Patents by Inventor Roy Ogle
Roy Ogle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260053979Abstract: A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.Type: ApplicationFiled: April 7, 2025Publication date: February 26, 2026Inventors: Michael Francis, Roy Ogle
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Patent number: 12290612Abstract: A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.Type: GrantFiled: August 10, 2020Date of Patent: May 6, 2025Assignee: LifeNet HealthInventors: Michael Francis, Roy Ogle
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Patent number: 11318227Abstract: A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.Type: GrantFiled: July 25, 2018Date of Patent: May 3, 2022Inventors: Michael Francis, Roy Ogle
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Publication number: 20200368386Abstract: A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.Type: ApplicationFiled: August 10, 2020Publication date: November 26, 2020Inventors: Michael Francis, Roy Ogle
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Publication number: 20190167842Abstract: A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.Type: ApplicationFiled: July 25, 2018Publication date: June 6, 2019Inventors: Michael Francis, Roy Ogle
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Patent number: 10220116Abstract: The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same. The invention further relates to bone matrix scaffolds comprising one or more bone matrix nanofibers, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells and promoting differentiation of stem cells using the same.Type: GrantFiled: August 16, 2017Date of Patent: March 5, 2019Assignee: Lifenet HealthInventors: Michael Francis, Roy Ogle
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Patent number: 10137223Abstract: A scaffold comprising an aligned fiber. The invention further relates to a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180? apart from each other. Methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.Type: GrantFiled: March 13, 2014Date of Patent: November 27, 2018Assignee: LifeNet HealthInventors: Michael Francis, Roy Ogle
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Publication number: 20170368227Abstract: The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same. The invention further relates to bone matrix scaffolds comprising one or more bone matrix nanofibers, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells and promoting differentiation of stem cells using the same.Type: ApplicationFiled: August 16, 2017Publication date: December 28, 2017Inventors: Michael Francis, Roy Ogle
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Patent number: 9775931Abstract: The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same. The invention further relates to bone matrix scaffolds comprising one or more bone matrix nanofibers, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells and promoting differentiation of stem cells using the same.Type: GrantFiled: April 26, 2016Date of Patent: October 3, 2017Assignee: LifeNet HealthInventors: Michael Francis, Roy Ogle
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Publication number: 20160317709Abstract: The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same. The invention further relates to bone matrix scaffolds comprising one or more bone matrix nanofibers, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells and promoting differentiation of stem cells using the same.Type: ApplicationFiled: April 26, 2016Publication date: November 3, 2016Inventors: Michael Francis, Roy Ogle
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Patent number: 9345810Abstract: The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same. The invention further relates to bone matrix scaffolds comprising one or more bone matrix nanofibers, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells and promoting differentiation of stem cells using the same.Type: GrantFiled: February 7, 2013Date of Patent: May 24, 2016Assignee: LifeNet HealthInventors: Michael Francis, Roy Ogle
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Publication number: 20160022865Abstract: A scaffold comprising an aligned fiber. The invention further relates to a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180? apart from each other. Methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.Type: ApplicationFiled: March 13, 2014Publication date: January 28, 2016Applicant: LIFENET HEALTHInventors: Michael FRANCIS, Roy OGLE
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Publication number: 20150010607Abstract: The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same. The invention further relates to bone matrix scaffolds comprising one or more bone matrix nanofibers, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells and promoting differentiation of stem cells using the same.Type: ApplicationFiled: February 7, 2013Publication date: January 8, 2015Inventors: Michael Francis, Roy Ogle
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Publication number: 20130345140Abstract: The invention relates to cell support compositions comprising a basement membrane extract isolated from cardiac or smooth muscle. The invention also relates to methods of using the cell support compositions for supporting cellular functions.Type: ApplicationFiled: August 25, 2011Publication date: December 26, 2013Applicant: LifeNet HealthInventor: Roy Ogle
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Publication number: 20080026462Abstract: Described herein are stem cells derived from the meninges; specifically, the dura mater, pia mater or arachnoid mater. Methods for isolating, differentiating and explanting these cells are described, as well. In particular embodiments, the stem cells of the present invention are differentiated into nerve cells, bone cells, cartilage cells and Schwann cells. The stem cells of the invention can be taken from a small biopsy, and rapidly expanded to large populations of cells using specially defined media that maintain their undifferentiated state. Use of the stem cells of the present invention in biomedical applications is also described.Type: ApplicationFiled: August 22, 2007Publication date: January 31, 2008Inventors: Roy Ogle, Sunil Tholpady