Patents by Inventor Rudolf L. Then

Rudolf L. Then has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-bacterial cephalosporin compounds
    Patent number: 5147871
    Abstract: There are presented anti-bacterial cephalosporins having broad antimicrobial activity of the formula ##STR1## wherein R.sub.1 is an antibiotically active quinolonyl; R.sub.2 is selected from the group consisting of hydrogen, lower alkoxy, amino, lower alkylthio and amido; R.sub.3 is selected from the group consisting of hydrogen, and acyl group, and m is 0, 1 or 2 and the readily hydrolysable esters or salts of these compounds and hydrates of the compounds of formula I or of their esters or salts.
    Type: Grant
    Filed: December 5, 1991
    Date of Patent: September 15, 1992
    Assignee: Hoffmann La-Roche, Inc.
    Inventors: Harry A. Albrecht, Ka-Kong Chan, Dennis D. Keith, Rudolf L. Then, Manfred Weigele