Patents by Inventor Rudolf Hendrikus Jozef DAS

Rudolf Hendrikus Jozef DAS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioreactor system and single-use cell culture container for use therein
    Patent number: 10836986
    Abstract: A bioreactor system (1A; 1B) includes a variable volume container (3) having a flexible outer wall (27, 29) defining a cell-culture chamber for containing a fluid culture medium, and anchorage dependent cells in suspension. A agitator unit of the system (1A; 1B) is in fluid communication with first, second and third fluid ports (43, 45, 47A; 47B) for performing controlled replenishment of the culture medium in the cell-culture chamber, to admit fresh nutritive culture medium into the cell-culture chamber and for allowing draining of waste culture medium from the cell-culture chamber. The agitator unit further has a roller (15) for pinching the outer wall of the variable volume container (3) to thereby increase its a volume that forms the cell-culture chamber, starting from the initial minimum volume area (23), and means for gently agitating the cell-culture chamber.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: November 17, 2020
    Assignee: SCINUS CELL EXPANSION B.V.
    Inventors: Emerentius Gerardus Roosloot, Rudolf Hendrikus Jozef Das, Joost Dick De Bruijn, Pieter Theo Elias Van Santen
  • BIOREACTOR SYSTEM AND SINGLE-USE CELL CULTURE CONTAINER FOR USE THEREIN
    Publication number: 20160152935
    Abstract: A bioreactor system (1A; 1B) includes a variable volume container (3) having a flexible outer wall (27, 29) defining a cell-culture chamber for containing a fluid culture medium, and anchorage dependent cells in suspension. A agitator unit of the system (1A; 1B) is in fluid communication with first, second and third fluid ports (43, 45, 47A; 47B) for performing controlled replenishment of the culture medium in the cell-culture chamber, to admit fresh nutritive culture medium into the cell-culture chamber and for allowing draining of waste culture medium from the cell-culture chamber. The agitator unit further has a roller (15) for pinching the outer wall of the variable volume container (3) to thereby increase its a volume that forms the cell-culture chamber, starting from the initial minimum volume area (23), and means for gently agitating the cell-culture chamber.
    Type: Application
    Filed: July 18, 2014
    Publication date: June 2, 2016
    Applicant: XPAND BIOTECHNOLOGY B.V.
    Inventors: Emerentius Gerardus ROOSLOOT, Rudolf Hendrikus Jozef DAS, Joost Dick DE BRUIJN, Pieter Theo Elias VAN SANTEN