Patents by Inventor Rudolf Hulspas

Rudolf Hulspas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200072731
    Abstract: A flow cell for particle processing such as particle sorting, may be operatively engaged to a particle processing apparatus. The fluid contact surfaces of the flow cell may be fully enclosed. Further, the flow cell may encapsulate all fluid contact surfaces in the particle processing apparatus. The enclosing or encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The flow cell may employ any suitable technique for processing particles. The flow cell may be disposable and suitable for use in droplet sorting. The flow cell may include an operatively sealed sort chamber having a particle stream focusing region, an orifice, an interrogation zone and a sorting region.
    Type: Application
    Filed: August 7, 2019
    Publication date: March 5, 2020
    Inventors: Johnathan Charles Sharpe, Rudolf Hulspas, Kristopher Scott Buchanan
  • Patent number: 10379029
    Abstract: A flow cell for particle processing such as particle sorting, may be operatively engaged to a particle processing apparatus. The fluid contact surfaces of the flow cell may be fully enclosed. Further, the flow cell may encapsulate all fluid contact surfaces in the particle processing apparatus. The enclosing or encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The flow cell may employ any suitable technique for processing particles. The flow cell may be disposable and suitable for use in droplet sorting. The flow cell may include an operatively sealed sort chamber having a particle stream focusing region, an orifice, an interrogation zone and a sorting region.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: August 13, 2019
    Assignee: CYTONOME/ST, LLC
    Inventors: Johnathan Charles Sharpe, Rudolf Hulspas, Kristopher Scott Buchanan
  • Patent number: 10274414
    Abstract: Systems, methods and non-transitory storage medium are disclosed herein for adjusting an output of a particle inspection system representative of a particle characteristic for a particle flowing in a flow-path of a particle processing system. More particularly, the output may be processed and a calibrated output of the particle characteristic generated. In other embodiments, one or more calibration particles are used. Thus, an output of a particle inspection system representative of a particle characteristic for one or more calibration particles flowing in a flow-path of a particle processing system may be compared relative to a standard and an action may be taken based on a result of the comparing the output to the standard.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: April 30, 2019
    Assignee: CYTONOME/ST, LLC
    Inventors: Johnathan Charles Sharpe, Emanuel Tito Mendes Machado, Rudolf Hulspas
  • Patent number: 10197493
    Abstract: A microfluidic multiple channel particle analysis system which allows particles from a plurality of particle sources to be independently simultaneously entrained in a corresponding plurality of fluid streams for analysis and sorting into particle subpopulations based upon one or more particle characteristics.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: February 5, 2019
    Assignee: CYTONOME/ST, LLC
    Inventors: Johnathan Charles Sharpe, Emanuel Tito Mendes Machado, Blair D. Morad, Rudolf Hulspas, Donald Francis Perrault, Jr.
  • Publication number: 20170343467
    Abstract: A microfluidic multiple channel particle analysis system which allows particles from a plurality of particle sources to be independently simultaneously entrained in a corresponding plurality of fluid streams for analysis and sorting into particle subpopulations based upon one or more particle characteristics.
    Type: Application
    Filed: April 10, 2017
    Publication date: November 30, 2017
    Inventors: Johnathan Charles Sharpe, Emanuel Tito Mendes Machado, Blair D. Morad, Rudolf Hulspas, Donald Francis Perrault, JR.
  • Patent number: 9618442
    Abstract: A microfluidic multiple channel particle analysis system which allows particles from a plurality of particle sources to be independently simultaneously entrained in a corresponding plurality of fluid streams for analysis and sorting into particle subpopulations based upon one or more particle characteristics.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: April 11, 2017
    Assignee: CYTONOME/ST, LLC
    Inventors: Johnathan Charles Sharpe, Emanuel Tito Mendes Machado, Blair D. Morad, Rudolf Hulspas, Donald Francis Perrault, Jr.
  • Publication number: 20150276576
    Abstract: A microfluidic multiple channel particle analysis system which allows particles from a plurality of particle sources to be independently simultaneously entrained in a corresponding plurality of fluid streams for analysis and sorting into particle subpopulations based upon one or more particle characteristics.
    Type: Application
    Filed: June 15, 2015
    Publication date: October 1, 2015
    Inventors: Johnathan Charles Sharpe, Emanuel Tito Mendes Machado, Blair D. Morad, Rudolf Hulspas, Donald Francis Perrault, JR.
  • Patent number: 9057676
    Abstract: A microfluidic multiple channel particle analysis system (1) which allows particles (2) from a plurality of particle sources (3) to be independently simultaneously entrained in a corresponding plurality of fluid streams (4) for analysis and sorting into particle subpopulations (5) based upon one or more particle characteristics (6).
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: June 16, 2015
    Assignee: CYTONOME/ST, LLC
    Inventors: Johnathan Charles Sharpe, Emanuel Tito Mendes Machado, Blair Morad, Rudolf Hulspas, Donald Francis Perrault, Jr.
  • Publication number: 20140343869
    Abstract: Systems, methods and non-transitory storage medium are disclosed herein for adjusting an output of a particle inspection system representative of a particle characteristic for a particle flowing in a flow-path of a particle processing system. More particularly, the output may be processed and a calibrated output of the particle characteristic generated. In other embodiments, one or more calibration particles are used. Thus, an output of a particle inspection system representative of a particle characteristic for one or more calibration particles flowing in a flow-path of a particle processing system may be compared relative to a standard and an action may be taken based on a result of the comparing the output to the standard.
    Type: Application
    Filed: May 19, 2014
    Publication date: November 20, 2014
    Applicant: CYTONOME/ST, LLC
    Inventors: Johnathan Charles Sharpe, Emanuel Tito Mendes Machado, Rudolf Hulspas
  • Publication number: 20140170697
    Abstract: A flow cell for particle processing such as particle sorting, may be operatively engaged to a particle processing apparatus. The fluid contact surfaces of the flow cell may be fully enclosed. Further, the flow cell may encapsulate all fluid contact surfaces in the particle processing apparatus. The enclosing or encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The flow cell may employ any suitable technique for processing particles. The flow cell may be disposable and suitable for use in droplet sorting. The flow cell may include an operatively sealed sort chamber having a particle stream focusing region, an orifice, an interrogation zone and a sorting region.
    Type: Application
    Filed: September 18, 2013
    Publication date: June 19, 2014
    Applicant: CYTONOME/ST, LLC
    Inventors: Johnathan Charles Sharpe, Rudolf Hulspas, Kristopher Scott Buchanan
  • Patent number: 8731860
    Abstract: Systems, methods and non-transitory storage medium are disclosed herein for adjusting an output of a particle inspection system representative of a particle characteristic for a particle flowing in a flow-path of a particle processing system. More particularly, the output may be processed and a calibrated output of the particle characteristic generated. In other embodiments, one or more calibration particles are used. Thus, an output of a particle inspection system representative of a particle characteristic for one or more calibration particles flowing in a flow-path of a particle processing system may be compared relative to a standard and an action may be taken based on a result of the comparing the output to the standard.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: May 20, 2014
    Assignee: Cytonome/ST, LLC
    Inventors: Johnathan Charles, Emanuel Tito Mendes Machado, Rudolf Hulspas
  • Publication number: 20120307244
    Abstract: A microfluidic multiple channel particle analysis system (1) which allows particles (2) from a plurality of particle sources (3) to be independently simultaneously entrained in a corresponding plurality of fluid streams (4) for analysis and sorting into particle subpopulations (5) based upon one or more particle characteristics (6).
    Type: Application
    Filed: February 4, 2011
    Publication date: December 6, 2012
    Applicant: Cytonome/ST, LLC
    Inventors: Johnathan Charles Sharpe, Emanuel Tito Mendes Machado, Blair Morad, Rudolf Hulspas, Donald Francis Perrault, JR.
  • Publication number: 20110196637
    Abstract: Systems, methods and non-transitory storage medium are disclosed herein for adjusting an output of a particle inspection system representative of a particle characteristic for a particle flowing in a flow-path of a particle processing system. More particularly, the output may be processed and a calibrated output of the particle characteristic generated. In other embodiments, one or more calibration particles are used. Thus, an output of a particle inspection system representative of a particle characteristic for one or more calibration particles flowing in a flow-path of a particle processing system may be compared relative to a standard and an action may be taken based on a result of the comparing the output to the standard.
    Type: Application
    Filed: February 7, 2011
    Publication date: August 11, 2011
    Applicant: CYTONOME/ST, LLC
    Inventors: Johnathan C. Sharpe, Emanuel Tito Mendes Machado, Rudolf Hulspas