contamination in Nucleic Acid Amplification Technologies
    Publication number: 20100093041
    Abstract: An improved method of preventing carryover contamination of an amplification reaction involves treating uracil-containing DNA with uracil-N-DNA glycosylase and heating the DNA in the presence of polyamines, such as spermidine, spermine and the like. Alternatively, after treatment with uracil-N-DNA glycosylase, the reaction is further incubated with an enzyme having AP lyase activity.
    Type: Application
    Filed: June 16, 2009
    Publication date: April 15, 2010
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Amar Gupta, Stephen Gordon Will, Roy Bohenzky, Janine Montiel
  • Hepatitis virus sentinel virus I (SVI)
    Publication number: 20030198947
    Abstract: The invention relates to a new group of viruses, designated SVI. Isolated SVI viruses, polynucleotides and proteins from SVI viruses, and antibodies which bind SVI virus and SVI viral proteins are provided. The polynucleotides, proteins, and antibodies of the invention may be used to detect SVI virus or infection by SVI virus in a susceptible individual. Additionally, polynucleotides of the invention may be inserted into recombinant expression vectors recombinant production of viral proteins.
    Type: Application
    Filed: June 3, 2003
    Publication date: October 23, 2003
    Inventors: Jen-Kuei Liu, Roy A. Bohenzky, Yu-Huei Lin, Benjamin P. Chen
  • Sentinel virus II
    Publication number: 20030165540
    Abstract: The invention relates to a new virus, designated H101.c33 or Sentinel Virus II (SVII). Isolated SVII viruses, polynucleotides and proteins from SVII viruses, and antibodies which bind SVII virus and SVII viral proteins are provided. The polynucleotides, proteins, and antibodies of the invention may be used to detect SVII virus or infection by SVII virus in a susceptible individual. Additionally, polynucleotides of the invention may be inserted into recombinant expression vectors for recombinant production of viral proteins.
    Type: Application
    Filed: May 4, 2001
    Publication date: September 4, 2003
    Inventors: Jen-Kuei Liu, Samantha Lewis, Hans-Georg Batz, Latha Ramaswamy, Roy Bohenzky, Yu-Huei Lin, Janine Montiel, Benjamin P. Chen
  • Unique associated Kaposi's sarcoma virus sequences and uses thereof
    Patent number: 6348586
    Abstract: This invention provides an isolated nucleic acid molecule which encodes Kaposi's Sarcoma-Associated Herpesvirus (KSHV) polypeptides. This invention provides an isolated polypeptide molecule of KSHV. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: February 19, 2002
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Hepatitis virus sentinel virus I (SVI)
    Publication number: 20010034018
    Abstract: The invention relates to a new group of viruses, designated SVI. Isolated SVI viruses, polynucleotides and proteins from SVI viruses, and antibodies which bind SVI virus and SVI viral proteins are provided. The polynucleotides, proteins, and antibodies of the invention may be used to detect SVI virus or infection by SVI virus in a susceptible individual. Additionally, polynucleotides of the invention may be inserted into recombinant expression vectors recombinant production of viral proteins.
    Type: Application
    Filed: December 8, 2000
    Publication date: October 25, 2001
    Inventors: Jen-Kuei Liu, Roy A. Bohenzky, Yu-Huei Lin, Benjamin P. Chen
  • Unique associated Kaposi's Sarcoma virus sequences and uses thereof
    Patent number: 6183751
    Abstract: This invention provides an isolated nucleic acid molecule which encodes Kaposi's Sarcoma-Associated Herpesvirus (KSHV) polypeptides. This invention provides an isolated polypeptide molecule of KSHV. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
    Type: Grant
    Filed: November 29, 1996
    Date of Patent: February 6, 2001
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Immediate early protein from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof
    Patent number: 5948676
    Abstract: This invention provides an isolated nucleic acid molecule which encodes Kaposi's Sarcoma-Associated Herpesvirus (KSHV) immediate early protein (IEP). This invention provides an isolated polypeptide molecule which encodes KSHV immediate early protein. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
    Type: Grant
    Filed: October 10, 1996
    Date of Patent: September 7, 1999
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Kaposi's sarcoma-associated herpesvirus (KSHV) glycoprotein B (GB) and uses thereof
    Patent number: 5863787
    Abstract: This invention provides an isolated DNA molecule which encodes glycoprotein B (gB). Antisense and triplex oligonucleotide molecules are also provided.
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: January 26, 1999
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin 6 (IL-6) and uses thereof
    Patent number: 5861500
    Abstract: This invention provides an isolated DNA molecule which encodes interleukin 6 (IL-6) of Kaposi's sarcoma-associated herpesvirus. Antisense oligonucleotide molecules are also provided.
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: January 19, 1999
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Virion protein 26 from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof
    Patent number: 5859225
    Abstract: This invention provides an isolated nucleic acid molecule which encodes KSHV virion protein 26. This invention provides an isolated polypeptide molecule which encodes KSHV virion protein 26. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine and method of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
    Type: Grant
    Filed: September 5, 1996
    Date of Patent: January 12, 1999
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin 6 (IL-6) and uses thereof
    Patent number: 5854398
    Abstract: This invention provides an antibody specific to the peptide of KSHVIL-6.
    Type: Grant
    Filed: November 13, 1996
    Date of Patent: December 29, 1998
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Kaposi's sarcoma-associated herpesvirus (KSHV) viral macrophage inflammatory protein-1.alpha. II (vMIP-1.alpha. II) and uses thereof
    Patent number: 5854418
    Abstract: This invention provides an isolated DNA molecule which encodes viral macrophage inflammatory protein-1.alpha. II (vMIP-1.alpha. II). Antisense and oligonucleotide molecules are also provided.
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: December 29, 1998
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Glycoprotein L and clycoprotein M from kaposi's sarcoma associated herpesvirus, DNA encoding same and uses thereof
    Patent number: 5853734
    Abstract: This invention provides an isolated nucleic acid molecule which encodes KSHV glycoprotein L (gL). This invention provides an isolated nucleic acid molecule which encodes KSHV glycoprotein M (gM). This invention provides isolated gL and gM polypeptides. This invention provides antibodies specific to the polypeptides. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
    Type: Grant
    Filed: November 13, 1996
    Date of Patent: December 29, 1998
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Polypeptides from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof
    Patent number: 5849564
    Abstract: This invention provides an isolated nucleic acid molecule which encodes Kaposi's Sarcoma-Associated Herpesvirus (KSHV) polypeptides. This invention provides an isolated polypeptide molecule of KSHV. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
    Type: Grant
    Filed: November 29, 1996
    Date of Patent: December 15, 1998
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
  • Kaposi's sarcoma-associated herpes virus (KSHV) interferon consensus sequence binding protein (ICSBP) and uses thereof
    Patent number: 5831064
    Abstract: This invention provide an isolated DNA molecule which encodes interferon consensus sequence binding protein (ICSBP).
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: November 3, 1998
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Yuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore