Abstract: The present invention includes novel methods and compositions for targeting tau aggregates, or components thereof. In one specific embodiment, the invention include the novel use of polyserine repeat sequences, and/or serine-rich sequences, which may be coupled with a heterologous peptide, to target tau aggregates, or components thereof, and thereby localize the heterologous peptide to the tau aggregate.

Abstract: The instant disclosure relates to a farrier hoof stand apparatus that includes a base, a vertical rise adjuster centrally and orthogonally affixed to the base. A plurality of buttresses are each affixed to the base and vertical rise adjuster (“VRA”). A stall jack is slidably positioned over the VRA opposite the base. A cradle is demountably positioned on the stall jack. A plurality of elongated tool holders are each affixed to the stall jack. A pin fastener is demountably coupled to the VRA and the stall jack. A plurality of magnets are each peripherally affixed to the base. The stall jack includes an anvil, an orifice positioned on the anvil, and a post affixed to the anvil. The post is slidably positioned over the VRA. The base is square and substantially planar. The plurality of elongated tool holders are each angularly affixed to the post opposite each other.

Abstract: The instant disclosure relates to a farrier hoof stand apparatus that includes a base, a vertical rise adjuster centrally and orthogonally affixed to the base. A plurality of buttresses are each affixed to the base and vertical rise adjuster (“VRA”). A stall jack is slidably positioned over the VRA opposite the base. A cradle is demountably positioned on the stall jack. A plurality of elongated tool holders are each affixed to the stall jack. A pin fastener is demountably coupled to the VRA and the stall jack. A plurality of magnets are each peripherally affixed to the base. The stall jack includes an anvil, an orifice positioned on the anvil, and a post affixed to the anvil. The post is slidably positioned over the VRA. The base is square and substantially planar. The plurality of elongated tool holders are each angularly affixed to the post opposite each other.

Abstract: A disposable meter for testing the level of total dissolved solids in a water source and a method of testing the concentration of total dissolved solids are herein disclosed. The disposable meter may include a body with at least water resistant properties, a first indicator, the energization of which is indicative of a threshold level measured total dissolved solids, a pair of electrodes wherein energization passing between the pair of electrodes completes a circuit, and circuitry disposed within the body connected to the first indicator and the pair of electrodes. The circuitry may be configured to commence energization to pass between the pair of electrodes, measure the conductivity of the water between the pair of electrodes, and energize the first indicator if the measured conductivity value exceeds a predetermined threshold value.

Abstract: A disposable meter for testing the level of total dissolved solids in a water source and a method of testing the concentration of total dissolved solids are herein disclosed. The disposable meter may include a body with at least water resistant properties, a first indicator, the energization of which is indicative of a threshold level measured total dissolved solids, a pair of electrodes wherein energization passing between the pair of electrodes completes a circuit, and circuitry disposed within the body connected to the first indicator and the pair of electrodes. The circuitry may be configured to commence energization to pass between the pair of electrodes, measure the conductivity of the water between the pair of electrodes, and energize the first indicator if the measured conductivity value exceeds a predetermined threshold value.

Abstract: An improved intimate cardable fiber blend containing polytetrafluoroethylene fibers, dual glass fibers and polyphenylene sulfide fibers and a filtration felt including a needled batt of the intimate cardable fiber blend made by mechanically blending the polyphenylene sulfide fibers and glass fibers with polytetrafluoroethylene fibers, carding the blend to form a nonwoven batt and needling the batt to provide a felt.

Abstract: A method for preparing meat products and a chip in a convenient and ready-to-eat form in a manner that is intended at preserving the meat flavor once part of the chip. The present invention provides an edible chip arrangement or similar foodstuff which includes a grain product such as wheat, rice, or corn, as well as a meat product sandwiched between at least two chips. The meat product can be a variety of types of meats, including, for example, pepperoni and beef jerky.

Abstract: A method for determining the function of a test protein is disclosed. In a preferred embodiment, this method comprises the steps of fusing a test protein to an RNA-binding protein and exposing the fusion protein to recombinant reporter mRNA molecule that comprises a binding site for the RNA-binding protein in the 3′ untranslated region. One then observes the properties of reporter mRNA and correlates the reporter properties with test protein function.

Abstract: A method for determining the function of a test protein is disclosed. In a preferred embodiment, this method comprises the steps of fusing a test protein to an RNA-binding protein and exposing the fusion protein to recombinant reporter mRNA molecule that comprises a binding site for the RNA-binding protein in the 3' untranslated region. One then observes the properties of reporter mRNA and correlates the reporter properties with test protein function.

Abstract: A bath for use by elderly or disabled persons, comprising a bath tub, and a seat for a user which seat is movable between a lower, bathing position and an upper position for the user to mount and dismount, wherein the seat is tiltable between a generally upright mode for use when in the upper position for mounting and dismounting and a reclined mode for use when in the lower position for bathing.

Abstract: An invalid hoist comprises a pivoted jib (3) for carrying an under arm-sling (13), which is arranged when pivoted to lift a user from a sitting position to a standing position and vice versa. The hoist includes knee engaging means (5) and is preferably mounted on a movable chassis (1). The arrangement is such that the movement of the user's upper body from a sitting position to a standing position always involves a substantial forward component. In preferred embodiments, this is achieved by locating the pivot (15) at substantially the level of a user's waist, by having a jib (3) which is at least twice the length of the distance between the knee joint and the hip joint, and by spacing the pivot (15) backwardly from the knee engaging means (5).