Abstract: An endoscopic clip apparatus includes a clip sleeve defining an interior passage along a longitudinal axis and having a distal end with a plurality of openings defined in the distal end. A clip including a plurality of arms is disposed in the clip sleeve, and each arm includes a distal tip extending from the clip sleeve through one of the plurality of openings. Each arm includes a convex curved section oriented away from the longitudinal axis. The clip sleeve and clip are axially moveable relative to each other such that when the clip sleeve travels over the convex curved section of each arm toward the distal tip of each arm, each arm is constrained by the clip sleeve and each distal tip advances toward the longitudinal axis to grasp tissue.

Abstract: An endoscopic clip apparatus includes a clip sleeve defining an interior passage along a longitudinal axis and having a distal end with a plurality of openings defined in the distal end. A clip including a plurality of arms is disposed in the clip sleeve, and each arm includes a distal tip extending from the clip sleeve through one of the plurality of openings. Each arm includes a convex curved section oriented away from the longitudinal axis. The clip sleeve and clip are axially moveable relative to each other such that when the clip sleeve travels over the convex curved section of each arm toward the distal tip of each arm, each arm is constrained by the clip sleeve and each distal tip advances toward the longitudinal axis to grasp tissue.

Abstract: Endoscopic devices and methods used for fastening multiple tissue layers, such as, for example, an endoscopic fundoplication procedure, are disclosed. The device may include, for example, an elongated tubular member having a proximal end for extending outside of the body and a distal end for positioning proximate the multiple tissue layers, a grasper configured for positioning proximate the distal end of the tubular member and for grasping at least one of the multiple tissue layers, a device coupled to the distal end of the tubular member for folding the multiple tissue layers together, a tissue fastener configured to be inserted into the tissue layers to hold the tissue layers together, and a fastener head for inserting the tissue fastener into the tissue layers.

Abstract: Endoscopic instrument assemblies and methods for making and using the same. An example endoscopic instrument assembly includes an endoscope having a working channel and an endoscopic instrument slidably disposed in the working channel. The inside surface of the working channel and the outside surface of the endoscopic instrument each have a non-circular cross-sectional shape along at least a portion of their respective lengths.

Abstract: Endoscopic devices and methods used for fastening multiple tissue layers, such as, for example, an endoscopic fundoplication procedure, are disclosed. The device may include, for example, an elongated tubular member having a proximal end for extending outside of the body and a distal end for positioning proximate the multiple tissue layers, a grasper configured for positioning proximate the distal end of the tubular member and for grasping at least one of the multiple tissue layers, a device coupled to the distal end of the tubular member for folding the multiple tissue layers together, a tissue fastener configured to be inserted into the tissue layers to hold the tissue layers together, and a fastener head for inserting the tissue fastener into the tissue layers.

Abstract: Aspects and embodiments directed to cervical seals are disclosed. In one embodiment, a cervical seal having adjustable length comprises a first portion and a second portion, each configured to receive an elongated central member, a length of the cervical seal corresponding to a distance between the first portion and the second portion. The cervical seal further comprises a membrane coupled to the first portion and the second portion and extending along the length of the cervical seal, wherein the first portion is movable from a first position along the elongated central member to a second position along the elongated central member, so as to change the length of the cervical seal and the membrane is configured so that a radial profile of the membrane increases in response to increasing the length of the cervical seal, so as to provide a conformable cervical seal.

Abstract: Surgical tissue fasteners and related deployment systems and methods are disclosed. A tissue fastener used to join multiple tissue layers includes a first member, a second member, and a connecting member connecting the first and second members. In some embodiments, the first and second members are configured to expand from a delivered state to a deployed state in which the fastener secures the tissue layers together. Other tissue fastener embodiments include means for applying a substantially constant force on the tissue layers and/or means for adjusting a length of the connecting member between the first and second members.

Abstract: Surgical tissue fasteners and related deployment systems and methods are disclosed. A tissue fastener used to join multiple tissue layers includes a first member, a second member, and a connecting member connecting the first and second members. In some embodiments, the first and second members are configured to expand from a delivered state to a deployed state in which the fastener secures the tissue layers together. In other tissue fastener embodiments the connecting member has an elastic compressive spring force for applying a substantially constant force on the tissue layers for adjusting a length of the connecting member between the first and second members.

Abstract: A control handle for use with a steerable endoscopic device. The endoscopic device having a pair of control wires to effect steering. The control handle includes a steering mechanism that includes an actuator, such as a control knob, drivingly connected to a drive member, such as a sprocket or drive gear. To transmit force from the drive member to the control wires, a length of transmission structure, such as bead chain, is connected to the proximal ends of the control wires and is engaged with the drive member. In one embodiment, a single-use endoscope may be provided, which includes a control handle, a steerable endoscopic device, and a umbilical cord or communications conduit for functionally connecting the control handle to a control cabinet of an endoscopic imaging system.

Abstract: A control handle for use with a steerable endoscopic device. The endoscopic device having a pair of control wires to effect steering. The control handle includes a steering mechanism that includes an actuator, such as a control knob, drivingly connected to a drive member, such as a sprocket or drive gear. To transmit force from the drive member to the control wires, a length of transmission structure, such as bead chain, is connected to the proximal ends of the control wires and is engaged with the drive member. In one embodiment, a single-use endoscope may be provided, which includes a control handle, a steerable endoscopic device, and a umbilical cord or communications conduit for functionally connecting the control handle to a control cabinet of an endoscopic imaging system.

Abstract: A control handle for use with a steerable endoscopic device. The endoscopic device having a pair of control wires to effect steering. The control handle includes a steering mechanism that includes an actuator, such as a control knob, drivingly connected to a drive member, such as a sprocket or drive gear. To transmit force from the drive member to the control wires, a length of transmission structure, such as bead chain, is connected to the proximal ends of the control wires and is engaged with the drive member. In one embodiment, a single-use endoscope may be provided, which includes a control handle, a steerable endoscopic device, and a umbilical cord or communications conduit for functionally connecting the control handle to a control cabinet of an endoscopic imaging system.

Abstract: Surgical tissue fasteners and related deployment systems and methods are disclosed. A tissue fastener used to join multiple tissue layers includes a first member, a second member, and a connecting member connecting the first and second members. In some embodiments, the first and second members are configured to expand from a delivered state to a deployed state in which the fastener secures the tissue layers together. Other tissue fastener embodiments include means for applying a substantially constant force on the tissue layers and/or means for adjusting a length of the connecting member between the first and second members.

Abstract: A medical device includes a handle and a shaft having a working channel. A biopsy port at the exterior of the handle provides a path for instruments leading to the working channel. A conduit that runs through the handle for supplying fluids is also provided a path to the working channel. As compared between the path from the biopsy port to the working channel and the path from the conduit to the working channel, the path from the biopsy port to the working channel is the more direct path of the two.

Abstract: A steerable shaft of a medical instrument is steered by one or more control cables. The control cables are in contact with a steering system tension control device that reduces the tension in the control cables caused by bends in the shaft.

Abstract: Endoscopic instrument assemblies and methods for making and using the same. An example endoscopic instrument assembly includes an endoscope having a working channel and an endoscopic instrument slidably disposed in the working channel. The inside surface of the working channel and the outside surface of the endoscopic instrument each have a non-circular cross-sectional shape along at least a portion of their respective lengths.

Abstract: An apparatus and a method for performing a medical procedure is disclosed. The apparatus includes a positioning system and a resection device disposed within the positioning system. The positioning system includes an imaging device, a video processor coupled to the imaging device, a computer coupled to the video processor, and a video display coupled to the computer. The method includes the steps of creating an image of a lesion within a patient's body on an imaging device. Data representative of the lesion image is processed by a video processor. Tissue margins around the lesion are defined by a processor based on the processed data representative of the lesion image and a resection device is operated during a resection procedure within the patient's body based upon the defined tissue margins.

Abstract: An apparatus and a method for performing a medical procedure is disclosed. In an embodiment for an apparatus of the present invention, the apparatus includes a positioning system and a resection device disposed within the positioning system. The positioning system includes an imaging device, a video processor coupled to the imaging device, a computer coupled to the video processor, and a video display coupled to the computer. In an embodiment for a method of practicing the present invention, the method includes the steps of creating an image of a lesion within a patient's body on an imaging device. Data representative of the lesion image is processed by a video processor. Tissue margins around the lesion are defined by a processor based on the processed data representative of the lesion image and a resection device is operated during a resection procedure within the patient's body based upon the defined tissue margins.

Abstract: Endoscopic devices and methods used for fastening multiple tissue layers, such as, for example, an endoscopic fundoplication procedure, are disclosed. The device may include, for example, an elongated tubular member having a proximal end for extending outside of the body and a distal end for positioning proximate the multiple tissue layers, a grasper configured for positioning proximate the distal end of the tubular member and for grasping at least one of the multiple tissue layers, a device coupled to the distal end of the tubular member for folding the multiple tissue layers together, a tissue fastener configured to be inserted into the tissue layers to hold the tissue layers together, and a fastener head for inserting the tissue fastener into the tissue layers.

Abstract: Describeed is a full-thickness resection system which includes a control unit coupled to a proximal end of a flexible endoscope. The control unit remains outside of a body when the stapling head is in an operative position within a body lumen. The control unit includes (i) an anvil actuator coupled to an anvil in the stapling head, actuation of the anvil actuator moves the anvil axially relative to a stapling mechanism in the stapling head to compress a folded full-thickness portion of lumenal tissue between the anvil and the stapling mechanism. In addition, the control unit includes (ii) a stapler actuator coupled to the stapling mechanism in the stapling head, actuation of the stapler actuator causing the stapling mechanism to drive staples through the folded lumenal tissue against the anvil.

Abstract: Surgical devices and methods used for invaginating tissue during, for example, an endoscopic fundoplication procedure, are disclosed. The device includes an elongated tube having a proximal end configured to extend outside of the body and a distal end configured to extend proximate the tissue to be invaginated, and a distal member coupled to the distal end of the tube. The distal member is configured to hold or grasp the tissue to be invaginated. The devices may include a protective distal sleeve.