Patents by Inventor Roy Eugene Snoke

Roy Eugene Snoke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analytical, element, composition and method using modified apo-horseradish peroxidase
    Patent number: 5776714
    Abstract: Modified apo-peroxidases have been found useful in analytical methods to remove the bias caused by the presence of hemoglobin in the test specimens. While apo-peroxidases are known to remove serum interferents, they fail to overcome the hemoglobin bias, particularly when dry coated analytical elements are used in the assays. Blocking the nitrogen atoms of the imidzolyl groups of the histidine amino acids of the apo-peroxidase prevents catalytic activity of the protein in the presence of hemoglobin.
    Type: Grant
    Filed: October 10, 1995
    Date of Patent: July 7, 1998
    Assignee: Johnson & Johnson Clinical Diagnostics Inc.
    Inventor: Roy Eugene Snoke
  • Reduction in first slide bias and improved enzyme stability by the incorporation of diaryl tellurides in thin-film immunoassay elements
    Patent number: 5686254
    Abstract: A dry immunoassay analytical element for assaying a ligand, comprising a support bearing:1. an enzyme labeled ligand or an enzyme labeled receptor zone;2. a spreading zone; and3. a receptor zone containing a fixed concentration of an immobilized receptor for the ligand and the labeled ligand when present and the receptor is covalently bonded to polymeric beads having a diameter in the range of 0.1 to 5 .mu.m; characterized in that the element contains a diaryl telluride (DAT) compound and the zones can be in the same or separate layers.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 11, 1997
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Margaret Elizabeth Logan, Carol Anne DeCann, Marsha Denise Bale Oenick, Gary Louis Snodgrass, Roy Eugene Snoke
  • Composition for chromatography
    Patent number: 4111838
    Abstract: A chromatographic material comprising an inorganic support-polysaccharide particle matrix is described. The matrix comprises an inorganic support having a high surface density of hydroxyl groups and, covalently attached thereto, insoluble particles of a polysaccharide. The free hydroxyl groups of the matrix can be activated, say, by treatment with cyanogen bromide or sodium metaperiodate, to form active sites where ligands can be attached for affinity chromatography.
    Type: Grant
    Filed: September 9, 1977
    Date of Patent: September 5, 1978
    Assignee: Eastman Kodak Company
    Inventors: James Robert Schaeffer, Roy Eugene Snoke, Harry Wayne Harris
  • Purification of uricase
    Patent number: 4064010
    Abstract: Catalase is effectively removed from a uricase preparation by amphiphilic chromotography using as the column material cyanogen bromide-activated polysaccharide having a hydrophobic ligand attached thereto. Particularly useful hydrophobic ligands are the alkanediamines.
    Type: Grant
    Filed: July 21, 1976
    Date of Patent: December 20, 1977
    Assignee: Eastman Kodak Company
    Inventors: Harry Wayne Harris, James Robert Schaeffer, Roy Eugene Snoke
  • Production of uricase from micrococcus luteus
    Patent number: 4062731
    Abstract: A stable uricase preparation of high activity is produced by growing Micrococcus luteus NRRL B-8166 in a nutrient medium. Uricase preparations having activities of up to about 1000 U/liter are produced.
    Type: Grant
    Filed: July 21, 1976
    Date of Patent: December 13, 1977
    Assignee: Eastman Kodak Company
    Inventors: Roy Eugene Snoke, Hugh Arthur Risley, Charles Thomas Goodhue
  • Purification of microbial enzyme extracts using synthetic polyelectrolytes
    Patent number: 4055469
    Abstract: Nucleic acids and unwanted proteins are removed from microbial enzyme extracts by precipitation with water-soluble, cationic polymers comprised of monomers having the structure ##STR1## wherein R.sub.1 is a hydrogen atom, a lower alkyl group, or the equivalent and R.sub.2 is a nitrogen containing group capable of carrying a positive electrical charge when the polymer is dissolved in an aqueous solution.
    Type: Grant
    Filed: December 10, 1976
    Date of Patent: October 25, 1977
    Assignee: Eastman Kodak Company
    Inventors: Roy Eugene Snoke, Gerald Wayne Klein