Patents by Inventor Roza Sawicka

Roza Sawicka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA VACCINE, METHOD OF INDUCING THE IMMUNE RESPONSE, METHOD OF IMMUNISATION, ANTIBODIES SPECIFICALLY RECOGNISING THE H5 HAEMAGGLUTININ OF AN INFLUENZA VIRUS AND USE OF THE DNA VACCINE
    Publication number: 20140255343
    Abstract: The object of the invention is a DNA vaccine, method of inducing the immune response, antibodies specifically recognising the haemagglutinin H5 of an influenza virus and application of the DNA vaccine. According to the invention, one or two-fold immunisation of hens with DNA vaccine containing a cDNA encoding the modified H5 haemagglutinin HA protein, i.e. with the deletion of the cleavage site between HA subunits (this provides for greater safety of the vaccines). Moreover, the encoding region of the HA is modified in such a way that protein production in the bird cells should achieve maximal yield. The main modification is codon optimisation for the hens and deletion of the site of proteolytic cleavage between subunits HA1 and HA2.
    Type: Application
    Filed: September 21, 2012
    Publication date: September 11, 2014
    Inventors: Agnieszka Sirko, Anna Gora-Sochacka, Wlodzimierz Zagorski-Ostoja, Anna Stachyra, Roza Sawicka, Boguslaw Szewczyk, Beata Gromadzka, Violetta Saczynska, Katarzyna Florys, Zenon Minta, Krzysztof Smietanka