Patents by Inventor Rudi Muller-Walz

Rudi Muller-Walz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110114092
    Abstract: The aim of the invention is to improve the moisture resistance of dry powder formulations for inhalation which contain a pharmaceutically ineffective carrier of not-inhalable particle size and a finely divided pharmaceutically active compound of inhalable particle size and to also improve the storage stability of said formulations. To this end, magnesium stearate is used in said formulations. On of the features of the inventive dry powder is that a high fine particle dosage or fine particle fraction can be maintained also under relatively extreme temperature and humidity conditions.
    Type: Application
    Filed: November 15, 2010
    Publication date: May 19, 2011
    Applicant: Jagotec AG
    Inventors: Manfred Keller, Rudi Müller-Walz
  • Publication number: 20070212422
    Abstract: The aim of the invention is to improve the moisture resistance of dry powder formulations for inhalation which contain a pharmaceutically ineffective carrier of not-inhalable particle size and a finely divided pharmaceutically active compound of inhalable particle size and to also improve the storage stability of said formulations. To this end, magnesium stearate is used in said formulations. On of the features of the inventive dry powder is that a high fine particle dosage or fine particle fraction can be maintained also under relatively extreme temperature and humidity conditions.
    Type: Application
    Filed: March 5, 2007
    Publication date: September 13, 2007
    Inventors: Manfred Keller, Rudi Muller-Walz
  • Patent number: 7186401
    Abstract: The aim of the invention is to improve the moisture resistance of dry powder formulations for inhalation which contain a pharmaceutically ineffective carrier of not-inhalable particle size and a finely divided pharmaceutically active compound of inhalable particle size and to also improve the storage stability of said formulations. To this end, magnesium stearate is used in said formulations. One of the features of the inventive dry powder is that a high fine particle dosage or fine particle fraction can be maintained also under relatively extreme temperature and humidity conditions.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: March 6, 2007
    Assignee: Jagotec AG
    Inventors: Manfred Keller, Rudi Müller-Walz
  • Publication number: 20040202616
    Abstract: The aim of the invention is to improve the moisture resistance of dry powder formulations for inhalation which contain a pharmaceutically ineffective carrier of not-inhalable particle size and a finely divided pharmaceutically active compound of inhalable particle size and to also improve the storage stability of said formulations. To this end, magnesium stearate is used in said formulations. One of the features of the inventive dry powder is that a high fine particle dosage or fine particle fraction can be maintained also under relatively extreme temperature and humidity conditions.
    Type: Application
    Filed: July 28, 2003
    Publication date: October 14, 2004
    Inventors: Manfred Keller, Rudi Muller-Walz
  • Publication number: 20040101483
    Abstract: Calcium salts, magnesium salts and zinc salts of palmitic acid and of stearic acid are suited for use as solid auxiliary agents for medical suspension aerosol formulations based on hydrofluoroalkanes. They improve, in particular, the suspension stability, the mechanical function of the dosing valve, the dosing precision, and the chemical stability of the active substance.
    Type: Application
    Filed: September 30, 2003
    Publication date: May 27, 2004
    Inventors: Rudi Muller-Walz, Carsten Niederlander
  • Patent number: 6645466
    Abstract: The aim of the invention is to improve the moisture resistance of dry powder formulations for inhalation which contain a pharmaceutically ineffective carrier of not-inhalable particle size and a finely divided pharmaceutically active compound of inhalable particle size and to also improve the storage stability of said formulations. To this end, magnesium stearate is used in said formulations. One of the features of the inventive dry powder is that a high fine particle dosage or fine particle fraction can be maintained also under relatively extreme temperature and humidity conditions.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: November 11, 2003
    Assignee: Jago Research AG
    Inventors: Manfred Keller, Rudi Müller-Walz
  • Patent number: 6585958
    Abstract: A pressure-liquefied propellant mixture for aerosols, comprising dinitrogen monoxide and a hydrofluoroalkane having 1 to 3 carbon atoms, in particular 1,1,1,2-tetrafluoroethane and/or 1,1,1,2,3,3,3-heptafluoropropane, makes possible an improvement in the wetting properties of pharmaceutically active compounds, whereby the formulation problems existing with hydrofluoroalkanes can be overcome with respect to suspension and solution aerosols and thus improved medicinal aerosol formulations can be obtained. With the aid of dinitrogen monoxide, it is also possible to influence the pressure and thus the particle size distribution specifically and, by displacement of oxygen from the hydrofluoroalkanes, to improve the storage stability of oxidation-sensitive active compounds. If desired, the propellant mixture can additionally contain carbon dioxide.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: July 1, 2003
    Assignee: Jago Research AG
    Inventors: Manfred Keller, Kurt Herzog, Rudi Müller-Walz, Holger Kraus
  • Patent number: 6475467
    Abstract: The use of solid, pharmaceutically acceptable salts of cromoglycic acid and/or nedocromil as carriers in a therapeutically and prophylactically inefficacious amount in suspension aerosol formulations of pharmaceutical active compounds improves the dispersion properties, increases the chemical and physical stability of moisture-sensitive active compounds, makes possible a more accurate dosage, in particular even of low-dose active compounds, and as a rule permits the abandonment of surface-active agents.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: November 5, 2002
    Assignee: Jago Research AG
    Inventors: Manfred Keller, Kurt Herzog, Rudi Müller-Walz, Holger Kraus