Patents by Inventor Roy H. Doi

Roy H. Doi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of detection using a cellulose binding domain fusion product
    Patent number: 5856201
    Abstract: A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
    Type: Grant
    Filed: October 27, 1994
    Date of Patent: January 5, 1999
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, The University of California
    Inventors: Oded Shoseyov, Itai Shpiegl, Marc A. Goldstein, Roy H. Doi
  • Cellulose binding domain fusion proteins
    Patent number: 5719044
    Abstract: A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: February 17, 1998
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, Regents of the University of California
    Inventors: Oded Shoseyov, Itai Shpiegl, Marc A. Goldstein, Roy H. Doi
  • Methods of use of cellulose binding domain proteins
    Patent number: 5670623
    Abstract: A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: September 23, 1997
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, The University of California
    Inventors: Oded Shoseyov, Itai Shpiegl, Marc A. Goldstein, Roy H. Doi
  • Extracellular serine protease and a Bacillus subtilis alkaline neutral an serine protease mutant strain
    Patent number: 5585253
    Abstract: A cloned gene (epr) encoding a novel extracellular protease, Epr, from Bacillus subtilis is described. Also described is a triple extracellular neutral, alkaline and serine protease deficient Bacillus subtilis mutant strain having deletions in the (npr), (apr) and (epr) genes encoding these proteases. The triple mutant strain was constructed by the gene conversion technique and produces about 1% of the extracellular proteolytic activity of the wild type. It is a particularly useful host for the production of heterologous proteins that are secreted into the growth medium.
    Type: Grant
    Filed: November 27, 1989
    Date of Patent: December 17, 1996
    Assignee: The Regents of the University of California
    Inventors: Roy H. Doi, Lin-Fa Wang, Reinhold Br uckner
  • Nucleic acids encoding a cellulose binding domain
    Patent number: 5496934
    Abstract: A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
    Type: Grant
    Filed: April 14, 1993
    Date of Patent: March 5, 1996
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, The Regents of the University of California
    Inventors: Oded Shoseyov, Itai Shpiegl, Marc A. Goldstein, Roy H. Doi