Patents by Inventor Roy J. Vaz

Roy J. Vaz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMINO-BENZOIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DIHYDROGENASE-RELATED DISORDERS
    Publication number: 20120208855
    Abstract: Provided herein is method of modulating, and in particular decreasing dihydroorotate dehydrogenase (DHODH) activity, as well as a method of treating a DHODH related disease or disorder.
    Type: Application
    Filed: October 15, 2010
    Publication date: August 16, 2012
    Applicant: SANOFI
    Inventors: Larry Raymond Mclean, Arun Subramaniam, Roy J. Vaz, Yi Li
  • Polynucleotides encoding novel cysteine proteases of the calpain superfamily, CAN-12v1 and CAN-12v2.
    Patent number: 7186564
    Abstract: The present invention provides novel polynucleotides encoding CAN-12 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants of CAN-12 polypeptides, CAN-12v1 and CAN-12v2. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel CAN-12, CAN-12v1, and CAN-12v2 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly neuro- and musculo-degenerative conditions. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: April 3, 2002
    Date of Patent: March 6, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jian Chen, Thomas C. Nelson, Roy J. Vaz, Franck Duclos
  • 2-substituted cyclic amines as calcium sensing receptor modulators
    Patent number: 7105537
    Abstract: The present invention relates to modulators of the calcium sensing receptor having the formula I wherein Ar1, X, n, R1, R2, R3 and Q are as defined herein.
    Type: Grant
    Filed: January 27, 2004
    Date of Patent: September 12, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ashvinikumar V. Gavai, Roy J. Vaz, John K. Dickson, Jr., Jacques Y. Roberge, Wu Yang, Timur Gungor, James R. Corte, David P. Rotella, Yufeng Wang
  • Novel 2-substituted cyclic amines as calcium sensing receptor modulators
    Publication number: 20040229860
    Abstract: The present invention relates to modulators of the calcium sensing receptor having the formula I 1
    Type: Application
    Filed: January 27, 2004
    Publication date: November 18, 2004
    Inventors: Ashvinikumar V. Gavai, Roy J. Vaz, John K. Dickson, Jacques Y. Roberge, Wu Yang, Timur Gungor, James R. Corte, David P. Rotella, Yufeng Wang
  • Polynucleotide encoding a novel cysteine protease of the calpain superfamily, CAN-12, and variants thereof
    Publication number: 20030114373
    Abstract: The present invention provides novel polynucleotides encoding CAN-12 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants of CAN-12 polypeptides, CAN-12v1 and CAN-12v2. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel CAN-12, CAN-12v1, and CAN-12v2 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly neuro- and musculo-degenerative conditions. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Application
    Filed: April 3, 2002
    Publication date: June 19, 2003
    Inventors: Jian Chen, John N. Feder, Thomas C. Nelson, Steven Seiler, Roy J. Vaz, Franck Duclos