Patents by Inventor Roy A. Swaringen, Jr.

Roy A. Swaringen, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110224448
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Application
    Filed: May 25, 2011
    Publication date: September 15, 2011
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, JR., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Patent number: 7994351
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: August 9, 2011
    Assignee: Kythera Biopharmaceuticals, Inc.
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, Jr., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Publication number: 20110152552
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Application
    Filed: January 20, 2011
    Publication date: June 23, 2011
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, JR., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Patent number: 7902387
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: March 8, 2011
    Assignee: Kythera Biopharmaceuticals, Inc.
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, Jr., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Publication number: 20100145083
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Application
    Filed: November 6, 2009
    Publication date: June 10, 2010
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, JR., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Publication number: 20090270642
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Application
    Filed: May 16, 2008
    Publication date: October 29, 2009
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, JR., John Gregory Reid, Robert M. Moriarty
  • Patent number: 4761418
    Abstract: Neuromuscular blocking agents of formula (1) which are useful as skeletal muscle relaxants during surgery are disclosed. ##STR1## and X is an anion, preferably pharmaceutically acceptable.
    Type: Grant
    Filed: July 17, 1985
    Date of Patent: August 2, 1988
    Assignees: Burroughs Wellcome Co., General Hospital Corporation
    Inventors: Roy A. Swaringen, Jr., Hassan A. El-Sayad, David A. Yeowell, John J. Savarese
  • Patent number: 4701460
    Abstract: Long duration muscle relaxant compound of formula (I) ##STR1## and its use in producing muscle relaxation in mammals including man.
    Type: Grant
    Filed: January 25, 1985
    Date of Patent: October 20, 1987
    Assignee: Burroughs Wellcome Co.
    Inventors: Hassan A. El-Sayad, Roy A. Swaringen, Jr., David A. Yeowell
  • Patent number: 4568744
    Abstract: 2,4-Diamino-5-(4-amino- and 4-loweralkylamino-3,5-disubstitutedbenzyl)pyrimidines are prepared by a novel method using 2,6-disubstituted anilines and pyrimidines. Several novel intermediates are involved.
    Type: Grant
    Filed: May 14, 1984
    Date of Patent: February 4, 1986
    Assignee: Burroughs Wellcome Co.
    Inventors: Roy A. Swaringen, Jr., John F. Eaddy, III, Thomas R. Henderson
  • Patent number: 4491665
    Abstract: This invention provides the neuromuscular blocking agents of formula (I): ##STR1## where B and C are each a group of formula (II) and are meta or para to one another: ##STR2## wherein D is CH.sub.2 CH.sub.2 or CH.dbd.CH (preferably trans); Y is alkyl of 1-4 carbon atoms (methyl, ethyl, propyl or butyl); E and F and H or OCH.sub.3 ; X.sup.- is an anion, preferably pharmaceutically acceptable; and the substituted benzyl and substituted propyl groups are in a trans relationship relative to each other in the nitrogen-containing ring.Methods for preparing the compounds, pharmaceutical formulations containing the compounds, and their use are also described.
    Type: Grant
    Filed: April 13, 1981
    Date of Patent: January 1, 1985
    Assignee: Burroughs Wellcome Co.
    Inventors: Hassan A. El-Sayad, Roy A. Swaringen, Jr., David A. Yeowell
  • Patent number: 4216319
    Abstract: Benzyl cyanoacetals of formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are the same or different and each is a halogen or a hydrogen atom, an alkoxy group, an alkyl group, or a dialkylamino group; R.sup.4 is an alkoxycarbonyl group, or an aldehyde group; and R.sup.5 is an alkyl group; the alkyl or alkoxy groups each having from 1 to 4 carbon atoms, and their use as intermediates in the preparation of antibacterial 2,4-diamino-5-benzylpyrimidines. They are prepared from a reaction between an orthoester and an .alpha.-substituted-.beta.-benzylpropionitrile and then the resulting cyanoacetal is converted to the benzylpyrimidine by reaction with guanidine.
    Type: Grant
    Filed: November 24, 1978
    Date of Patent: August 5, 1980
    Assignee: Burroughs Wellcome Co.
    Inventors: David A. Yeowell, Roy A. Swaringen, Jr.
  • Patent number: 4144263
    Abstract: Benzyl cyanoacetals of formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are the same or different and each is a halogen or a hydrogen atom, an alkoxy group, an alkyl group, or a dialkylamino group; R.sup.4 is an alkoxycarbonyl group, or an aldehyde group;And R.sup.5 is an alkyl group; the alkyl or alkoxy groups each having from 1 to 4 carbon atoms, and their use as intermediates in the preparation of antibacterial 2,4-diamino-5-benzylpyrimidines. They are prepared from a reaction between an orthoester and an .alpha.-substituted-.beta.-benzylpropionitrile and then the resulting cyanoacetal is converted to the benzyl-pyrimidine by reaction with guanidine.
    Type: Grant
    Filed: June 8, 1977
    Date of Patent: March 13, 1979
    Assignee: Burroughs Wellcome Co.
    Inventors: David A. Yeowell, Roy A. Swaringen, Jr.