Patents by Inventor Rudolf Mulder
Rudolf Mulder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060041271Abstract: A covered vascular filter can be placed in a blood vessel, for the purpose of intercepting thrombus. The filter may be introduced to a desired site for medical treatment through a catheter which defines a lumen or passage and a distal port or opening. The filter tends to resiliently expand from a compressed shape when it is inside the catheter lumen, to an expanded shape when the filter is pushed from the catheter lumen. A cover or sleeve over those portions of the filter that would otherwise contact the vessel wall tends to reduce pressure on the vessel wall. The sleeve also tends to resist growth of the vessel wall among the elements of the filter, called endothelialization. In other words, the sleeve resists incorporation of the filter elements into the vessel wall, enabling the filter to be retrievable for a longer time. The various features of the present invention may be used singly or in any combination, as desired in a particular vascular filter.Type: ApplicationFiled: August 20, 2004Publication date: February 23, 2006Inventors: Gjalt Bosma, Yvonne Hoogeveen, Michiel Koom, Rudolf Mulder
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Publication number: 20050080449Abstract: The present invention relates to a safety cartridge for a medical filter which can be inserted through a percutaneous access point, via a catheter or introducer, and placed in a blood vessel or other body passage. Filters may have features which are not longitudinally symmetrical, such as anchors or barbs which angle toward one end, or a retrieval hook at only one end. Depending on the physician's selection of the access point, the filter may be introduced to a desired site for treatment from opposing directions. However, it is desirable to introduce the filter with the desired alignment (inserting the desired end in first) regardless of where the selected access point is, and accordingly regardless of which direction of approach to the desired site. As a result, it is desirable to provide a safety cartridge. Cartridges hold filters in an initial compressed shape during storage and insertion into the patient.Type: ApplicationFiled: September 30, 2004Publication date: April 14, 2005Inventor: Rudolf Mulder
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Patent number: 5342958Abstract: Compounds of the formula ##STR1## wherein A is a hydrogen atoms, a halogen atom, a methyl group, or a methoxy group;B is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group, with the proviso that A and B ar not both a hydrogen atom;X and Y each are an oxygen atom or a sulfur atom;R is a hydrogen atom, an alkyl group, a hydroxy group, an alkoxy group, an alkoxymethyl group, an acyl group, or an alkoxycarbonyl group;R.sub.1 is a hydrogen atom, an alkyl group, a halogen substituted alkyl group, an alkoxy substituted alkyl group, an alkylthio substituted alkyl group, a cyano substituted alkyl group, a 1-cycloalkenyl group, a benzyl group, a halogen substituted benzyl group, a hydroxy group, an alkoxy group, an acyl group, an alkoxycarbonyl group, an alkoxythiocarbonyl group, an alkylsulfonyl group, or a phenylsulfonyl group, while furthermore R and R.sub.1 together with the group ##STR2## indicated in the above formula may form a ring system; and R.sub.Type: GrantFiled: August 11, 1993Date of Patent: August 30, 1994Assignee: Solvay Duphar International Research B.V.Inventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 5245071Abstract: Compounds of the formula ##STR1## wherein A is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group;B is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group, with the proviso that A and B ar not both a hydrogen atom;X and Y each are an oxygen atom or a sulfur atom;R is a hydrogen atom, an alkyl group, a hydroxy group, an alkoxy group, an alkoxymethyl group, an acyl group, or an alkoxycarbonyl group;R.sub.1 is a hydrogen atom, an alkyl group, a halogen substituted alkyl group, an alkoxy substituted alkyl group, an alkylthio substituted alkyl group, a cyano substituted alkyl group, a 1-cycloalkenyl group, a benzyl group, a halogen substituted benzyl group, a hydroxy group, an alkoxy group, an acyl group, an alkoxycarbonyl group, an alkoxythiocarbonyl group, an alkylsulfonyl group, or a phenylsulfonyl group, while furthermore R and R.sub.1 together with the group ##STR2## indicated in the above formula may form a ring system; and R.sub.Type: GrantFiled: June 3, 1992Date of Patent: September 14, 1993Assignee: Duphar International Research B.V.Inventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 5142064Abstract: Compounds of the formula ##STR1## wherein A is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group;B is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group, with the proviso that A and B ar not both a hydrogen atom;X and Y each are an oxygen atom or a sulfur atom;R is a hydrogen atom, an alkyl group, a hydroxy group, an alkoxy group, an alkoxymethyl group, an acyl group, or an alkoxycarbonyl group;R.sub.1 is a hydrogen atom, an alkyl group, a halogen substituted alkyl group, an alkoxy substituted alkyl group, an alkylthio substituted alkyl group, a cyano substituted alkyl group, a 1-cycloalkenyl group, a benzyl group, a halogen substituted benzyl group, a hydroxy group, an alkoxy group, an acyl group, an alkoxycarbonyl group, an alkoxythiocarbonyl group, an alkylsulfonyl group, or a phenylsulfonyl group, while furthermore R and R.sub.1 together with the group ##STR2## indicated in the above formula may form a ring system; and R.sub.Type: GrantFiled: July 7, 1986Date of Patent: August 25, 1992Assignee: Duphar International Research B.V.Inventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 4833151Abstract: Certain organic compounds derived from urea or thio-urea having insectical activity and methods of their preparation are disclosed. The compounds according to the invention have been found to interfere with the mechanism of metamorphoses which occurs in insects. Hence, the substances according to the invention are specifically active against insects. Owing to this specificity and because of the absence of phytotoxicity effects, the compounds of this invention are of prime importance.Type: GrantFiled: May 28, 1986Date of Patent: May 23, 1989Assignee: Duphar International Research B.V.Inventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 4607044Abstract: Certain organic compounds derived from urea or thiourea having insectical activity and methods of their preparation are disclosed. The compounds according to the invention have been found to interfere with the mechanism of metamorphoses which occurs in insects. Hence the substances according to the invention are specifically active against insects. Owing to this specificity and because of the absence of phytotoxicity effects, the compounds of this invention are of prime importance.Type: GrantFiled: October 30, 1984Date of Patent: August 19, 1986Assignee: Duphar International Research B.V.Inventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 4174393Abstract: The invention relates to novel 1,3,4-substituted-.DELTA..sup.2 -pyrazolines having an insecticidal activity. The compounds are particularly active against larvae of insects for example larvae of Colorado beetle, cabbage white butterfly and yellow-fever mosquito. On the basis of their activity, the compounds, after having been processed to the usual composition, may be used in controlling insects, particularly in the field of agriculture and horticulture. The dosage is 0.05 -1 kg of the active substance per hectare.Type: GrantFiled: January 5, 1977Date of Patent: November 13, 1979Assignee: Duphar International Research B.V.Inventors: Jan J. Van Daalen, Rudolf Mulder
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Patent number: 4166124Abstract: New 2,6-dihalobenzoyl urea derivatives and their use as insecticides.Type: GrantFiled: August 25, 1976Date of Patent: August 28, 1979Assignee: U.S. Philips CorporationInventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 4156007Abstract: The invention relates to new 1,3,4-substituted .DELTA..sup.2 -pyrazolines having an insecticidal activity. The compounds are active in particular against larvae of insects such as larvae of colorado beetle, cabbage butterfly and yellow-fever mosquito. On the basis of their activity the compounds, after having been processed to the usual compositions, may be used in controlling insects, in particular in the field of agriculture and horticulture. The dosage is 0.05-1 kg of the active substance per hectare. A most active compound is the substance 1-(4-chlorophenylcarbamoyl)-3-(4-chlorophenyl)-4-phenyl-.DELTA..sup.2 -pyrazoline.Type: GrantFiled: September 26, 1977Date of Patent: May 22, 1979Assignee: U.S. Philips CorporationInventors: Jan J. van Daalen, Rudolf Mulder
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Patent number: 4110469Abstract: Benzoyl phenyl urea or thiourea derivatives are used as active substances in insecticidal compositions.Type: GrantFiled: December 29, 1976Date of Patent: August 29, 1978Assignee: U.S. Philips CorporationInventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 4095026Abstract: It has been found that novel pyrazoline compounds have a strong and specific biocidal activity against arthropods and especially insects. In addition to their more direct biocidal activity the novel compounds influence the pattern of motion of arthropods, which results in uncoordinated movements. A highly active substance is, for example, 1-(4-chlorophenylcarbamoyl)-3-(4-chlorophenyl)-5-(4-isopropoxyphenyl)-.DEL TA..sup.2 -pyrazoline. After the substances have been worked up into preparations they can be used for controlling arthropods and especially insects which are pests in agriculture and horticulture and in industrial products.Type: GrantFiled: August 19, 1976Date of Patent: June 13, 1978Assignee: U.S. Philips CorporationInventors: Rudolf Mulder, Kobus Wellinga
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Patent number: 4070365Abstract: The invention relates to new 1,3,4-substituted .DELTA..sup.2 -pyrazolines having an insecticidal activity. The compounds are active in particular against larvae of insects such as larvae of colorado beetle, cabbage butterfly and yellow-fever mosquito. On the basis of their activity the compounds, after having been processed to the usual compositions, may be used in controlling insects, in particular in the field of agriculture and horticulture. The dosage is 0.05-1 kg of the active substance per hectare. A most active compound is the substance 1-(4-chlorophenylcarbamoyl)-3-(4-chlorophenyl)-4-phenyl.DELTA..sup.2 -pyrazoline.Type: GrantFiled: July 9, 1975Date of Patent: January 24, 1978Assignee: U.S. Philips CorporationInventors: Jan Johannes van Daalen, Rudolf Mulder
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Patent number: 4013717Abstract: New organic compounds derived from urea or thiourea, insecticidal preparations on the basis of the new substances and methods of producing the substances.Type: GrantFiled: October 23, 1975Date of Patent: March 22, 1977Assignee: U.S. Philips CorporationInventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 4010271Abstract: It has been found that novel pyrazoline compounds have a strong and specific biocidal activity against arthropods and especially insects. In addition to their more direct biocidal activity the novel compounds influence the pattern of motion of arthropods, which results in uncoordinated movements. A highly active substance is, for example, 1-(4-chlorophenylcarbamoyl)-3-(4-chlorophenyl)-5-(4-isopropoxyphenyl)-.DEL TA..sup.2 -pyrazoline. After the substances have been worked up into preparations they can be used for controlling arthropods and especially insects which are pests in agriculture and horticulture and in industrial products.Type: GrantFiled: May 30, 1975Date of Patent: March 1, 1977Assignee: U.S. Philips CorporationInventors: Rudolf Mulder, Kobus Wellinga
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Patent number: 3991073Abstract: It has been found that novel pyrazoline compounds have a strong and specific biocidal activity against arthropods and especially insects. In addition to their more direct biocidal activity the novel compounds influence the pattern of motion of arthropods, which results in uncoordinated movements. A highly active substance is, for example, 1-(4-chlorophenylcarbamoyl)-3-(4-chlorophenyl)-5-(4-isopropoxyphenyl)-.DEL TA..sup.2 -pyrazoline. After the substances have been worked up into preparations they can be used for controlling arthropods and especially insects which are pests in agriculture and horticulture and in industrial products.Type: GrantFiled: February 7, 1975Date of Patent: November 9, 1976Assignee: U.S. Philips CorporationInventors: Rudolf Mulder, Kobus Wellinga
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Patent number: 3989842Abstract: Organic compounds derived from urea or thiourea are used as active ingredients in insecticidal compositions.Type: GrantFiled: November 8, 1974Date of Patent: November 2, 1976Assignee: U.S. Philips CorporationInventors: Kobus Wellinga, Rudolf Mulder
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Patent number: 3933908Abstract: New organic compounds derived from urea or thiourea, insecticidal preparations on the basis of the new substances and methods of producing the substances.Type: GrantFiled: April 25, 1973Date of Patent: January 20, 1976Assignee: U.S. Philips CorporationInventors: Kobus Wellinga, Rudolf Mulder