Patents by Inventor Rubicon Genomics, Inc.

Rubicon Genomics, Inc. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130316913
    Abstract: The present invention concerns isolation, library preparation and selective amplification from a compositionally heterogeneous pool of DNA fragments of a fraction of molecules, such as those originating from promoter CpG islands and characterized by a high GC content. In particular, the process utilizes a heat-induced segregation of DNA molecules into GC-poor, single-stranded molecule fractions and GC-rich, double-stranded molecule fractions, with subsequent enzymatic conversion of the GC-rich, double-stranded DNA molecules into a library, and, optionally, amplification. In specific embodiments, the isolation process is used to generate promoter-enriched genomic and methylome libraries for research and diagnostic applications, for example.
    Type: Application
    Filed: February 27, 2013
    Publication date: November 28, 2013
    Applicant: Rubicon Genomics, Inc.
    Inventor: Rubicon Genomics, Inc.
  • Publication number: 20130309668
    Abstract: The present invention regards a variety of methods and compositions for obtaining epigenetic information, such as DNA methylation patterns, through the preparation, amplification and analysis of Methylome libraries.
    Type: Application
    Filed: April 9, 2013
    Publication date: November 21, 2013
    Applicant: Rubicon Genomics, Inc.
    Inventor: Rubicon Genomics, Inc.