Patents by Inventor Roy Lobb

Roy Lobb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER
    Publication number: 20180142035
    Abstract: Compositions, e.g., compositions comprising cellular therapeutics and/or protein therapeutics, and methods of using such compositions for treating cancer are described.
    Type: Application
    Filed: December 1, 2017
    Publication date: May 24, 2018
    Inventors: Roy Lobb, Paul Rennert
  • COMPOSITIONS AND METHODS FOR TUMOR TRANSDUCTION
    Publication number: 20180022821
    Abstract: The invention relates to cancer therapeutics, in particular, the system of making cancer cells more susceptible to effector cells by introduction of cellular therapy targets into the cancer cells.
    Type: Application
    Filed: August 7, 2017
    Publication date: January 25, 2018
    Inventors: Roy Lobb, Paul Rennert
  • COMPOSITIONS AND METHODS FOR TUMOR TRANSDUCTION
    Publication number: 20170260288
    Abstract: The invention relates to cancer therapeutics, in particular, the system of making cancer cells more susceptible to effector cells by introduction of cellular therapy targets into the cancer cells.
    Type: Application
    Filed: October 28, 2016
    Publication date: September 14, 2017
    Inventors: Roy Lobb, Paul Rennert
  • Protein Kinase Conjugates and Inhibitors
    Publication number: 20170174691
    Abstract: The invention relates to protein conjugates that contain a protein kinase containing a cysteine residue in the ATP binding site and an inhibitor that is covalently and irreversibly bonded to said cysteine residue, such that the activity of the protein kinase is irreversibly inhibited. The invention also relates to compounds that irreversibly inhibit protein kinases.
    Type: Application
    Filed: July 18, 2016
    Publication date: June 22, 2017
    Inventors: Juswinder Singh, Russell Colyn Petter, Deqiang Niu, Lixin Qiao, Arthur Kluge, Roy Lobb, Shomir Ghosh, Zhendong Zhu
  • Protein kinase conjugates and inhibitors
    Patent number: 9556426
    Abstract: The invention relates to protein conjugates that contain a protein kinase containing a cysteine residue in the ATP binding site and an inhibitor that is covalently and irreversibly bonded to said cysteine residue, such that the activity of the protein kinase is irreversibly inhibited. The invention also relates to compounds that irreversibly inhibit protein kinases.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: January 31, 2017
    Assignee: Celgene Avilomics Research, Inc.
    Inventors: Juswinder Singh, Russell Colyn Petter, Deqiang Niu, Lixin Qiao, Arthur Kluge, Roy Lobb, Shomir Ghosh, Zhendong Zhu
  • THERAPIES FOR CHRONIC RENAL FAILURE USING ONE OR MORE INTEGRIN ANTAGONISTS
    Publication number: 20140234299
    Abstract: The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of chronic renal failure, or at risk of a need for renal replacement therapy. The methods involve the administration of certain integrin antagonists.
    Type: Application
    Filed: January 17, 2014
    Publication date: August 21, 2014
    Applicants: Imperial College of Science, Technology and Medicine, Biogen Idec MA Inc.
    Inventors: Roy Lobb, Charles Pusey, Andrew Allen
  • Method for the treatment of inflammatory disorders
    Patent number: 8557240
    Abstract: A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: October 15, 2013
    Assignee: Biogen IDEC MA Inc.
    Inventors: Philip Gotwals, Antonin de Fougerolles, Roy Lobb, Victor E. Kotelianski
  • METHOD FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20120087925
    Abstract: A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
    Type: Application
    Filed: November 15, 2011
    Publication date: April 12, 2012
    Applicant: BIOGEN IDEC MA INC.
    Inventors: Philip Gotwals, Antonin de Fougerolles, Roy Lobb, Victor Kotelianski
  • Method for the treatment of inflammatory disorders
    Patent number: 8084031
    Abstract: A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
    Type: Grant
    Filed: November 11, 2008
    Date of Patent: December 27, 2011
    Assignee: Biogen Idec MA Inc.
    Inventors: Philip Gotwals, Antonin De Fougerolles, Roy Lobb, Victor Kotelianski
  • THERAPIES FOR CHRONIC RENAL FAILURE USING ONE OR MORE INTEGRIN ANTAGONISTS
    Publication number: 20110305686
    Abstract: The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of chronic renal failure, or at risk of a need for renal replacement therapy. The methods involve the administration of certain integrin antagonists.
    Type: Application
    Filed: March 16, 2011
    Publication date: December 15, 2011
    Inventors: Roy Lobb, Charles Pusey, Andrew Allen
  • Protein Kinase Conjugates and Inhibitors
    Publication number: 20110117073
    Abstract: The invention relates to protein conjugates that contain a protein kinase containg a cysteine residue in the ATP binding site and an inhibitor that is covalently and irreversibly bonded to said cysteine residue, such that the activity of the protein kinase is irreversibly inhibited. The invention also relates to compounds that irreversibly inhibit protein kinases.
    Type: Application
    Filed: September 15, 2010
    Publication date: May 19, 2011
    Applicant: Avila Therapeutics, Inc.
    Inventors: Juswinder Singh, Russell Colyn Petter, Deqiang Niu, Lixin Qiao, Arthur Kluge, Roy Lobb, Shomir Ghosh, Zhendong Zhu
  • METHOD FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20090324598
    Abstract: A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
    Type: Application
    Filed: November 11, 2008
    Publication date: December 31, 2009
    Applicant: Biogen Idec MA Inc.
    Inventors: Philip Gotwals, Antonin De Fougerolles, Roy Lobb, Victor Kotelianski
  • Method for the treatment of inflammatory disorders
    Patent number: 7462353
    Abstract: A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: December 9, 2008
    Assignee: Biogen Idec MA Inc.
    Inventors: Philip Gotwals, Antonin DeFougerolles, Roy Lobb, Victor Koteliansky
  • Treatment for inflammatory bowel disease
    Publication number: 20070253902
    Abstract: A method for the treatment of inflammatory bowel disease (IBD) is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a surface molecule expressed on most types of white blood cells and involved in leukocyte adhesion to endothelium and other tissus in the gut.
    Type: Application
    Filed: December 6, 2006
    Publication date: November 1, 2007
    Inventors: Roy Lobb, Linda Burkly
  • Recombinant anti-VLA4 antibody molecules
    Publication number: 20070248598
    Abstract: The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In addition, the humanized recombinant anti-VLA-4 antibodies disclosed can be useful in methods of diagnosing and localizing sites of inflammation.
    Type: Application
    Filed: November 29, 2006
    Publication date: October 25, 2007
    Applicant: Biogen Idec MA Inc.
    Inventors: Roy Lobb, Frank Carr, Philip Tempest
  • Endothelial cell-leukocyte adhesion molecules (ELAMs) and molecules involved in leukocyte adhesion (MILAs)
    Publication number: 20070149769
    Abstract: Antibodies specific for ELAMs are disclosed.
    Type: Application
    Filed: June 6, 2006
    Publication date: June 28, 2007
    Inventors: Catherine Hession, Roy Lobb, Susan Goelz, Laurelee Osborn, Christopher Benjamin, Margaret Rosa
  • Therapies for renal failure using interferon-beta
    Publication number: 20070025965
    Abstract: The present invention provides methods for the treatment, and pharmaceuticals for the use in the treatment, of mammalian subjects having, or at risk of developing, glomerulonephritis or chronic renal failure. The methods involve the administration of IFN-? therapeutics.
    Type: Application
    Filed: July 17, 2003
    Publication date: February 1, 2007
    Inventor: Roy Lobb
  • Methods of treating central nervous system ischemic or hemorrhagic injury using anti alpha4 integrin antagonists
    Publication number: 20060115473
    Abstract: Methods of, and compositions for, treating central nervous system injury with an antagonist of an alpha4 subunit containing integrin are described.
    Type: Application
    Filed: August 29, 2005
    Publication date: June 1, 2006
    Inventors: Jane Relton, Roy Lobb, Eric Whalley, Steven Adams
  • Treatment for asthma
    Publication number: 20060013808
    Abstract: A method for the treatment of asthma is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a protein expressed on the surface of certain leukocytes such as eosinophils.
    Type: Application
    Filed: June 28, 2005
    Publication date: January 19, 2006
    Inventors: Roy Lobb, Linda Burkly
  • Method for the treatment of inflammatory disorders
    Patent number: 6955810
    Abstract: A method for the treatment of inflammatory disorders is disclosed, particularly the treatment of arthritis. The method comprises the administration of a function blocking antibody which is capable of binding an epitope of VLA-1.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: October 18, 2005
    Assignee: Biogen Idec, Inc.
    Inventors: Philip Gotwals, Antonin DeFougerolles, Roy Lobb, Victor Kotelianski