Patents by Inventor Roy H. Larsen

Roy H. Larsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF HIGHLY PURIFIED 212PB
    Publication number: 20250210211
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb in high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Application
    Filed: November 7, 2024
    Publication date: June 26, 2025
    Applicant: Sciencons AS
    Inventor: Roy H. Larsen
  • PRODUCTION OF HIGHLY PURIFIED 212PB
    Publication number: 20250210213
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb in high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Application
    Filed: March 11, 2025
    Publication date: June 26, 2025
    Applicant: Sciencons AS
    Inventor: Roy H. Larsen
  • Production Of Highly Purified 212PB
    Publication number: 20250210212
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb in high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Application
    Filed: November 7, 2024
    Publication date: June 26, 2025
    Applicant: Sciencons AS
    Inventor: Roy H. Larsen
  • Production of Highly Purified 212PB
    Publication number: 20250201434
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb in high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Application
    Filed: November 7, 2024
    Publication date: June 19, 2025
    Applicant: Sciencons AS
    Inventor: Roy H. LARSEN
  • COMPLEXES FOR CANCER TREATMENT AND IMAGING
    Publication number: 20250099631
    Abstract: The present invention relates to complexes comprising a PSMA targeting compound linked to a radionuclide such as 47Sc, 111In, 161Tb. These compounds, and pharmaceutical compositions comprising them, can be used for medical applications, including in the treatment of cancer as well as in monitoring and diagnostics.
    Type: Application
    Filed: January 20, 2023
    Publication date: March 27, 2025
    Inventor: Roy H. LARSEN
  • Production of highly purified 212PB
    Patent number: 12249437
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb in high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Grant
    Filed: May 31, 2024
    Date of Patent: March 11, 2025
    Assignee: Sciencons AS
    Inventor: Roy H. Larsen
  • PRODUCTION OF HIGHLY PURIFIED 212PB
    Publication number: 20250069768
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb in high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Application
    Filed: November 8, 2024
    Publication date: February 27, 2025
    Applicant: Sciencons AS
    Inventor: Roy H. Larsen
  • PRODUCTION OF HIGHLY PURIFIED 212PB
    Publication number: 20240395432
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb in high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Application
    Filed: May 31, 2024
    Publication date: November 28, 2024
    Applicant: Sciencons AS
    Inventor: Roy H. Larsen
  • Production of highly purified Pb
    Patent number: 12125603
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: October 22, 2024
    Assignee: Sciencons AS
    Inventor: Roy H. Larsen
  • PRODUCTION OF HIGHLY PURIFIED 212PB
    Publication number: 20240331888
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb in high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Application
    Filed: May 31, 2024
    Publication date: October 3, 2024
    Applicant: Sciencons AS
    Inventor: Roy H. Larsen
  • SIZE CONTROLLED RADIOLABELLED PARTICLES
    Publication number: 20230372554
    Abstract: The present disclosure relates to a particle comprising a degradable compound, a radionuclide, and a phosphorus containing additive. Phosphorus containing additives, such as phosphonates, have the unique ability to control the size of particles for medical applications. The applications allow for use of the particles as medicaments and for imaging, especially within the field of cancer.
    Type: Application
    Filed: September 15, 2021
    Publication date: November 23, 2023
    Inventors: Roy H. Larsen, Tina B. Bønsdorff
  • PRODUCTION OF HIGHLY PURIFIED 212PB
    Publication number: 20230014219
    Abstract: The present invention relates to assemblies and method for obtaining a container comprising 212Pb on the walls obtained from a 212Pb precursor isotope source. The invention provides an improved system and method for producing 212Pb high purity without the need for processing, with high yields, and which safely and efficiently can be transported to the locations where it is to be used.
    Type: Application
    Filed: December 4, 2020
    Publication date: January 19, 2023
    Inventor: Roy H. Larsen
  • Method for upregulating antigen expression
    Patent number: 10646599
    Abstract: The present invention relates to radioimmunoconjugates that are capable of upregulating expression of one or more antigens. The upregulated antigens can be the antigens that are targeted by the radioimmunoconjugates or different antigens expressed on the same cells. The present invention also relates to methods of treating cancer and diseases and disorders of the immune system by utilizing this enhanced expression of antigens.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: May 12, 2020
    Assignee: NORDIC NANOVECTOR ASA
    Inventors: Roy H. Larsen, Ada Repetto-Llamazares
  • METHOD FOR UPREGULATING ANTIGEN EXPRESSION
    Publication number: 20190008989
    Abstract: The present invention relates to radioimmunoconjugates that are capable of upregulating expression of one or more antigens. The upregulated antigens can be the antigens that are targeted by the radioimmunoconjugates or different antigens expressed on the same cells. The present invention also relates to methods of treating cancer and diseases and disorders of the immune system by utilizing this enhanced expression of antigens.
    Type: Application
    Filed: June 13, 2018
    Publication date: January 10, 2019
    Inventors: Roy H. Larsen, Ada Repetto-Llamazares
  • CHIMERIC THERAPEUTIC ANTI - CD37 ANTIBODIE HH1
    Publication number: 20180194852
    Abstract: The present invention relates to chimeric or humanized antibodies derived from the mouse monoclonal antibody HH1. The applications of the present invention include therapeutic applications in which pharmaceutical compositions comprising the antibodies of the present invention or radioimmunoconjugates hereof are used for treating B-cell malignancies.
    Type: Application
    Filed: December 19, 2017
    Publication date: July 12, 2018
    Inventors: Roy H. Larsen, Jostein Dahle
  • Radioimunoconjugates and uses thereof
    Patent number: 9358309
    Abstract: The present invention relates to a radioimmunoconjugate that binds human CD37. Pharmaceutical compositions and uses thereof for the treatment of cancer and in particular B cell malignancies are aspects of the present invention.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: June 7, 2016
    Assignee: Nordic Nanovector AS
    Inventors: Roy H. Larsen, Jostein Dahle, Øyvind S. Bruland
  • METHOD FOR UPREGULATING ANTIGEN EXPRESSION
    Publication number: 20160101199
    Abstract: The present invention relates to radioimmunoconjugates that are capable of upregulating expression of one or more antigens. The upregulated antigens can be the antigens that are targeted by the radioimmunoconjugates or different antigens expressed on the same cells. The present invention also relates to methods of treating cancer and diseases and disorders of the immune system by utilizing this enhanced expression of antigens.
    Type: Application
    Filed: June 6, 2014
    Publication date: April 14, 2016
    Inventors: Roy H. Larsen, Ada Repetto-Llamazares
  • RECEPTOR BINDING CONJUGATES
    Publication number: 20150258223
    Abstract: The present invention relates to a receptor binding conjugate which consists of an antibody, a radionuclide and folate or a folate derivative, wherein or not the conjugate possesses dual binding ability. The present invention also relates to a method and a kit to prepare, as well as a method to use, such conjugates. Furthermore, the use of a conjugate according to the present invention to prepare a pharmaceutical solution is disclosed.
    Type: Application
    Filed: December 16, 2014
    Publication date: September 17, 2015
    Inventors: Roy H. LARSEN, Gjermund HENRIKSON
  • CHIMERIC THERAPEUTIC ANTI - CD37 ANTIBODIE HH1
    Publication number: 20140348745
    Abstract: The present invention relates to chimieric or humanized antibodies derived from the mouse monoclonal antibody HH1. The applications of the present invention include therapeutic applications in which pharmaceutical compositions comprising the antibodies of the present invention or radioimmunoconjugates hereof are used for treating B-cell malignancies.
    Type: Application
    Filed: December 12, 2012
    Publication date: November 27, 2014
    Inventors: Roy H. Larsen, Jostein Dahle
  • METHOD OF RADIOTHERAPY
    Publication number: 20140235924
    Abstract: The invention provides a method for the treatment of soft tissue disease in a mammalian subject (preferably a human or canine subject), said method comprising administering to said subject a therapeutically effective quantity of a soft tissue targeting complex of thorium-227 and a complexing agent, wherein said quantity is such that an acceptably non-myelotoxic quantity of radium-223 is generated in vivo by nuclear decay of the administered thorium-227.
    Type: Application
    Filed: February 19, 2014
    Publication date: August 21, 2014
    Applicant: Algeta ASA
    Inventors: Roy H. LARSEN, Oyvind S. BRULAND