Patents by Inventor Rudolf Mueller

Rudolf Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10369100
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: August 6, 2019
    Assignee: Dr. Falk Pharma GmbH
    Inventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
  • Publication number: 20180026948
    Abstract: A system and method for encrypting and decrypting data for communication via a communication device, in which at least certain aspects of the encryption and decryption functions are performed on a chip and using physical signal conductors rather than in software. The chip includes a chip controller for managing the other components, an encryption/decryption module for performing the encryption and decryption functions, a memory element for containing the encryption and decryption keys, and an I/O control module for controlling input and output operations. These components are connected by the physical signal conductors which facilitate communication therebetween under the control of a protocol provided by the chip controller. The chip may also include an RF spectrum analyser for analysing signals to determine whether electronic eavesdropping is occurring, in which case the user is warned if eavesdropping is detected.
    Type: Application
    Filed: July 22, 2016
    Publication date: January 25, 2018
    Inventors: Vladimir Lazecky, Rudolf Müller, Jan Müller
  • Patent number: 9492440
    Abstract: This invention relates to bicyclic amide compounds, pharmaceutical compositions and methods for use in the prevention and treatment of a variety of conditions and/or disease states including cerebral insufficiency, through the enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors as defined herein. These brain networks, which are involved in regulation of breathing, and cognitive abilities related to memory impairment, such as is observed in a variety of dementias, in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia, respiratory depression, sleep apneas, attention deficit hyperactivity disorder and affective or mood disorders, and in other disorders wherein a deficiency in neurotrophic factors is implicated, as well as other disorders as described herein.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: November 15, 2016
    Assignee: RESPIRERX PHARMACEUTICALS INC
    Inventors: Rudolf Mueller, Leslie Street
  • Patent number: 8642633
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: February 4, 2014
    Assignee: Cortex Pharmaceuticals, Inc.
    Inventors: Leslie Street, Rudolf Mueller, Steven Lee
  • Patent number: 8507482
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors. These brain networks, which are involved in cognitive abilities related to memory impairment, such as is observed in a variety of dementias, in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia, sleep apneas, attention deficit hyperactivity disorder and affective or mood disorders, and in disorders wherein a deficiency in neurotrophic factors is implicated, as well as conditions such as stroke-induced central sleep apnea, obstructive sleep apnea, congenital hypoventilation syndrome, among others.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: August 13, 2013
    Assignee: Cortex Pharmaceuticals, Inc.
    Inventors: Rudolf Mueller, Leslie J. Street
  • Publication number: 20130190351
    Abstract: This invention relates to bicyclic amide compounds, pharmaceutical compositions and methods for use in the prevention and treatment of a variety of conditions and/or disease states including cerebral insufficiency, through the enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors as defined herein. These brain networks, which are involved in regulation of breathing, and cognitive abilities related to memory impairment, such as is observed in a variety of dementias, in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia, respiratory depression, sleep apneas, attention deficit hyperactivity disorder and affective or mood disorders, and in other disorders wherein a deficiency in neurotrophic factors is implicated, as well as other disorders as described herein.
    Type: Application
    Filed: July 25, 2012
    Publication date: July 25, 2013
    Applicant: CORTEX PHARMACEUTICALS, INC.
    Inventors: Rudolf Mueller, Leslie Street
  • Patent number: 8404682
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: March 26, 2013
    Assignee: Cortex Pharmaceuticals, Inc.
    Inventors: Leslie Street, Rudolf Mueller, Steven Lee
  • Patent number: 8263591
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: September 11, 2012
    Assignee: Cortex Pharmaceuticals, Inc.
    Inventors: Rudolf Mueller, Leslie Street
  • Publication number: 20120122861
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors. These brain networks, which are involved in cognitive abilities related to memory impairment, such as is observed in a variety of dementias, in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia, sleep apneas, attention deficit hyperactivity disorder and affective or mood disorders, and in disorders wherein a deficiency in neurotrophic factors is implicated, as well as conditions such as stroke-induced central sleep apnea, obstructive sleep apnea, congenital hypoventilation syndrome, among others.
    Type: Application
    Filed: January 11, 2012
    Publication date: May 17, 2012
    Applicant: CORTEX PHARMACEUTICALS, INC.
    Inventors: Rudolf MUELLER, Leslie J. STREET
  • Patent number: 8173644
    Abstract: This invention relates to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed in a variety of dementias, an in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to a compound useful for treatment of such conditions, and methods of using this compound for such treatment.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: May 8, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Alexis Cordi, Gary Rogers, Rudolf Mueller
  • Patent number: 8168632
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of disorders of respiration such as overdose of an alcohol, an opiate, an opioid, a barbiturate, an anesthetic, or a nerve toxin. In a particular aspect, the invention relates to bicyclic amide compounds useful for treatment of such conditions, and methods of using these compounds for such treatment.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: May 1, 2012
    Assignee: Cortex Pharmaceuticals, Inc.
    Inventors: Rudolf Mueller, Leslie J. Street
  • Patent number: 8119632
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: February 21, 2012
    Assignee: Cortex Pharmaceuticals, Inc.
    Inventors: Rudolf Mueller, Leslie J. Street
  • Publication number: 20120035173
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors. These brain networks, which are involved in regulation of breathing, and cognitive abilities related to memory impairment, such as is observed in a variety of dementias, in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia, respiratory depression, sleep apneas, attention deficit hyperactivity disorder and affective or mood disorders, among numerous others. In a particular aspect, the invention relates to compounds useful for treatment of such conditions, and methods of using these compounds for such treatment.
    Type: Application
    Filed: September 6, 2011
    Publication date: February 9, 2012
    Inventors: Leslie Street, Rudolf Mueller, Steven Lee
  • Patent number: 8110584
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: February 7, 2012
    Assignee: Cotex Pharmaceuticals, Inc.
    Inventors: Rudolf Mueller, Leslie Street
  • Patent number: 8013003
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: September 6, 2011
    Assignee: Cortex Pharmaceuticals, Inc.
    Inventors: Leslie Street, Rudolf Mueller, Steven Lee
  • Publication number: 20110003835
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Application
    Filed: September 3, 2010
    Publication date: January 6, 2011
    Applicant: CORTEX PHARMACEUTICALS, INC.
    Inventors: Rudolf Mueller, Leslie Street
  • Publication number: 20100303579
    Abstract: A first and second component joint includes using a fastener having a first end, and a flange having a diameter greater than a tubular barrel portion. A second end having a second tubular barrel portion merges into a shoulder of a flange part having a greater diameter than the barrel portion. The first tubular barrel portion is deformed radially outwardly sandwiching the first component between the flange and the first barrel portion. The second end of the fastener is introduced through a hole in the second component by applying the second component to the first component so the shoulder of the flanged part abuts the second component spacing the second component from the first component. The fastener device is fastened to the second component by deforming the second tubular barrel portion radially outwardly sandwiching the second component between the shoulder and the tubular barrel portion.
    Type: Application
    Filed: June 1, 2010
    Publication date: December 2, 2010
    Applicant: PROFIL Verbindungstechnik GmbH & Co., KG
    Inventors: Rudolf Müller, Michael Vieth, Hans Broich
  • Publication number: 20100286177
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Application
    Filed: August 8, 2008
    Publication date: November 11, 2010
    Applicant: CORTEX PHARMACEUTICALS, INC.
    Inventors: Rudolf Mueller, Leslie Street
  • Publication number: 20100267728
    Abstract: This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for basic and higher order behaviors.
    Type: Application
    Filed: September 19, 2008
    Publication date: October 21, 2010
    Applicant: CORTEX PHARMACEUTICALS, INC.
    Inventors: Rudolf Mueller, Leslie J. Street, Stanislaw Rachwal, Kashinatham Alisala
  • Patent number: 7799913
    Abstract: This invention related to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed In a variety of dementias, and in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson?s disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to compounds useful for treatment of such conditions and methods of using these compounds for such treatment.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: September 21, 2010
    Assignee: Cortex Pharmaceuticals, Inc.
    Inventors: Gary A. Rogers, Matthew Allan, Clayton Harris, Jianjie Huang, Christopher M. Marrs, Rudolf Mueller, Stanislaw Rachwal