Abstract: A method of forming a dental restoration for a tooth having an outer surface includes acquiring a first three-dimensional representation representative of the outer surface of the tooth; generating a design of a first part of the dental restoration based on the first three-dimensional representation of the tooth; forming the first part of the dental restoration; preparing the tooth to form a prepared tooth while forming the first part of the dental restoration; obtaining a second three-dimensional representation of the prepared tooth; generating a design of a second part of the dental restoration based on at least the second three-dimensional representation of the prepared tooth; merging the design of the second part of the dental restoration to the first part of the dental restoration; and forming the second part of the dental restoration.

Abstract: The invention relates to a polypeptide having the sequence Z1-Gln-Ala-Lys-Ile-Lys-Gln-Ile-Ile-Asn-Met-Trp-Gln-Z2. The polypeptide is used for retroviral transfection/transduction.

Abstract: Polypeptide having the sequence

Abstract: An N-terminally protected peptide having the sequence (SEQ?ID?NO:?1) X-Glu-Cys-Lys-Ile-Lys-Gln-Ile-Ile-Asn-Met-Trp-Gln, wherein X is a group protecting the N-terminal of the peptide.

Abstract: An N-terminally protected peptide having the sequence (SEQ ID NO: 1) X-Glu-Cys-Lys-Ile-Lys-Gln-Ile-Ile-Asn-Met-Trp-Gln, wherein X is a group protecting the N-terminal of the peptide.

Abstract: The present invention relates to the field of biotechnology. It involves the decomposition and conversion of organic educts, in particular biomass feedstock, lignin, guaiacol; p-coumaryl alcohol; coniferyl alcohol; sinapyl alcohol; cresol; phenol; catechol; polysaccharides; cellulose hemicellulose; xylose; glucose; fructose; proteins; amino acids; triacylglycerides and/or fatty acids into useful organic compounds with the help of biocatalysts. A method of producing an organic product comprises i) fluid-assisted decomposition of an organic educt under sub- or supercritical conditions ii) obtaining an intermediate product from step i) iii) subjecting the intermediate product to biocatalytic conversion, by contacting the intermediate product obtained in step ii) with a biocatalyst, wherein said biocatalyst is a host cell selected from the group consisting of bacteria, yeast, filamentous fungi, cyanobacteria, algae, and plant cells.

Abstract: A composition containing at least two of the following active substances A, B, C, wherein: A=at least one hormone stimulating the production of cAMP; B=at least one substance inhibiting the degradation of a cyclic nucleotide; C=at least one hormone stimulating the production of cGMP.

Abstract: A composition containing at least two of the following active substances A, B, C, wherein: A=at least one hormone stimulating the production of cAMP; B=at least one substance inhibiting the degradation of a cyclic nucleotide; C=at least one hormone stimulating the production of cGMP.

Abstract: The invention discloses the human chemokine HCC-1, N-terminally truncated HCC-1 molecules and glycosylated HCC-1 which improve the homing of stem cells into the -bone marrow during stem cell transplantation. It is also provided a procedure for producing the polypeptides by recombinant techniques or chemical synthesis and for producing antibodies against such polypeptide. Furthermore, it is disclosed the modification of the polypeptide by coupling of amino acid residues and/or chemical groups or deleting amino-acids generating potent derivatives of the polypeptide. Another aspect of the invention provides a combination of the polypeptide of the present invention and a suitable pharmaceutical carrier for providing a therapeutically effective amount of the polypeptide for the treatment of various associated diseases.

Abstract: A medicament comprising at least one agonist of receptors selected from the group consisting of the CCR3, CCR6 or CCR8 receptor or combinations thereof and a pharmaceutically acceptable carrier.

Abstract: The invention relates to the polypeptide COM and its derivatives, and methods for its preparation and recovery in a pure or partially purified form from body fluids and tissues, and its use as a medicament.

Abstract: A composition containing at least two of the following active substances A, B, C, wherein: A=at least one hormone stimulating the production of cAMP; B=at least one substance inhibiting the degradation of a cyclic nucleotide; C=at least one hormone stimulating the production of cGMP.

Abstract: The electrode of tungsten material has a cylindrical shaft and a conical tip, in which the conical tip is made essentially by radial deformation, such as hammering or cross-rolling, of the tip portion (9) of the electrode blank (5). This changes the grain structure to be converging. A flat top or plateau (10) can be ground at the very end of the tip.

Abstract: A control device for a variable displacement hydrostatic machine having a stroke-volume regulator which is responsive to an actuating pressure. The control device includes a booster pump. The delivery pressure of the machine is the actuating pressure unless the delivery pressure of the machine is insufficient in which case the actuating pressure is a feed pressure produced by the booster pump. The control device includes a plurality of delivery-pressure lines and a proportioning pressure regulator having an outlet pressure which is proportionally reduced relative to the intake pressure connected between each delivery-pressure line and the stroke-volume regulator.

Abstract: A power control device for an adjustable hydrostatic pump with a lever controlling a control valve piston and a pressure measuring piston loaded with feed pressure acting on said lever to control the pressure feed to a servo piston is provided wherein the pressure measuring piston loaded with feed pressure is mounted in a structural member slidable with the servo piston and slides lengthwise of the lever and the control valve piston is biased by resilient member toward the pressure measuring piston.

Abstract: A valve is provided, particularly as a part of a block control device, made up of an elongate housing having a longitudinal bore with spaced work chambers, inlet chambers and exhaust chambers intersecting the bore and an elongate cylindrical spool slidable in said bore, having a second bore in each end of said spool, a brake piston movable in each second bore, a pair of restrictor passage means one in said spool and one in said brake piston connecting the interior of said spool with both ends of each bore in the spool on opposite ends of the piston, a pair of spaced transverse passages at each end of the spool communicating with each bore in the spool and spaced to connect a work chamber and pressure fluid chamber at one end of the spool and a work chamber and exhaust chamber at the other end of the spool in a work position, an annular groove in the brake piston capable of connecting said spaced passages within the bore in the spool whereby in said work position pressure fluid flows from a pressure fluid cham

Abstract: The invention relates to a process for separating solids from liquid matter by means of gravity, using a three-dimensional filter element and an alluvial filter layer wherein a gas is fed into the medium to be treated prior to its introduction into the filter element in the form of fine or finest bubbles which accumulate on the solid particles. The particles loaded with air floated up rapidly to the upper level of the column of liquid in the filter element, forming a layer of sludge. Said layer built up continuously an alluvial filter layer at the internal surface of the water-permeable supporting filter element from the bottom upwards along the wall relative to the rising level of the liquid in the filter element. The process, realized in the presence or absence of flocculating agents, results in a higher separation degree with regard to the solids content as well as an increased elimination of the biological oxygen demand.