Patents by Inventor Rudolf Jaenisch

Rudolf Jaenisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing non-human mammals
    Publication number: 20040231014
    Abstract: A method of producing mutant/targeted non-human mammals, such as mutant mice that does not require production of chimera and permits the introduction of multiple mutations in embryos and, thus, avoids the necessity of breeding to combine all of the desired mutations in a single animal. The method is efficient in producing ES mice.
    Type: Application
    Filed: February 26, 2004
    Publication date: November 18, 2004
    Applicant: Whitehead Institute For Biomedical Research
    Inventors: Kevin C. Eggan, Rudolf Jaenisch
  • Method of producing mutant mice
    Patent number: 6784336
    Abstract: A method of producing mutant/targeted non-human mammals, such as mutant mice that does not require production of chimera and permits the introduction of multiple mutations in embryos and, thus, avoids the necessity of breeding to combine all of the desired mutations in a single animal. The method is efficient in producing ES mice.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: August 31, 2004
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Kevin C. Eggan, Rudolf Jaenisch
  • Generation of non-human mammals by nuclear cloning
    Publication number: 20040040051
    Abstract: A method of producing a non-human mammalian embryo, such as a mouse embryo, by nuclear cloning, in which the nucleus from a non-human mammalian embryonic stem (ES) cell (e.g., a non-human mammalian F1 ES cell), such as the nucleus of a mouse F1 ES cell, is introduced into an enucleated non-human mammalian oocyte, such as an enucleated mouse oocyte; embryos produced by the method; a method of producing mice from the resulting embryos and the mice produced thereby.
    Type: Application
    Filed: April 29, 2003
    Publication date: February 26, 2004
    Applicants: Whitehead Institute for Biomedical Research, The University of Hawaii
    Inventors: William M. Rideout, Teruhiko Wakayama, Kevin C. Eggan, Ryuzo Yanagimachi, Hidenori Akutsu, Rudolf Jaenisch
  • Correction of genetic defects
    Publication number: 20030228293
    Abstract: A method of correcting of treating a genetic disorder by combining therapeutic cloning and gene therapy.
    Type: Application
    Filed: March 7, 2003
    Publication date: December 11, 2003
    Applicants: Whitehead Institute for Biomedical Research, The General Hospital Corporation
    Inventors: William Rideout, Konrad Hochedlinger, Michael Kyba, Rita Perlingeiro, George Q. Daley, Rudolf Jaenisch
  • Inbred embryonic stem-cell derived mice
    Publication number: 20030204862
    Abstract: An improved and reproducible method for the generation of ES mice from inbred ES cells, without the need to generate a chimeric mouse intermediate is provided. The inbred ES cells may be recombinant or genetically modified, resulting in ES mice that are transgenic. The method may also be used for the fast production of ES mice strains homozygous for a defined genetic alteration.
    Type: Application
    Filed: March 4, 2003
    Publication date: October 30, 2003
    Inventors: Ralf Kuehn, Anja Rode, Rudolf Jaenisch, Branko Zevnik
  • Method of producing non-human mammals
    Publication number: 20020078470
    Abstract: A method of producing mutant/targeted non-human mammals, such as mutant mice that does not require production of chimera and permits the introduction of multiple mutations in embryos and, thus, avoids the necessity of breeding to combine all of the desired mutations in a single animal. The method is efficient in producing ES mice.
    Type: Application
    Filed: September 20, 2001
    Publication date: June 20, 2002
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Kevin C. Eggan, Rudolf Jaenisch
  • Method of producing non-human mammals
    Publication number: 20020062493
    Abstract: A method of producing mutant/targeted non-human mammals, such as mutant mice that does not require production of chimera and permits the introduction of multiple mutations in embryos and, thus, avoids the necessity of breeding to combine all of the desired mutations in a single animal. The method is efficient in producing ES mice.
    Type: Application
    Filed: January 5, 2001
    Publication date: May 23, 2002
    Applicant: Whitehead Institute for Biomedical Research Nine Cambridge Center, Cambridge, MA 02142
    Inventors: Kevin C. Eggan, Rudolf Jaenisch