Patents by Inventor Roy Calne

Roy Calne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
    Patent number: 5461058
    Abstract: This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
    Type: Grant
    Filed: January 24, 1995
    Date of Patent: October 24, 1995
    Inventor: Roy Calne
  • Methods of inhibiting transplant rejecton in mammals using rapamycin and derivatives and prodrugs thereof
    Patent number: 5403833
    Abstract: This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
    Type: Grant
    Filed: February 7, 1994
    Date of Patent: April 4, 1995
    Inventor: Sir Roy Calne
  • Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
    Patent number: 5308847
    Abstract: This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
    Type: Grant
    Filed: January 26, 1993
    Date of Patent: May 3, 1994
    Inventor: Sir Roy Calne
  • Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
    Patent number: 5212155
    Abstract: This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
    Type: Grant
    Filed: July 31, 1991
    Date of Patent: May 18, 1993
    Inventor: Roy Calne
  • Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
    Patent number: 5100899
    Abstract: This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
    Type: Grant
    Filed: June 6, 1989
    Date of Patent: March 31, 1992
    Inventor: Roy Calne