Abstract: Described is a high voltage, high current operational amplifier in which galvanic separation of the input and output stages is achieved by means of an optical bridge, consisting of an LED and a photoresistor or phototransistor. The output stage utilizes two current sources, connected with inverse polarity and controlled by the optical bridge, thus allowing the transition between the low-voltage input stage and the high voltage output stage in a single step. Depending on the exact embodiment of the amplifier this invention can be customized to function with the properties of a Class A, B or C operational amplifier and can, in each of these embodiments, be used as an isolation amplifier.