Abstract: A modeling arrangement for an anatomical organ is provided with a plurality of substructure models corresponding to predetermined substructures of the anatomical organ. Such substructures may include representations of organs, volumes, vessels, and fluids which assume predetermined shapes with the anatomical organ being modeled. The arrangement is provided with one or more members which define the surface of the anatomical organ being modeled; the members being couplable to a base member. Preferably, all of the members, including the base member, which support the substructures are formed of a transparent material, preferably one of the type marketed under the Plexiglas trademark. The modeling arrangement may be used in conjunction with written instructions to form a self-learning system which is particularly useful for students of anatomy. In one highly advantageous embodiment of the invention, a biological brain, particularly the fore-brain portion, is represented by the inventive modeling scheme.