Patents by Inventor Ruchir RASTOGI

Ruchir RASTOGI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXPRESSION OF SARS-COV PROTEINS, NUCLEIC ACID CONSTRUCTS, VIRUS LIKE PROTEINS (VLPS) AND METHODS RELEVANT THERETO
    Publication number: 20240269261
    Abstract: The present invention relates to expression of SARS-CoV like virus proteins [S, M and E] proteins; recombinant polynucleotides, polypeptides; constructs, virus-like particles (VLPs); immunogenic compositions or vaccines comprising Virus Like Particles (VLPs). Method of producing the VLPs/expressing the multi-subunit virus like proteins and method for co-expression of multi-subunit and virus like proteins (VLPs) are also provided. The present invention also provides strategies, methods, systems, kits and combinations for scalable expression, purification and enhanced production of the virus like proteins of SARS-CoV while maintaining their size range and composition. Such multi-subunit VLPs can be utilized to make immunogenic compositions or vaccines.
    Type: Application
    Filed: March 4, 2021
    Publication date: August 15, 2024
    Applicant: PREMAS BIOTECH PVT. LTD
    Inventors: Kajal ARORA, Ruchir RASTOGI, Nupur MEHROTRA, Prabuddha KUNDU
  • Recombinant expression platform, constructs and methods for expression of Difficult to Express Proteins (DTE-Ps)
    Publication number: 20230097374
    Abstract: The present invention relates to expression of SARS-CoV like virus proteins [S, M and E] proteins; recombinant polynucleotides, polypeptides; constructs, virus-like particles (VLPs); immunogenic compositions or vaccines comprising Virus Like Particles (VLPs). Method of producing the VLPs/expressing the multi-subunit virus like proteins and method for co-expression of multi-subunit and virus like proteins (VLPs) are also provided. The present invention also provides strategies, methods, systems, kits and combinations for scalable expression, purification and enhanced production of the virus like proteins of SARS-CoV while maintaining their size range and composition. Such multi-subunit VLPs can be utilized to make immunogenic compositions or vaccines.
    Type: Application
    Filed: August 1, 2022
    Publication date: March 30, 2023
    Applicant: Premas Biotech Pvt Ltd
    Inventors: Kajal Arora, Prabuddha Kumar Kundu, Ruchir Rastogi, Nupur Mehrotra Arora
  • Hemoglobin receptor as novel vaccine for leishmaniasis
    Patent number: 9764015
    Abstract: The present invention in general relates Hemoglobin receptor or its part as a novel vaccine candidate against Leishmaniasis. Specifically, the present invention envisages HbR DNA for eliciting immune response in a mammal against Leishmaniasis. Additional aspect of the present invention is related to a vaccine composition for inducing immune response against Leishmaniasis in mammals. In a preferred aspect, the present invention relates to use of HbR-polypeptide as marker for diagnosis of Leishmania in kala-azar patients.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: September 19, 2017
    Assignees: National Institute of Immunology, Indian Institute of Chemical Biology
    Inventors: Amitabha Mukhopadhyay, Syamal Roy, Deepika Gupta, Rajan Guha, Ruchir Rastogi
  • HEMOGLOBIN RECEPTOR AS NOVEL VACCINE FOR LEISHMANIASIS
    Publication number: 20150306195
    Abstract: The present invention in general relates Hemoglobin receptor or its part as a novel vaccine candidate against Leishmaniasis. Specifically, the present invention envisages HbR DNA for eliciting immune response in a mammal against Leishmaniasis. Additional aspect of the present invention is related to a vaccine composition for inducing immune response against Leishmaniasis in mammals. In a preferred aspect, the present invention relates to use of HbR-polypeptide as marker for diagnosis of Leishmania in kala-azar patients.
    Type: Application
    Filed: April 11, 2014
    Publication date: October 29, 2015
    Applicants: INDIAN INSTITUTE OF CHEMICAL BIOLOGY, NATIONAL INSTITUTE OF IMMUNOLOGY
    Inventors: Amitabha MUKHOPADHYAY, Syamal ROY, Deepika GUPTA, Rajan GUHA, Ruchir RASTOGI