Patents by Inventor Roy Wendell WARE

Roy Wendell WARE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
    Patent number: 11912667
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: February 27, 2024
    Assignee: EMERGENT BIODEFENSE OPERATIONS LANSING LLC
    Inventors: Roy Wendell Ware, Aaron Leigh Downey
  • MORPHIC FORMS OF HEXADECYLOXYPROPYL-PHOSPHONATE ESTERS AND METHODS OF SYNTHESIS THEREOF
    Publication number: 20220144782
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Application
    Filed: June 16, 2021
    Publication date: May 12, 2022
    Inventors: Roy Wendell WARE, Aaron Leigh DOWNEY
  • Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
    Patent number: 11066373
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: July 20, 2021
    Assignee: Chimerix, Inc.
    Inventors: Roy Wendell Ware, Aaron Leigh Downey
  • MORPHIC FORMS OF HEXADECYLOXYPROPYL-PHOSPHONATE ESTERS AND METHODS OF SYNTHESIS THEREOF
    Publication number: 20200095208
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Application
    Filed: October 11, 2019
    Publication date: March 26, 2020
    Inventors: Roy Wendell WARE, Aaron Leigh DOWNEY
  • Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
    Patent number: 10487061
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: November 26, 2019
    Assignee: Chimerix, Inc.
    Inventors: Roy Wendell Ware, Aaron Leigh Downey
  • MORPHIC FORMS OF HEXADECYLOXYPROPYL-PHOSPHONATE ESTERS AND METHODS OF SYNTHESIS THEREOF
    Publication number: 20190016687
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Application
    Filed: September 19, 2018
    Publication date: January 17, 2019
    Inventors: Roy Wendell WARE, Aaron Leigh DOWNEY
  • Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
    Patent number: 10112909
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: October 30, 2018
    Assignee: Chimerix, Inc.
    Inventors: Roy Wendell Ware, Aaron Leigh Downey
  • MORPHIC FORMS OF HEXADECYLOXYPROPYL-PHOSPHONATE ESTERS AND METHODS OF SYNTHESIS THEREOF
    Publication number: 20180086721
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Application
    Filed: December 1, 2017
    Publication date: March 29, 2018
    Inventors: Roy Wendell Ware, Aaron Leigh Downey
  • Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
    Patent number: 9862687
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: January 9, 2018
    Assignee: Chimerix, Inc.
    Inventors: Roy Wendell Ware, Jr., Aaron Leigh Downey
  • FORMULATIONS OF BRINCIDOFOVIR
    Publication number: 20170368082
    Abstract: Disclosed are formulations comprising brincidofovir. The formulations can be intravenous formulations. The formulations can be used in cases where a subject experiences gastrointestinal issues in response to oral administration of brincidofovir. The formulations can also be used in cases where oral administration of drug is not possible due to underlying conditions or concern around inadequate oral absorption.
    Type: Application
    Filed: June 28, 2017
    Publication date: December 28, 2017
    Inventors: Roy Wendell WARE, Mohammed Anowrul KABIR, Odin Johann Naderer, Irma Marisa GROSSI
  • MORPHIC FORMS OF HEXADECYLOXYPROPYL-PHOSPHONATE ESTERS AND METHODS OF SYNTHESIS THEREOF
    Publication number: 20160264531
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Application
    Filed: May 20, 2016
    Publication date: September 15, 2016
    Inventors: Roy Wendell Ware, JR., Aaron Leigh Downey
  • Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
    Patent number: 9371344
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: June 21, 2016
    Assignee: Chimerix, Inc.
    Inventors: Roy Wendell Ware, Jr., Aaron Leigh Downey
  • MORPHIC FORMS OF HEXADECYLOXYPROPYL-PHOSPHONATE ESTERS AND METHODS OF SYNTHESIS THEREOF
    Publication number: 20150210724
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Application
    Filed: January 23, 2015
    Publication date: July 30, 2015
    Inventors: Roy Wendell Ware, JR., Aaron Leigh Downey
  • Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
    Patent number: 8962829
    Abstract: The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: February 24, 2015
    Assignee: Chimerix, Inc.
    Inventors: Roy Wendell Ware, Jr., Aaron Leigh Downey