Abstract: A case is provided for holding one or more contact lenses. The case is configured to receive an inner pod, and the case includes an upper part and a lower part. The upper part is structured to move relative to the lower part from an open configuration wherein the upper and lower parts are at least partially separated to a closed configuration wherein the upper and lower parts are together. The upper part is also structured to move relative to the lower part from a disengaged position to an engaged position wherein, in the disengaged position, the case is movable between the open and closed configurations and in the engaged position, the case is locked in the closed configuration.

Abstract: A case is provided for holding one or more contact lenses. The case is configured to receive an inner pod, and the case includes an upper part and a lower part. The upper part is structured to move relative to the lower part from an open configuration wherein the upper and lower parts are at least partially separated to a closed configuration wherein the upper and lower parts are together. The upper part is also structured to move relative to the lower part from a disengaged position to an engaged position wherein, in the disengaged position, the case is movable between the open and closed configurations and in the engaged position, the case is locked in the closed configuration.

Abstract: A case is provided for holding one or more contact lenses. The case is configured to receive an inner pod, and the case includes an upper part and a lower part. The upper part is structured to move relative to the lower part from an open configuration wherein the upper and lower parts are at least partially separated to a closed configuration wherein the upper and lower parts are together. The upper part is also structured to move relative to the lower part from a disengaged position to an engaged position wherein, in the disengaged position, the case is movable between the open and closed configurations and in the engaged position, the case is locked in the closed configuration.

Abstract: A method for cleaning or disinfecting contact lenses comprising providing an ophthalmic composition comprising a quaternary polymer and a primary antimicrobial agent with the proviso that the quaternary polymer is not a cationic cellulosic polymer and is distinct from, and mutually exclusive of, the primary antimicrobial agent.

Abstract: This invention is directed to an aqueous composition and methods for clean lipid deposits on contact lenses. In particular, a combination of non-ionic surfactants, branched and/or straight poly(ethylene oxide-propylene oxide) (PEO-PPO) block copolymers having HLB value greater than or equal to 18, with an additional straight poly(ethylene oxide-propylene oxide) (PEO-PPO) block copolymers having HLB value less than or equal to 15, has been found to improve the lipid cleaning properties of an aqueous composition for contact lenses and prevent the overgrowth of harmful bacteria, yeast and molds without adversely affecting the comfort or safety in terms of the level of toxicity to eye tissue.

Abstract: The present invention is directed to a biguanide-containing disinfecting solutions effective in inactivating bacteria endospores on surfaces, air-borne or in water. The methods of using the present invention are directed to disinfecting endospore laden surfaces, air and water with the subject biguanide-containing solutions.

Abstract: The present invention includes in one embodiment a method for treating contact lenses. The method comprises placing the contact lens in the eye. An eye-drop solution is administered to the contact lens while worn in the eye. The eye-drop solution has a first amount of a surfactant. The contact lens is removed from the eye. The contact lens is cleaned with a conditioning solution, cleaning solution or multipurpose solution while the lens is removed from the eye. The cleaning solution or multipurpose solution has a second amount of a surfactant that is less than the first amount.

Abstract: A rigid gas permeable lens care composition. The composition includes a disinfecting amount of at least one biguanide antimicrobial agent and a straight chain polyether surfactant based upon PEO-PPO-PEO, PPO-PEO-PPO and combinations thereof. In one embodiment, the straight chain polyether surfactant has an HLB value of less than or equal to 15 and an average molecular weight value of between about 5000 and 7000. Preferably, no rubbing is required to disinfect the rigid gas permeable contact lenses is required. Methods of making and using the same are also described.

Abstract: The present invention relates to a novel eye-drop solution that has superior microbe and bacteria management properties. Regular use in the eye will prevent bacteria from being attached to the eye. Regular use of the eye-drops will also prevent growth of microbes in the eye. A patient that uses this invention can slow the progression of infection and growth of microbes between cleaning. For disposable contact lenses the antimicrobial management properties reduces the risk of infection during the extended wear period. In one embodiment, there is a method of treating contact lenses comprising administering to the lens an ophthalmically safe composition comprising an amount of antimicrobial agent that prevents growth of microbes in the eye but is a less than the minimum disinfecting amount.

Abstract: The present invention relates generally to the development of medical devices which show thermal reversible associations with similar polymer molecules contained in the majority of device care solutions. The thermal reversible association provides an enhanced interaction which leads to less bacterial adhesion and uptake on the device and sustained release of a conditioning agent.

Abstract: A medical device having a reduced affinity for bacterial attachment comprises a coating polymer that is attached to a surface thereof, the coating polymer providing a plurality of charges at a physiological condition. The medical device is produced by contacting the coating polymer with the medical device such that the coating polymer is attached thereto. The coating polymer may be attached to the medical device through an intermediate polymer.

Abstract: A method of treating a contact lens, and in some instances, a silicone hydrogel contact lens, in the eye of a wearer comprising i) applying to said contact lens and/or eye an ophthalmically compatible contact lens cleaning and/or hydrating and/or disinfecting solution; and ii) rubbing the eyelid associated with said eye over the contact lens for at least about one second.

Abstract: This invention is directed to an aqueous composition and methods for cleaning lipid deposits and/or prevention of lipid deposition on contact lenses. In particular, a combination of non-ionic surfactants, straight chain poly(ethylene oxide-propylene oxide-ethylene oxide) (PEO—PPO—PEO) block copolymers having HLB value greater than or equal to 18, with an additional straight chain poly(ethylene oxide-propylene oxide-ethylene oxide) (PEO—PPO—PEO) block copolymer having an HLB value less than or equal to 11, has been found to improve the lipid cleaning properties of an aqueous composition for contact lenses and prevent the overgrowth of harmful bacteria, yeast and molds without adversely affecting the comfort or safety in terms of the level of toxicity to eye tissue.

Abstract: This invention is directed to a method of treating a silicone hydrogel lens to cleaning lipid deposits thereon. The method comprises administering to the contact lens a solution comprising a first straight chain polyether surfactant. The first straight chain polyether surfactant has an HLB value that is a minimum of about 18. The second straight chain polyether surfactant has an HLB value that is a minimum of about 12 and a maximum of about 18. The second surfactant is present in an amount effective to improve the ability to remove lipids from a silicone hydrogel lens.

Abstract: This invention is directed to an aqueous composition and methods for clean lipid deposits on contact lenses. In particular, a combination of non-ionic surfactants, branched and/or straight poly(ethylene oxide-propylene oxide) (PEO-PPO) block copolymers having HLB value greater than or equal to 18, with an additional straight poly(ethylene oxide-propylene oxide) (PEO-PPO) block copolymers having HLB value less than or equal to 15, has been found to improve the lipid cleaning properties of an aqueous composition for contact lenses and prevent the overgrowth of harmful bacteria, yeast and molds without adversely affecting the comfort or safety in terms of the level of toxicity to eye tissue.

Abstract: Compositions for inhibiting attachment of microorganisms to the surface of biomaterials include a polyether, such as a poloxamer. The compositions are especially useful for treating contact lenses to prevent bacterial attachment to the lens.

Abstract: Novel compositions and methods for using lens care solutions made from the compositions to effectively clean and disinfect contact lenses. The methods for effectively cleaning and disinfecting contact lenses require no lens rubbing step and require no lens rinsing step.

Abstract: Ophthalmic compositions include a polycation material to enhance antimicrobial efficacy against bacteria such as E. coli. The compositions include eye drop and contact lens treating solutions. A preferred polycation material is cationic cellulose derivatives.

Abstract: A solution for soft, hydrogel contact lenses includes a polyether that is controllably released into an eye's tear film when the lens is worn. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved comfort, and/or reduced feeling of dryness from wearing contact lenses. The solution further includes a cationic polyelectrolyte.

Abstract: The use of compositions containing one or more antimicrobial agents with one or more trialkanolamine alkoxylate buffers to disinfect and/or preserve medical devices is described. Solutions containing one or more antimicrobial agents with one or more trialkanolamine alkoxylate buffers and methods of making and using the same are also described.