Abstract: A method and apparatus for non-invasively diagnosing a condition of subcutaneous biological tissue using biomolecular Raman spectroscopy. The apparatus is immobilized against the skin of a user so that a light source can emit photons of light through a bottom port that probes physiological biomarkers in molecules of interest in subcutaneous tissue. Photons of Rayleigh scattered light commingled with Raman scattered light are returned into the internal cavity through the port. After having been filtered of Rayleigh scattered light and limited to a specific wavelength, the photons are detected in an array of photodetectors where photons of Raman scattered light are singly counted over a predetermined sampling time. The apparatus and method can be configured in wearable form, for example a wristband, to monitor a variety of conditions, including reading blood sugar.

Abstract: Cerenkov Emission (CE) during external beam radiation therapy (EBRT) from a linear accelerator (Linac) has been demonstrated as a useful tool for radiotherapy quality assurance and potentially other applications for online tracking of tumors during treatment. However, an overlooked area is the molecular probing of the cancer status during delivery mainly due to the limited detection sensitivity of CE and lack of flexible tools to fit into an already complex treatment delivery environment. Silicon photomultiplier (SiPM) can be used for low light detection due to their extreme sensitivity that mirrors photomultiplier tubes and yet has a form factor that is similar to silicon photodiodes, allowing for improved flexibility in device design. This work assesses the feasibility of using SiPMs to detect CE, interrogate the tumor molecular status during EBRT, and contrast its performance with silicon photodiodes (PDs) available commercially.

Abstract: Cerenkov Emission (CE) during external beam radiation therapy (EBRT) from a linear accelerator (Linac) has been demonstrated as a useful tool for radiotherapy quality assurance and potentially other applications for online tracking of tumors during treatment. However, an overlooked area is the molecular probing of the cancer status during delivery mainly due to the limited detection sensitivity of CE and lack of flexible tools to fit into an already complex treatment delivery environment. Silicon photomultiplier (SiPM) can be used for low light detection due to their extreme sensitivity that mirrors photomultiplier tubes and yet has a form factor that is similar to silicon photodiodes, allowing for improved flexibility in device design. This work assesses the feasibility of using SiPMs to detect CE, interrogate the tumor molecular status during EBRT, and contrast its performance with silicon photodiodes (PDs) available commercially.

Abstract: An optoelectronic neutron detector and method for detecting nuclear material having a neutron capture and scatter medium receiving neutrons and producing secondary charged particles, a photodetector detecting emitted light from the secondary charged particles and outputting a detector signal, and a controller receiving the detector signal and providing an alert or quantitative indication of detected nuclear material in response to the detector signal.

Abstract: An optoelectronic neutron detector and method for detecting nuclear material having a neutron capture and scatter medium receiving neutrons and producing secondary charged particles, a photodetector detecting emitted light from the secondary charged particles and outputting a detector signal, and a controller receiving the detector signal and providing an alert or quantitative indication of detected nuclear material in response to the detector signal.

Abstract: A multilayer stack including a substrate, an active layer, and a tetradymite buffer layer positioned between the substrate and the active layer is disclosed. A method for fabricating a multilayer stack including a substrate, a tetradymite buffer layer and an active layer is also disclosed. Use of such stacks may be in photovoltaics, solar cells, light emitting diodes, and night vision arrays, among other applications.

Abstract: A multilayer stack including a substrate, an active layer, and a tetradymite buffer layer positioned between the substrate and the active layer is disclosed. A method for fabricating a multilayer stack including a substrate, a tetradymite buffer layer and an active layer is also disclosed. Use of such stacks may be in photovoltaics, solar cells, light emitting diodes, and night vision arrays, among other applications.

Abstract: The invention is an optical method and apparatus for measuring the temperature of semiconductor substrates in real-time, during thin film growth and wafer processing. Utilizing the nearly linear dependence of the interband optical absorption edge on temperature, the present method and apparatus result in highly accurate measurement of the absorption edge in diffuse reflectance and transmission geometry, in real time, with sufficient accuracy and sensitivity to enable closed loop temperature control of wafers during film growth and processing. The apparatus operates across a wide range of temperatures covering all of the required range for common semiconductor substrates.

Abstract: The present invention relates to biological sensors. In particular, the present invention relates to the use of remotely driven nonlinear rotation of particles (e.g., magnetic particles) for detection of cells such as microorganisms (e.g., bacteria and viruses). The present invention further relates to the use of remotely driven nonlinear rotation of particles for measurement of physical properties of a solution (e.g., viscosity).

Abstract: Described herein are various methods, devices and systems for performing asynchronous magnetic bead rotation (AMBR) to detect and monitor cellular growth and/or behavior. Cluster rotation of magnetic particles for AMBR is descried. In particular, described herein are systems for the parallel analysis of multiple wells of a sample plate. Also described herein are methods for controlling the illumination and imaging of rotating magnetic particles.

Abstract: In one embodiment of the invention, an apparatus for a juicer includes: a cutting chamber; a squeezing chamber adjacent to the cutting chamber; wherein the cutting chamber includes a cutter; and wherein the squeezing chamber includes a press. In another embodiment of the invention, a method of assembling a juicer includes: providing a cutting chamber; placing at least one cutter in the cutting chamber; providing a squeezing chamber in a position adjacent to the cutting chamber; and providing a press in the squeezing chamber.

Abstract: In one embodiment of the invention, an apparatus for a juicer includes: a cutting chamber; a squeezing chamber adjacent to the cutting chamber; wherein the cutting chamber includes a cutter; and wherein the squeezing chamber includes a press. In another embodiment of the invention, a method of assembling a juicer includes: providing a cutting chamber; placing at least one cutter in the cutting chamber; providing a squeezing chamber in a position adjacent to the cutting chamber; and providing a press in the squeezing chamber.

Abstract: A method of measuring at least one property including a magnetic property of target material is provided. A pump pulse train having one or more pump pulses is generated. The target material is irradiated with at least a portion of the one or more pump pulses so as to cause transient perturbation in the target material. At least one probe pulse train is generated having one or more probe pulses. The target material is irradiated with at least a portion of the one or more probe pulses to obtain one or more reflected probe pulses which are modulated based on the transient perturbation. A time interval between a time at which the target material is irradiated by each of the pump pulses and a time at which the target material is irradiated by each of its corresponding probe pulses is controlled. Each modulated probe pulse is detected.

Abstract: Described herein are various methods, devices and systems for performing asynchronous magnetic bead rotation (AMBR) to detect and monitor cellular growth and/or behavior. Cluster rotation of magnetic particles for AMBR is descried. In particular, described herein are systems for the parallel analysis of multiple wells of a sample plate. Also described herein are methods for controlling the illumination and imaging of rotating magnetic particles.

Abstract: A detector having a thin film of boron nitride (BN) such as cubic BN, and method, system and array utilizing same are provided. Solid-state p-i-n, deep depletion p-n and Schottky diode detector devices based on a thin film of semiconducting cubic BN are provided. Miniaturized solid-state detectors based on cubic boron nitride have a broad range of applications, both civilian and military.

Abstract: The invention is an optical method and apparatus for measuring the temperature of semiconductor substrates in real-time, during thin film growth and wafer processing. Utilizing the nearly linear dependence of the interband optical absorption edge on temperature, the present method and apparatus result in highly accurate measurement of the absorption edge in diffuse reflectance and transmission geometry, in real time, with sufficient accuracy and sensitivity to enable closed loop temperature control of wafers during film growth and processing. The apparatus operates across a wide range of temperatures covering all of the required range for common semiconductor substrates.

Abstract: The invention is an optical method and apparatus for measuring the temperature of semiconductor substrates in real-time, during thin film growth and wafer processing. Utilizing the nearly linear dependence of the interband optical absorption edge on temperature, the present method and apparatus result in highly accurate measurement of the absorption edge in diffuse reflectance and transmission geometry, in real time, with sufficient accuracy and sensitivity to enable closed loop temperature control of wafers during film growth and processing. The apparatus operates across a wide range of temperatures covering all of the required range for common semiconductor substrates.

Abstract: A method of measuring at least one property including a magnetic property of target material is provided. The method includes the step of generating a pump pulse train having one or more pump pulses at a repetition rate along a first propagation path, each pump pulse having a pulse energy density, a laser wavelength within a range of laser wavelengths, and a pulse duration The method further includes the step of irradiating the target material with at least a portion of the one or more pump pulses focused into at least one spot having a spot shape and size so as to cause transient perturbation in the target material. The method still further includes the step of generating at least one probe pulse train having one or more probe pulses at a repetition rate along a second propagation path, each probe pulse having a pulse energy density, a laser wavelength within a range of laser wavelengths, and a pulse duration.

Abstract: The invention is an optical method and apparatus for measuring the temperature of semiconductor substrates in real-time, during thin film growth and wafer processing. Utilizing the nearly linear dependence of the interband optical absorption edge on temperature, the present method and apparatus result in highly accurate measurement of the absorption edge in diffuse reflectance and transmission geometry, in real time, with sufficient accuracy and sensitivity to enable closed loop temperature control of wafers during film growth and processing. The apparatus operates across a wide range of temperatures covering all of the required range for common semiconductor substrates.

Abstract: A detector having a thin film of boron nitride (BN) such as cubic BN, and method, system and array utilizing same are provided. Solid-state p-i-n, deep depletion p-n and Schottky diode detector devices based on a thin film of semiconducting cubic BN are provided. Miniaturized solid-state detectors based on cubic boron nitride have a broad range of applications, both civilian and military.