Patents by Inventor Rozanne ARULANANDAM

Rozanne ARULANANDAM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION
    Publication number: 20220220101
    Abstract: Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Applicants: Ottawa Hospital Research Institute, University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • Compositions and methods for viral sensitization
    Patent number: 11339146
    Abstract: Provided are compounds of Formula (II) that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: May 24, 2022
    Assignee: Ottawa Hospital Research Institute and University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION
    Publication number: 20200354351
    Abstract: Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Application
    Filed: May 18, 2020
    Publication date: November 12, 2020
    Applicants: Ottawa Hospital Research Institute, University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • Compositions And Methods for Enhancing Production, Growth, Spread, or Oncolytic and Immunotherapeutic Efficacy of Interferon-Sensitive Viruses
    Publication number: 20200276253
    Abstract: Provided herein are fumaric and maleic acid-containing compounds, compositions comprising the same and methods for using such compounds to enhance production, growth, spread or titer of interferon-sensitive viruses in cells, particularly cancer and tumor cells. Also provided are methods of treating tumors or cancers in a subject by administering the compounds and compositions.
    Type: Application
    Filed: November 23, 2018
    Publication date: September 3, 2020
    Inventors: Jean-Simon Diallo, Mohammed Selman, Rozanne Arulanandam, Nicole Elise Forbes, Ramya Krishnan
  • Compositions and methods for viral sensitization
    Patent number: 10654839
    Abstract: Provided are compounds of Formula (II) that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: May 19, 2020
    Assignees: Ottawa Hospital Research Institute, University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • Compositions and methods for enhancing virus replication
    Patent number: 10604741
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: March 31, 2020
    Assignee: TURNSTONE LIMITED PARTNERSHIP
    Inventors: Carolina Solange Ilkow, Fabrice Le Boeuf, John Cameron Bell, Jean-Simon Diallo, Rozanne Arulanandam
  • Compositions and methods for enhancing virus replication
    Patent number: 10066214
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: September 4, 2018
    Assignee: Turnstone Limited Partnership
    Inventors: Carolina Solange Ilkow, Fabrice Le Boeuf, John Cameron Bell, Jean-Simon Diallo, Rozanne Arulanandam
  • COMPOSITIONS AND METHODS FOR ENHANCING VIRUS REPLICATION
    Publication number: 20180237753
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Application
    Filed: March 13, 2018
    Publication date: August 23, 2018
    Inventors: Carolina Solange ILKOW, Fabrice LE BOEUF, John Cameron BELL, Jean-Simon DIALLO, Rozanne ARULANANDAM
  • COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION
    Publication number: 20180112190
    Abstract: Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Application
    Filed: January 26, 2016
    Publication date: April 26, 2018
    Applicants: Ottawa Hospital Research Institute, University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • COMPOSITIONS AND METHODS FOR ENHANCING VIRUS REPLICATION
    Publication number: 20160130563
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 12, 2016
    Inventors: Carolina Solange ILKOW, Fabrice LE BOEUF, John Cameron BELL, Jean-Simon DIALLO, Rozanne ARULANANDAM