Abstract: The present invention relates to attention bias modification treatment. In order to improve the treatment effect, an ABM system is proposed with a neural brain response monitoring device, such as functional magnetic resonance imaging (fMRI), magnetoencephalography (MEG), and/or electroencephalography (EEG), to provide real-time information regarding neural brain responses in order to personalize and optimize the ABM treatment.

Abstract: Disclosed herein is a medical system (200, 300) comprising an augmented reality system (204) configured for rendering virtual objects within a visual three-dimensional field of view of an operator (214).

Abstract: A system provides quality control in medical imaging Noise sources are evaluated which can adversely affect the image quality. The noise sources which are evaluated comprise at least two of a device noise source, an operator noise source and a subject (the patient being imaged) noise source, all creating sources of noise during the acquisition of the medical image. A quality control indicator is determined and output to the operator based on the evaluated noise sources.

Abstract: The invention provides a method of medical imaging. The method comprises: receiving, for a current active time window (204A-N) and during a brain activity analysis session (200, 500), fMRI data of a region of interest (309) of a subject (318) in an active state. A transverse relaxation, T2*, map may be generated from the fMRI data using a predefined model of fMRI data variations. The generated T2* map may be compared with a reference T2* map. A blood-oxygen-level dependent (BOLD) response of the region of interest (309) during the current active time window (204 A-N) may be estimated using the results of the comparison.

Abstract: The present invention relates to an apparatus for task determination during brain activity analysis. The apparatus comprises an input unit (20), a processing unit (30), and an output unit (40). The input unit is configured to provide the processing unit with measurement data of the brain of a patient performing a task during brain activity analysis. The processing unit is configured to determine a measure of brain activity based on the measurement data of the brain.

Abstract: The present invention relates to a system (10) for functional magnetic resonance image data acquisition. The system comprises an input unit (20), a magnetic resonance imaging “MRI” device (30), an electroencephalography “EEG” data acquisition device (40), and a processing unit (50). The input unit is configured to provide task based information to a patient, wherein the task based information extends over a period of time. The MRI device is configured to acquire functional magnetic resonance imaging “fMRI” data relating to brain activity of the patient, wherein the fMRI data extends over the period of time. The EEG device is configured to acquire EEG data relating to electrical activity of the brain of the patient, wherein the EEG data extends over the period of time. The processing unit is configured to utilize the task based information that extends over the period of time and the EEG data that extends over the period of time to determine at least one first sub-set period of time over the period of time.

Abstract: The present disclosure relates to a medical imaging method, comprising: receiving (201) a set of subject parameters descriptive of a subject; in response to inputting (203) the set of subject parameters into a trained deep neural network, DNN, receiving (205) from the trained DNN a predicted task; presenting the task to the subject; controlling (207) an MRI system (700) for acquiring fMRI data from the subject in response to the predicted task performed by the subject during the acquisition

Abstract: The invention provides a method of medical imaging. The method comprises: receiving, for a current active time window (204A-N) and during a brain activity analysis session (200, 500), fMRI data of a region of interest (309) of a subject (318) in an active state. A transverse relaxation, T2*, map may be generated from the fMRI data using a predefined model of fMRI data variations. The generated T2* map may be compared with a reference T2* map. A blood-oxygen-level dependent (BOLD) response of the region of interest (309) during the current active time window (204 A-N) may be estimated using the results of the comparison.

Abstract: A magnetic resonance imaging protocol includes an acquisition segment to control an acquisition sequence to acquire magnetic resonance signals at a lower main magnetic field strength. A reconstruction segment controls reconstruction of a diagnostic magnetic resonance image from the magnetic resonance signals at a lower main magnetic field strength. A segmentation segment controls segmentation of a predetermined image detail of the diagnostic magnetic resonance image. In the magnetic resonance imaging protocol, the acquisition sequence has a set of imaging parameters that cause the image quality of the diagnostic magnetic resonance to be similar to the image quality of the magnetic resonance training images, e.g., acquired at 7 T.

Abstract: A magnetic resonance imaging protocol includes an acquisition segment to control an acquisition sequence to acquire magnetic resonance signals at a lower main magnetic field strength. A reconstruction segment controls reconstruction of a diagnostic magnetic resonance image from the magnetic resonance signals at a lower main magnetic field strength. A segmentation segment to control segmentation of a pre-determined image-detail of the diagnostic magnetic resonance image. In the magnetic resonance imaging protocol: the acquisition sequence has a set of imaging parameters that cause the image quality of the diagnostic magnetic resonance to be similar to the image quality of the magnetic resonance training images.

Abstract: A device for magnetic resonance imaging of a body placed in an examination volume is configured to generate a series of MR spin echo signals from a first nuclear spin species by subjecting at least a portion of the body to an MR imaging pulse sequence. The MR imaging pulse sequence includes a spatially non-selective excitation RF pulse, a plurality of refocusing RF pulses, and a plurality of phase encoding switched magnetic field gradients. The device is further is configured to acquire the MR spin echo signals without application of frequency encoding magnetic field gradients; and to reconstruct an MR image from the acquired MR spin echo signals.

Abstract: A method for MRI imaging to obtain information about a local physiochemical parameter after administration to a patient of a contrast agent including at least one non-responsive contrast enhancing entity that does not occur naturally in a human body and at least one responsive contrast enhancing entity attached to or mixed with the non-responsive contrast enhancing entity. By using such non-responsive contrast enhancing entities, a value for the physicochemical parameter can be obtained by acquiring only three images, providing a method which will be easier to apply in a clinical routine, since it will be faster and less sensitive to motion or flow artifacts.

Abstract: The present invention provides a method MRI imaging. By applying a time modulation to the contrast enhancement of an MRI contrast agent, the method according to the invention leads to images with improved signal-to-noise ratio in the contrast-enhanced areas, strongly suppressed unwanted signal in the unenhanced areas, and reduced artefacts, such as motion artefacts.

Abstract: The present invention relates to a method for the production of scaffold materials and/or scaffolds for tissue and/or organ engineering, said method comprising the addition of at least one anchoring unit for a labelling agent, to at least one scaffold material and/or to at least one scaffold.

Abstract: A method of using a fluorinated polymer having a glass transition temperature below 40 C as a contrast agent in 19F magnetic resonance imaging (MRI) of a solid object, said solid object comprising said contrast agent. The invention relates to a solid object comprising a structural component and an imaging component, wherein the imaging component is at least one fluorinated polymer. The invention relates to a method for 19F MRI in solid state using a contrast agent comprising a fluorinated polymer as well as a method for in vivo visualizing a scaffold. It further relates to a method for in vivo monitoring the degradation of a solid object in time, wherein the degradation is monitored in time by using 19F MRI to visualize the solid object, and wherein the amount of degradation of the solid object is determined based on the decrease in the visibility of the amount of 19F.

Abstract: Described is the use of perfluoro-t-butyl cyclohexane in a contrast agent for molecular imaging, notably F MRI. Particularly, the perfluoro-t-butyl cyclohexane is present in the form of an aqueous emulsion of nanoparticles comprising the perfluoro compound as a core, and an emulsifying agent, such as a phospholipid, as a shell. The shell can be functionalized with other moieties that play a role in imaging, notably ligands for targeted binding and/or contrast agents or labels with a view to other imaging modalities. The latter particularly refers to 1H MRI contrast agents as well as radiolabels for SPECT.

Abstract: The invention relates to a method of MR imaging of at least a portion of a body of a patient placed in an examination volume of an MR device. The object of the invention is to improve CEST contrast enhanced imaging. The method of the invention comprises the following steps: a) saturation of nuclear magnetization of exchangeable protons of a CEST contrast agent administered to the patient by subjecting the portion of the body to at least one frequency-selective saturation RF pulse matched to the MR frequency of exchangeable protons of the CEST contrast agent, wherein the saturation period, i.e.

Abstract: The invention relates to a method for acquiring MR images (200-216) of an object, said object comprising at least first and second kinds of nuclei, the method comprising: acquiring (300; 304) first MR image data (200; 202; 204) of the object, wherein the first nuclei are excited, acquiring (302) second MR image data (206-216) of the object, wherein the second nuclei are excited, analyzing the first MR image data (200; 202; 204) determining motion parameters describing a motion of the object based on said analysis, motion correcting the first and/or second MR image data (206-216) using said motion parameters.

Abstract: Magnetic resonance monitoring of a target (30) uses the detected magnetic resonance to determine movement such as diffusion of contrast agent relative to the object, and uses the movement to discriminate (50, 60) a part of the contrast agent which is bound to the target, from the rest of the contrast agent. The need for clearing agents can be avoided or reduced, and hence imaging is instantaneous. A “stationary spin map” of the object can be formed by comparing the movements in the different directions, and determining if the differences between them are less than a given threshold. Determining isotropic movement in this way for a number of locations on the object allows the map to be generated.

Abstract: The invention relates to a device for magnetic resonance imaging of a body (7) placed in an examination volume. The device (1) is arranged to a) generate a series of MR spin echo signals from a first nuclear spin species by subjecting at least a portion of the body (7) to an MR imaging pulse sequence comprising a spatially non-selective excitation RF pulse, a plurality of refocusing RF pulses, and a plurality of phase encoding switched magnetic field gradients; b) acquire the MR spin echo signals without application of frequency encoding magnetic field gradients; c) reconstruct an MR image from the acquired MR spin echo signals.