Patents by Inventor Rubén Henriquez

Rubén Henriquez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biocompatible implant
    Patent number: 9433710
    Abstract: The present invention relates to a biocompatible implant comprising one or more metal(s), metal alloy(s), metal oxide(s) or a combination thereof, wherein a compound selected from the group consisting of an IP, an ester of an IP, and/or a pharmaceutically acceptable salt thereof, or a combination thereof, is/are covalently bound to at least a part of a metal, metal alloy or metal oxide surface of said biocompatible implant. The covalent bond between the IP and the metal, metal alloy or metal oxide surface can be further assisted by the use of a linker. An implant according to the invention provides for a modulated and/or improved osseointegrative effect when implanted into a body, such as a mammalian body, by virtue of the coating comprising covalently bound phytate.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: September 6, 2016
    Assignees: LABORATORIES SANIFIT, S. L., NUMAT BIOMEDICAL, S. L.
    Inventors: Marta Monjo Cabrer, Joan Perelló Bestard, Joana María Ramis Morey, Fernando Tur Espinosa, María del Mar Arriero Sánchez, Eva Martín Becerra, Bernat Isern Amengual, Rubén Henríquez Paláez
  • PORTABLE DEVICE FOR ANALYSING pH OR ANOTHER VARIABLE BY ELECTROCHEMICAL MEASUREMENT
    Publication number: 20160061813
    Abstract: Portable device (1) for analysing pH or another variable by electrochemical measurement comprising a sensor (2), a microprocessor (3) and display means (4) for the results of the analysis. The portable device makes it possible to carry out pre-diagnoses quickly and easily without the need for specialist staff.
    Type: Application
    Filed: September 2, 2015
    Publication date: March 3, 2016
    Inventors: Isabel GOMILA MUÑOZ, Feliciano Grases Freixedas, Antonia Costa-Bauza, Rafael M. Prieto Almirall, Eva Martin Becerra, Ruben Henriquez Pelaez, Bernat Isern Amengual, Joan Perello Bestard
  • BIOCOMPATIBLE IMPLANT
    Publication number: 20150004208
    Abstract: The present invention relates to a biocompatible implant comprising one or more metal(s), metal alloy(s), metal oxide(s) or a combination thereof, wherein a compound selected from the group consisting of an IP, an ester of an IP, and/or a pharmaceutically acceptable salt thereof, or a combination thereof, is/are covalently bound to at least a part of a metal, metal alloy or metal oxide surface of said biocompatible implant. The covalent bond between the IP and the metal, metal alloy or metal oxide surface can be further assisted by the use of a linker. An implant according to the invention provides for a modulated and/or improved osseointegrative effect when implanted into a body, such as a mammalian body, by virtue of the coating comprising covalently bound phytate.
    Type: Application
    Filed: December 26, 2012
    Publication date: January 1, 2015
    Inventors: Marta Monjo Cabrer, Joan Perelló Bestard, Joana María Ramis Morey, Fernado Tur Espinosa, María del Mar Arriero Sánchez, Eva Martín Becerra, Bernat Isern Amengual, Rubén Henríquez Paláez
  • PORTABLE DEVICE FOR ANALYSING pH OR ANOTHER VARIABLE BY ELECTROCHEMICAL MEASUREMENT
    Publication number: 20130032494
    Abstract: Portable device (1) for analysing pH or another variable by electrochemical measurement comprising a sensor (2), a microprocessor (3) and display means (4) for the results of the analysis. The portable device makes it possible to carry out pre-diagnoses quickly and easily without the need for specialist staff.
    Type: Application
    Filed: December 14, 2010
    Publication date: February 7, 2013
    Inventors: Isabel Gomila Muñoz, Feliciano Grases Freixedas, Antonia Costa-Bauza, Rafael M. Prieto Almirall, Eva Martín Becerra, Bernat Isern Amengual, Ruben Henríquez Peláez, Joan Perelló Berstard
  • Gene cluster involved in safracin biosynthesis and its uses for genetic engineering
    Patent number: 7723068
    Abstract: A gene cluster is disclosed having open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule. In addition, the present disclosure is directed to a nucleic acid sequence, suitably an isolated nucleic acid sequence, which includes or comprises at least SEQ ID NO:1, variants or portions thereof, or at least one of the sacA, sacB, sacC, sacC, sacD, sacE, sacF, sacG, sacH, sacH, saI, sacJ, orf1, orf2, orf3 or orf4 genes, including variants or portions.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: May 25, 2010
    Assignee: PharmaMar, S.A.
    Inventors: Ana Velasco Iglesias, Fernando de la Calle, Tomás Aparicio Pérez, Carmen Schleissner Sánchez, Paloma Acebo Páis, Pilar Rodríguez Ramos, Fernando Reyes Benítez, Rubén Henrìquez Peláez
  • Use of Aplidine for the Treatment of Pancreatic Cancer
    Publication number: 20100041594
    Abstract: Aplidine is active against cancer of the pancreas, including metastatic pancreatic cancer.
    Type: Application
    Filed: October 23, 2009
    Publication date: February 18, 2010
    Applicant: Pharma Mar, S.A.
    Inventors: Ramón Mangues, Rubén Henriquez, José Jimeno
  • The Gene Cluster Involved in Safracin Biosynthesis and Its Uses for Genetic Engineering
    Publication number: 20080182302
    Abstract: A gene cluster has open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule.
    Type: Application
    Filed: September 22, 2005
    Publication date: July 31, 2008
    Applicant: Pharma Mar, S.A.
    Inventors: Ana Velasco Iglesias, Fernando de la Calle, Tomás Aparicio Pérez, Carmen Schleissner Sánchez, Paloma Acebo Páis, Pilar Rodriguez Ramos, Fernando Reyes Benitez, Ruben Henriquez Pelaez
  • Sequences from an endosymbiont and their uses
    Patent number: 7309601
    Abstract: rDNA corresponding to an endosymbiotic bacteria associated with Ecteinascidia turbinata has been identified. The bacterium appears to be responsible for the biosynthesis of ecteinascidin compounds. The 16S rDNA sequence corresponding to Candidatus Endoecteinascidia frumentensis SEQ ID NO: 1 has been deposited in GeneBank with the accession number AY054370.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: December 18, 2007
    Assignee: Pharma Mar, S.A.U.
    Inventors: Beatriz Pérez Esteban, Tomás Aparicio Pèrez, Ana Velasco Iglesias, Rubén Henriquez Peláez, Rosario Muñoz Moreno, Claire Moss, Douglas McKenzie
  • Sequences from an endosymbiont and their uses
    Publication number: 20060167228
    Abstract: rDNA corresponding to an endosymbiotic bacteria associated with Ecteinascidia turbinata has been identified. The bacterium appears to be responsible for the biosynthesis of ecteinascidin compounds. The 16S rDNA sequence corresponding to Candidatus Endoecteinascidia frumentensis SEQ ID NO: 1 has been deposited in GeneBank with the accession number AY054370.
    Type: Application
    Filed: August 13, 2003
    Publication date: July 27, 2006
    Inventors: Beatriz Esteban, Tomas Aparicio Perez, Ana Velasco Iglesias, Ruben Henriquez Pelaez, Rosario Munoz Moreno
  • Gene cluster involved in safracin biosynthesis and its uses for genetic engineering
    Publication number: 20060134764
    Abstract: A gene cluster has open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule.
    Type: Application
    Filed: December 19, 2003
    Publication date: June 22, 2006
    Inventors: Ana Velasco Iglesias, Fernando De La Calle, Tomas Aparicio Perez, Carmen Schleissner Sanchez, Paloma Acebo Pais, Pilar Rodriguez Ramos, Fernando Reyes Benitez, Ruben Henriquez Pelaez
  • Use of aplidine for the treatment of pancreatic cancer
    Publication number: 20050004012
    Abstract: Aplidine is active against cancer of the pancreas, including metastatic pancreatic cancer.
    Type: Application
    Filed: October 21, 2002
    Publication date: January 6, 2005
    Inventors: Ramon Mangues, Ruben Henriquez, Jose Jimeno