Abstract: The disclosure relates to embodiments of an apparatus for producing polymer composite panels. The polymer composite panels include one or more layers of a polymeric matrix having discontinuous fibers embedded therein. The apparatus has a frame, a deposition bed, and a deposition head configured to move relative to the frame and over the deposition bed. The deposition head includes at least one extruder and a nozzle array. The extruder is configured to force the polymeric matrix and discontinuous fibers through the nozzle array and onto the deposition bed. The deposition head is configured to deposit an entire layer of a polymer composite panel on the deposition bed in a single pass so that the discontinuous fibers are oriented in the direction of the single pass. The disclosure also relates to embodiments of a method of forming a polymer composite panel and to embodiments of a polymer composite panel.

Abstract: A stent for a respiratory organ, the stent having an inside surface and an outside surface, includes a base member and a hydrophilic polymer layer. The hydrophilic polymer layer contains a hydrophilic polymer having a hydroxy group and an amide group. The hydrophilic polymer layer is provided on at least a part of the inside surface and/or on at least a part of the outside surface.

Abstract: The disclosure relates to embodiments of an apparatus for producing polymer composite panels. The polymer composite panels include one or more layers of a polymeric matrix having discontinuous fibers embedded therein. The apparatus has a frame, a deposition bed, and a deposition head configured to move relative to the frame and over the deposition bed. The deposition head includes at least one extruder and a nozzle array. The extruder is configured to force the polymeric matrix and discontinuous fibers through the nozzle array and onto the deposition bed. The deposition head is configured to deposit an entire layer of a polymer composite panel on the deposition bed in a single pass so that the discontinuous fibers are oriented in the direction of the single pass. The disclosure also relates to embodiments of a method of forming a polymer composite panel and to embodiments of a polymer composite panel.

Abstract: A container having a canister can be configured to retain a volume of liquid. The canister can be sealed by a lid structure, and the lid structure can have a spout opening. The spout opening may be sealed by a removably-coupled cap. Further, the cap may have a magnetic top surface configured to magnetically couple to a recess on the top surface of the lid for temporary storage of the cap when manually removed from the spout opening.

Abstract: A bag may include an outer shell including an opening, a front, and a back, a bottom inner liner wherein the bottom inner liner is affixed to a lower portion of the outer shell, a base outer shell wherein the base outer shell is positioned on a bottom of the bag, a storage compartment, a top binding positioned around an upper circumference of the opening, an inner pocket positioned in an interior of the storage compartment, and a plurality of straps is disclosed.

Abstract: In one aspect, a pressing unit is provided, comprising: a mold and a plunger, and a coating configured on at least one of: the surface of the mold and/or the surface of the plunger, where the coating is configured adjacent to the areas where molten or hot glass or glass ceramic touches; wherein the coating comprises: a mold release coating, configured as the gob-contacting surface, wherein the mold release coating comprises: at least two solid lubricants selected from tungsten disulfide, boron nitride, glassy carbon and graphite; and a thermal barrier coating comprising barrier material components and an organo-silica binder.

Abstract: The present invention relates to bi-functional compounds which function to recruit endogenous proteins to an E3 ubiquitin ligase for degradation, and methods for using same. More specifically, the present disclosure provides specific proteolysis targeting chimera (PROTAC) molecules which find utility as modulators of targeted ubiquitination of a variety of polypeptides and other proteins, in particular the androgen receptor of a slice variant of AR which lacks the LBD, labelled as AR-V7, which are then degraded and/or otherwise inhibited by the compounds as described herein.

Abstract: A portable container and container assembly provides a durable, functional and simple carry-all solution for dry and wet provisions, goods and gear. Exemplary features of various embodiments include one or more of an overmolded pad on the bottom of the container, a removable handle incorporating a releasable retaining structure, a lid that seals within the container cavity and is flush with the outer periphery of the container sidewall and/or has a cellular internal reinforcing structure, a skirt extending around the sidewall that is integral with handle mounts for the handle and/or provides a connection point for external components, and a drop-in tray with a collapsible handle.

Abstract: The present invention relates to bi-functional compounds which function to recruit endogenous proteins to an E3 ubiquitin ligase for degradation, and methods for using same. More specifically, the present disclosure provides specific proteolysis targeting chimera (PROTAC) molecules which find utility as modulators of targeted ubiquitination of a variety of polypeptides and other proteins, in particular the androgen receptor of a slice variant of AR which lacks the LBD, labelled as AR-V7, which are then degraded and/or otherwise inhibited by the compounds as described herein.

Abstract: The present invention relates to bi-functional compounds which function to recruit endogenous proteins to an E3 ubiquitin ligase for degradation, and methods for using same. More specifically, the present disclosure provides specific proteolysis targeting chimera (PROTAC) molecules which find utility as modulators of targeted ubiquitination of a variety of polypeptides and other proteins, in particular the androgen receptor of a slice variant of AR which lacks the LBD, labelled as AR-V7, which are then degraded and/or otherwise inhibited by the compounds as described herein.

Abstract: An example lid assembly may include a lid and a slider. The lid may further include a guide channel configured to receive the slider, and the channel may limit the lateral movement of the slider. The guide channel may further include a pair of air vents. The slider may be configured to slide along the lid, from a closed position where the slider covers the opening and to an opened position in which the slider uncovers the opening such that the contents of the container may be released. The slider may be configured to lock into place in both the closed position and the opened position.

Abstract: According to embodiments, a substantially coaxial arrangement of a camera, a light source, and an ultrasonic sensor can be positioned in an housing of a system that can be deployed from the tool port of a standard bronchoscope. Illumination from the light source facilitates positioning of the system by an operator using information from the camera. The ultrasonic system can determine when an object to be biopsied is adjacent to a biopsy needle.

Abstract: An apparatus may include a shell defining a first side and a second side, a storage compartment, an opening configured to provide access to the storage compartment, the opening including a closure device, a first carry strap and a second carry strap, a plurality of reinforcement patches in which the first carry strap and the second carry strap are connected to a portion of the plurality of reinforcement patches, a base, and a strip along a bottom of the apparatus configured to provide reinforcement.

Abstract: A container having a canister can be configured to retain a volume of liquid. The canister can be sealed by a lid structure, and the lid structure can have a spout opening. The spout opening may be sealed by a removably-coupled cap. Further, the cap may have a magnetic top surface configured to magnetically couple to a recess on the top surface of the lid for temporary storage of the cap when manually removed from the spout opening. Further, the lid structure may have one or more of an integrated anti-glug venting feature within the removable lid and cap or handle indexing.