Patents by Inventor Rudolf Schmid

Rudolf Schmid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4853472
    Abstract: A process for producing natural vitamin E and intermediates in this process.
    Type: Grant
    Filed: September 9, 1988
    Date of Patent: August 1, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: David L. Coffen, Rudolf Schmid, Mark J. Sebastian
  • Patent number: 4827004
    Abstract: Novel Isoprene Derivatives which have mucosa-protective and gastric acid secretion-inhibiting properties and are useful for combatting ulcers both by treating and as a prophylaxis against gastric and/or duodenal ulcers.
    Type: Grant
    Filed: August 24, 1987
    Date of Patent: May 2, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Albert Fischli, Max Schmid, Rudolf Schmid
  • Patent number: 4789750
    Abstract: 6-Etherified hydroxy -2-(4',8',12'-trimethyl-5'-tridecenyl)-2,5,7,8-tetramethylchromans with an oxo or hydroxy substituent at the 2' position which may be substituted with an arylsulfonyl or a carboxyalkyl at the 3' position and containing a single or double bond at the 11 position, said chromans being intermediates for producing natural vitamin E.
    Type: Grant
    Filed: March 27, 1987
    Date of Patent: December 6, 1988
    Assignee: Hoffman-La Roche Inc.
    Inventors: David L. Coffen, Rudolf Schmid, Mark J. Sebastian
  • Patent number: 4754032
    Abstract: Compounds of formula I ##STR1## can be used as optical brighteners.
    Type: Grant
    Filed: February 26, 1986
    Date of Patent: June 28, 1988
    Assignee: Sandoz Ltd.
    Inventors: David L. Connell, John M. Farrar, Jurg Heller, Hans-Rudolf Schmid
  • Patent number: 4717502
    Abstract: Aqueous optical brightener compositions consisting essentially of:(a) at least one optical brightener of formula ##STR1## in which R.sub.1 is hydrogen or --SO.sub.3 M;R.sub.2 is hydrogen or --SO.sub.3 M;R.sub.3 is hydrogen, C.sub.2-3 -hydroxyalkyl, C.sub.1-4 -alkyl, --CH.sub.2 --CH.sub.2 --CN or --CH.sub.2 --CH.sub.2 --CONH.sub.2 ;R.sub.4 is hydrogen, C.sub.1-4 -alkyl, C.sub.2-3 -hydroxyalkyl, hydroxy-ethoxy-ethyl, N,N-Bis-(C.sub.1-3 -alkyl)-amino-C.sub.2-6 -alkyl or benzyl;orR.sub.3 and R.sub.4 together with the neighboring nitrogen atom signify a morpholine, pyrrolidine, piperidine or N-methylpiperazine ring;andM is hydrogen or a colorless cation; provided that at most one of R.sub.3 and R.sub.
    Type: Grant
    Filed: January 21, 1986
    Date of Patent: January 5, 1988
    Assignee: Sandoz Ltd.
    Inventor: Hans-Rudolf Schmid
  • Patent number: 4649546
    Abstract: A gas laser, includes:a tube having two ends to be filled with gas; anda plate-shaped window hermetically sealing at least one of the ends of the tube;the window including a carrier plate and a layer coating the inside of the carrier plate;the tube being formed of a first material with a first thermal coefficient of expansion (H.sub.1) at least in vicinity of the one end thereof having the window;the layer being formed of a second material with a second thermal coefficient of expansion (H.sub.2);the carrier plate being formed of a third material with a third thermal coefficient of expansion (H.sub.3);the first and second materials being unadapted to each other; andthe third material being thermally matched to the first material.
    Type: Grant
    Filed: February 6, 1984
    Date of Patent: March 10, 1987
    Assignee: Siemens Aktiengesellschaft
    Inventor: Rudolf Schmid
  • Patent number: 4578462
    Abstract: The manufacture of optically active bifunctional compounds of the general formula ##STR1## wherein R represents protected hydroxymethyl, protected formyl or alkoxycarbonyl and R.sup.1 represents a group of the formula ##STR2## or --CH.sub.2 --CH.dbd.NR.sup.2 in which R.sup.2 and R.sup.3 represent lower alkyl or cycloalkyl or R.sup.2 and R.sup.3 together with the nitrogen atom represent a heterocyclic ring,by isomerizing compounds of the general formula ##STR3## wherein R, R.sup.2 and R.sup.3 have the above significance and R.sup.3 can additionally signify hydrogen,is described.The compounds of formula I are potential intermediates in the manufacture of, inter alia, natural vitamin E and natural vitamin K.sub.1.
    Type: Grant
    Filed: August 22, 1983
    Date of Patent: March 25, 1986
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hans-Jurgen Hansen, Rudolf Schmid, Max Schmid
  • Patent number: 4556740
    Abstract: Novel chiral phosphorus compounds of the general formula ##STR1## wherein R signifies substituted or unsubstituted phenyl, R.sup.1 and R.sup.2, which can be the same or different, signify hydrogen, lower alkyl, lower alkoxy, di-lower alkylamino or protected hydroxymethyl or R.sup.1 and R.sup.2 together signify the group ##STR2## in which m represents a number 3 to 5, R.sup.4 represents lower alkyl, substituted or unsubstituted phenyl or benzyl and R.sup.5 represents lower alkyl or both R.sup.5 's together represent lower alkylene, R.sup.3 signifies methyl, lower alkoxy, di-lower alkylamino or fluorine and n signifies the number 0, 1, 2 or 3, are described.The compounds of formula I are useful in the form of complexes with a metal of Group VIII as catalysts for asymmetric hydrogenations and enantioselective hydrogen displacements in prochiral allylic systems.
    Type: Grant
    Filed: August 19, 1983
    Date of Patent: December 3, 1985
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hans-Jurgen Hansen, Rudolf Schmid
  • Patent number: 4553240
    Abstract: In a coaxially constructed gas laser with a capillary fused at one end to the glass casing surrounding it and enclosed at its free end by a supporting spring the supporting spring contains a perforated disc of a material adapted thermally to the jacket glass and is framed by a shrunk-on jacket constriction. Such a mount is extraordinarily stable mechanically and thermally. In a preferred embodiment the supporting spring is a multipart spring: attached to the thermally adapted perforated disc are two other, smaller perforated discs consisting of a spring material of temperature constancy and containing the actual spring elements.
    Type: Grant
    Filed: August 13, 1984
    Date of Patent: November 12, 1985
    Assignee: Siemens Aktiengesellschaft
    Inventor: Rudolf Schmid
  • Patent number: 4300899
    Abstract: The present invention relates to compounds of formula I.sub.x, ##STR1## in which Y.sub.1 is (C.sub.1-6) alkoxy, Z is hydrogen, alkali metal or ammonium, andn is 1 or 2and a process for treating anionic dyeable substrates therewith to reserve the same against anionic dyes.
    Type: Grant
    Filed: February 20, 1980
    Date of Patent: November 17, 1981
    Assignee: Sandoz Ltd.
    Inventor: Hans-Rudolf Schmid
  • Patent number: 4025507
    Abstract: Disclosed are compounds of formula I, ##STR1## in which THE R.sub.1 's are the same and signify hydrogen or methyl,The R.sub.2 's are the same and signify hydrogen; C.sub.1-6 alkyl; cyclohexyl, unsubstituted or substituted by up to three C.sub.1-6 alkyl radicals; or benzyl, unsubstituted or substituted by up to two substituents selected from halogen, C.sub.1-6 alkoxy and C.sub.1-6 alkyl, andThe M's signify hydrogen or a nonchromophoric cation,Their production and use as optical brightening agents for cellulosic substrates, particularly paper substrates.
    Type: Grant
    Filed: June 25, 1974
    Date of Patent: May 24, 1977
    Assignee: Sandoz Ltd.
    Inventors: Fritz Fleck, Hans-Rudolf Schmid
  • Patent number: 3970647
    Abstract: Disclosed are stilbene compounds of formula I, ##SPC1##in whichR.sub.1 signifies hydrogen, halogen or C.sub.1-6 alkyl,R.sub.2 signifies hydrogen or methyl,R.sub.3 signifies cyano or a radical --CONR.sub.7 R.sub.8 in which either R.sub.7 and R.sub.8, independently, each signifies hydrogen, C.sub.1-6 alkyl or C.sub.2-6 hydroxyalkyl, or R.sub.7 and R.sub.8, together with the nitrogen atom, signify a pyrrolidine, piperidine or morpholine radical,Either R.sub.4 and R.sub.5, independently, each signifiesC.sub.1-6 alkyl or C.sub. 2-6 hydroxyalkyl, or R.sub.4 and R.sub.5, together with the nitrogen atom, form a radical (a) ##EQU1## in which --X-- signifies --CH.sub.2 --, --O--, --S--, a direct bond, or --NR.sub.9 --, in which R.sub.9 signifies C.sub. 1-6 alkyl or C.sub.2-6 hydroxy-alkyl,R.sub.6 signifies hydrogen or C.sub.1-6 alkyl, unsubstituted or substituted by hydroxy, cyano or aminocarbonyl,M signifies hydrogen or a non-chromophoric cation,A.sup.
    Type: Grant
    Filed: February 11, 1974
    Date of Patent: July 20, 1976
    Assignee: Sandoz Ltd.
    Inventors: Hans Balzer, Fritz Fleck, Hans-Rudolf Schmid
  • Patent number: 3941778
    Abstract: New stilbene derivatives of formula: ##SPC1##In whichR.sub.1 signifies a hydrogen or halogen atom, or a lower alkyl group;R.sub.2 signifies a hydrogen atom; a cycloalkyl group which is unsubstituted or substituted by one or more lower alkyl groups; or a lower alkyl group which is unsubstituted or substituted by a hydroxyl, lower alkoxy or hydroxysubstituted lower alkoxy group or by a radical of formula (a); ##SPC2##M signifies a hydrogen atom or an equivalent of a colourless cation;n signifies 1 or 2; Alkylene signifies C.sub.1.sub.-8 alkylene;And the rings A and B are unsubstituted or substituted by one or more substituents selected from halogen atoms and lower alkyl, lower alkoxy, cyano and SO.sub.3 M groups;The compound containing at least six SO.sub.3 M groups per molecule, are useful as optical brighteners. They are produced by successive condensation of each of the three amino-containing moieties around the triazine nucleus, as an amine, with a cyanuro halide.
    Type: Grant
    Filed: February 15, 1974
    Date of Patent: March 2, 1976
    Assignee: Sandoz Ltd., (Sandoz AG)
    Inventors: Curt Mueller, Hans-Rudolf Schmid