Patents by Inventor Roy RABINOWITZ

Roy RABINOWITZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT FOR PARKINSONIAN PATIENTS WITH MUTATIONS IN THE LRRK2 GENE
    Publication number: 20200370040
    Abstract: A method of treating Parkinson's Disease (PD) characterized by the presence of a mutant allele of leucine-rich repeat kinase 2 (LRRK2) gene in a subject is disclosed. The method comprises administering to the subject a CRISPR-Cas system guide RNA (gRNA) which specifically binds to the mutant allele of said leucine-rich repeat kinase 2 (LRRK2) gene and a CRISPR endonuclease, thereby treating the Parkinson's Disease (PD).
    Type: Application
    Filed: December 6, 2018
    Publication date: November 26, 2020
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Daniel OFFEN, Roy RABINOWITZ
  • COMPOSITIONS AND METHODS SPECIFICALLY TARGETING THE APOLIPOPROTEIN E4 (APOE4) AND USES THEREOF IN APOE4 ASSOCIATED CONDITIONS
    Publication number: 20200046853
    Abstract: The invention relates to improvement and therapy of neuronal conditions involving neurodegenerative, inflammatory and vascular conditions. More specifically, the invention provides compositions and methods for specific targeted elimination of apolipoprotein E4 (apoE4), and uses thereof in the treatment and prevention of ApoE4 associated conditions.
    Type: Application
    Filed: March 29, 2018
    Publication date: February 13, 2020
    Inventors: David OFFEN, Roy RABINOWITZ, Tall BEN-ZUR, Daniel MICHAELSON