Patents by Inventor Ru Bai

Ru Bai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250064888
    Abstract: The invention provides compositions and methods for treating, reducing or preventing cytokine storm, for example, in connection with a viral infection (e.g., by SARS-CoV-2), drug treatment or therapy, trauma or an inflammatory disease, or a related disease and disorder.
    Type: Application
    Filed: January 20, 2023
    Publication date: February 27, 2025
    Inventors: Liping Liu, Ru Bai
  • Patent number: 11807672
    Abstract: The invention provides novel compounds, in particular peptide and peptide analogs, which exhibit functionalities useful for treating a variety of diseases and conditions, particularly diseases and conditions relating to diabetes. The compounds of the invention are also useful for treating impaired pancreatic function, treating metabolic diseases, ex vivo islet induction, expansion and proliferation for transplantation, increasing the survival of transplanted islets in vivo, promoting neuroprotection or nerve regeneration, promoting liver regeneration, and inhibiting inflammation.
    Type: Grant
    Filed: October 4, 2020
    Date of Patent: November 7, 2023
    Assignee: Shenzhen HighTide Biopharmaceutical, Ltd.
    Inventors: Liping Liu, Ru Bai
  • Publication number: 20230237228
    Abstract: A method of extracting parasitic parameters of a 3D IC is provided in the present invention, including steps of providing a 3D IC having multiple dies, merging respective layouts of the multiple dies into a common layout, creating a common LVS file and a common LPE file for those multiple dies based on the common layout, creating respective LVS files and respective LPE files for every die based on the respective layouts, creating a common netlist from the common LVS file and common LPE file, creating corresponding respective netlists from the respective LVS files and respective LPE files, merging the common netlist and respective netlists into a netlist, and extracting common parasitic parameters of the dies from the netlist.
    Type: Application
    Filed: March 10, 2022
    Publication date: July 27, 2023
    Applicant: UNITED MICROELECTRONICS CORP.
    Inventors: Chih-Yueh Lin, Chun-Yi Lin, Shang-Yu Liu, Jie-Ru Bai
  • Publication number: 20230116498
    Abstract: A concentration method and equipment. The concentration method includes the step of performing reverse osmosis concentration processing on raw milk by using a reverse osmosis membrane. The reverse osmosis concentration processing includes low-pressure reverse osmosis membrane concentration processing and high-pressure reverse osmosis membrane concentration processing, wherein in the low-pressure reverse osmosis membrane concentration processing, reverse osmosis concentration processing is performed on feeding materials by using a first predetermined pressure, and in the high-pressure reverse osmosis membrane concentration processing, the reverse osmosis concentration processing is performed on the feeding materials by using a second predetermined pressure, the first predetermined pressure being lower than the second predetermined pressure. The concentration equipment includes a temporary storage unit, a homogenizing unit, and a particular concentration unit.
    Type: Application
    Filed: March 24, 2020
    Publication date: April 13, 2023
    Applicant: INNER MONGOLIA MENGNIU DAIRY (GROUP) CO., LTD.
    Inventors: Weizhu YU, Jie ZHANG, Mengyuan FAN, Shengbo YU, Yonghong ZHANG, Xinghai LIU, Heqian DONG, Xianfeng REN, Hui WANG, Ru BAI, Hongli SHI, Wenting LIU, Xu WANG
  • Patent number: 11579209
    Abstract: A three-axis magnetic sensor apparatus is described that is processed together into a single chip, with high performance, low cost, as well as small size. The three-axis magnetic sensor apparatus include a substrate, a two-axis magnetic sensing structure and a single-axis sensing structure. The two-axis sensing magnetic structure consisting of two shielded Wheatstone bridge configurations in conjunction with an annular or semi annular magnetic flux-guiding structure, and the single-axis sensing structure consisting of a push-pull Wheatstone bridge in conjunction with a flux guide that is capable of generating a fringe field whose horizontal component is proportional to the vertical component of an external magnetic field. The two-axis magnetic sensing structure and the single-axis structure are processed together into a single chip, and can be used to measure respectively X, Y and Z components of external magnetic fields.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: February 14, 2023
    Inventors: Zhenghong Qian, Ru Bai
  • Patent number: 11534477
    Abstract: This invention discloses certain methods of treating acute pancreatitis and inflammatory pancreatic disease or condition. The disclosed peptides and analogs can significantly lower the elevated blood amylase and lipase levels caused by acute pancreatitis and pancreatic inflammation, reduce the degree of injury observed in pancreatic histopathology caused by pancreatitis, and significantly lower the mortality rate of acute pancreatitis.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: December 27, 2022
    Assignee: SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD.
    Inventors: Liping Liu, Ru Bai
  • Publication number: 20220348618
    Abstract: The invention provides peptides and analogs of INGAP and HIP peptides. The peptides and analogs can be used in methods for treating various diseases and conditions. Such diseases and conditions can include impaired pancreatic function, treating a metabolic disease, for example, diabetes, both type 1 and type 2 diabetes, islets induction, expansion and proliferation for transplantation, promoting neuroprotection or nerve regeneration, promoting liver regeneration or inhibiting inflammation.
    Type: Application
    Filed: May 18, 2022
    Publication date: November 3, 2022
    Inventors: Liping LIU, Ru Bai
  • Patent number: 11450503
    Abstract: An X-ray tube and an X-ray imaging device are disclosed. The X-ray tube comprises: a glass envelope; a cathode assembly, accommodated inside the glass envelope; and a core column structure, connected to the glass envelope and the cathode assembly, such that the cathode assembly is sealed inside the glass envelope. The core column structure comprises: a metal flat plate, wherein the cathode assembly is fixed to the metal flat plate; and a sealing bead, wherein the sealing bead is arranged in the metal flat plate, and an electrically conductive support rod connected to the cathode assembly passes through two ends of the sealing bead. The X-ray tube enables generated heat to be rapidly transferred to a cooling medium via thermally conductive metal to improve heat dissipation efficiency.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: September 20, 2022
    Assignee: Siemens Healthcare GmbH
    Inventors: Jing Ping Pan, Ru Bai Cheng
  • Publication number: 20220179239
    Abstract: A lens for slowing or preventing the development of myopia includes an optical portion and a peripheral portion surrounding the optical portion. The distribution of the refractive power of the optical portion is expressed by an exponential growth function. Assume that a specific condition is satisfied. The farther away from the center of the lens, the greater the change in the refractive power. Thus, a defocus area is formed to control and prevent eye myopia. Besides, the distribution of refractive power can provide a larger visible area in order to effectively avoid visual instability caused by lens sliding.
    Type: Application
    Filed: March 16, 2021
    Publication date: June 9, 2022
    Inventors: SHIH HONG CHU, CHAO CHENG CHEN, YA RU BAI, HUAN CHIU TSEN
  • Publication number: 20210356533
    Abstract: A three-axis magnetic sensor apparatus is described that is processed together into a single chip, with high performance, low cost, as well as small size. The three-axis magnetic sensor apparatus include a substrate, a two-axis magnetic sensing structure and a single-axis sensing structure. The two-axis sensing magnetic structure consisting of two shielded Wheatstone bridge configurations in conjunction with an annular or semi annular magnetic flux-guiding structure, and the single-axis sensing structure consisting of a push-pull Wheatstone bridge in conjunction with a flux guide that is capable of generating a fringe field whose horizontal component is proportional to the vertical component of an external magnetic field. The two-axis magnetic sensing structure and the single-axis structure are processed together into a single chip, and can be used to measure respectively X, Y and Z components of external magnetic fields.
    Type: Application
    Filed: October 22, 2018
    Publication date: November 18, 2021
    Inventors: Zhenghong Qian, Ru Bai
  • Publication number: 20210296073
    Abstract: An X-ray tube and an X-ray imaging device are disclosed. The X-ray tube comprises: a glass envelope; a cathode assembly, accommodated inside the glass envelope; and a core column structure, connected to the glass envelope and the cathode assembly, such that the cathode assembly is sealed inside the glass envelope. The core column structure comprises: a metal flat plate, wherein the cathode assembly is fixed to the metal flat plate; and a sealing bead, wherein the sealing bead is arranged in the metal flat plate, and an electrically conductive support rod connected to the cathode assembly passes through two ends of the sealing bead. The X-ray tube enables generated heat to be rapidly transferred to a cooling medium via thermally conductive metal to improve heat dissipation efficiency.
    Type: Application
    Filed: March 18, 2021
    Publication date: September 23, 2021
    Applicant: Siemens Healthcare GmbH
    Inventors: Jing Ping Pan, Ru Bai Cheng
  • Publication number: 20210122797
    Abstract: The invention provides novel compounds, in particular peptide and peptide analogs, which exhibit functionalities useful for treating a variety of diseases and conditions, particularly diseases and conditions relating to diabetes. The compounds of the invention are also useful for treating impaired pancreatic function, treating metabolic diseases, ex vivo islet induction, expansion and proliferation for transplantation, increasing the survival of transplanted islets in vivo, promoting neuroprotection or nerve regeneration, promoting liver regeneration, and inhibiting inflammation.
    Type: Application
    Filed: October 4, 2020
    Publication date: April 29, 2021
    Inventors: Liping LIU, Ru BAI
  • Publication number: 20210100871
    Abstract: This invention discloses certain method of use of peptides and their analogs in the treatment of acute pancreatitis. The disclosed peptides and analogs can significantly lower the elevated blood amylase and lipase levels caused by acute pancreatitis, reduce the degree of injury observed in pancreatic histopathology caused by pancreatitis, and significantly lower the mortality rate of acute pancreatitis.
    Type: Application
    Filed: September 3, 2020
    Publication date: April 8, 2021
    Inventors: Liping LIU, Ru BAI
  • Patent number: 10899815
    Abstract: The invention provides peptides and analogs of INGAP and HIP peptides. The peptides and analogs can be used in methods for treating various diseases and conditions. Such diseases and conditions can include impaired pancreatic function, treating a metabolic disease, for example, diabetes, both type 1 and type 2 diabetes, islets induction, expansion and proliferation for transplantation, promoting neuroprotection or nerve regeneration, promoting liver regeneration or inhibiting inflammation.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: January 26, 2021
    Assignee: Shenzhen HighTide Biopharmaceutical, Ltd.
    Inventors: Liping Liu, Ru Bai
  • Patent number: 10829527
    Abstract: The invention provides novel compounds, in particular peptide and peptide analogs, which exhibit functionalities useful for treating a variety of diseases and conditions, particularly diseases and conditions relating to diabetes. The compounds of the invention are also useful for treating impaired pancreatic function, treating metabolic diseases, ex vivo islet induction, expansion and proliferation for transplantation, increasing the survival of transplanted islets in vivo, promoting neuroprotection or nerve regeneration, promoting liver regeneration, and inhibiting inflammation.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: November 10, 2020
    Assignee: Shenzhen HighTide Biopharmaceutical, Ltd.
    Inventors: Liping Liu, Ru Bai
  • Publication number: 20200347106
    Abstract: The invention provides peptides and analogs of INGAP and HIP peptides. The peptides and analogs can be used in methods for treating various diseases and conditions. Such diseases and conditions can include impaired pancreatic function, treating a metabolic disease, for example, diabetes, both type 1 and type 2 diabetes, islets induction, expansion and proliferation for transplantation, promoting neuroprotection or nerve regeneration, promoting liver regeneration or inhibiting inflammation.
    Type: Application
    Filed: October 21, 2019
    Publication date: November 5, 2020
    Inventors: Liping LIU, Ru Bai
  • Patent number: 10772929
    Abstract: Method of use of peptides and their analogs in the treatment of acute pancreatitis are described. The disclosed peptides and analogs can significantly lower the elevated blood amylase and lipase levels caused by acute pancreatitis, reduce the degree of injury observed in pancreatic histopathology caused by pancreatitis, and significantly lower the mortality rate of acute pancreatitis.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: September 15, 2020
    Assignee: SHENZHEN HIGHTIDE BIOPHARMACEUTICAL, LTD.
    Inventors: Liping Liu, Ru Bai
  • Publication number: 20190216883
    Abstract: This invention discloses certain method of use of peptides and their analogs in the treatment of acute pancreatitis. The disclosed peptides and analogs can significantly lower the elevated blood amylase and lipase levels caused by acute pancreatitis, reduce the degree of injury observed in pancreatic histopathology caused by pancreatitis, and significantly lower the mortality rate of acute pancreatitis.
    Type: Application
    Filed: May 11, 2017
    Publication date: July 18, 2019
    Inventors: Liping LIU, Ru BAI
  • Publication number: 20190127429
    Abstract: The invention provides novel compounds, in particular peptide and peptide analogs, which exhibit functionalities useful for treating a variety of diseases and conditions, particularly diseases and conditions relating to diabetes. The compounds of the invention are also useful for treating impaired pancreatic function, treating metabolic diseases, ex vivo islet induction, expansion and proliferation for transplantation, increasing the survival of transplanted islets in vivo, promoting neuroprotection or nerve regeneration, promoting liver regeneration, and inhibiting inflammation.
    Type: Application
    Filed: March 9, 2017
    Publication date: May 2, 2019
    Inventors: Liping LIU, Ru BAI
  • Publication number: 20190023755
    Abstract: The invention provides peptides and analogs of INGAP and HIP peptides. The peptides and analogs can be used in methods for treating various diseases and conditions. Such diseases and conditions can include impaired pancreatic function, treating a metabolic disease, for example, diabetes, both type 1 and type 2 diabetes, islets induction, expansion and proliferation for transplantation, promoting neuroprotection or nerve regeneration, promoting liver regeneration or inhibiting inflammation.
    Type: Application
    Filed: May 29, 2018
    Publication date: January 24, 2019
    Inventors: Liping Liu, Ru Bai