Abstract: The present invention features solid compositions comprising amorphous Compound I. For instance, Compound I may be formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.

Abstract: The present invention features solid compositions comprising Compound IA, IB or IC, or a pharmaceutically acceptable salt thereof, in an amorphous form. In one embodiment, Compound IA, IB or IC, or a pharmaceutically acceptable salt thereof, is formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.

Abstract: The present invention features solid compositions comprising amorphous Compound I. For instance, Compound I may be formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.

Abstract: The present invention features solid compositions comprising Compound IA, IB or IC, or a pharmaceutically acceptable salt thereof, in an amorphous form. In one embodiment, Compound IA, IB or IC, or a pharmaceutically acceptable salt thereof, is formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.

Abstract: The present invention features solid compositions comprising amorphous Compound I. For instance, Compound I may be formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.

Abstract: A process for producing a liquid formulation of salts of sulfonated azo dyes by coupling an at least equimolar amount of diazotized aminoarylsulfonic acids I H2N—Ar—SO3H??(I), where Ar is phenylene (which may be monosubstituted by sulfo) or naphthylene (which may be mono- or disubstituted by sulfo and/or monosubstituted by hydroxyl) onto the coupling product of an unsubstituted or methyl-substituted phenylenediamine with itself comprises dissolving the azo dye in a basic medium and then subjecting the solution to a nanofiltration.

Abstract: The present invention features processes of making tablets having reduced internal fractures. In one aspect, the processes comprise the steps of (1) compressing a pre-tabletting material in a die to form a tablet, where an internal surface of the die is lubricated with at least one lubricant and the pre-tabletting material comprises at least one therapeutic agent and at least one pharmaceutically acceptable polymer; and (2) ejecting said tablet from said die. In another aspect, the processes employ a granular or powdery pre-tabletting material which comprises at least one therapeutic agent and at least one pharmaceutically acceptable polymer, wherein 90% of the particles in the pre-tabletting material are smaller than 400 ?m.

Abstract: A solid dispersion product comprising at least one N-aryl urea-based pharmaceutically active agent or an agent of related structural type is obtained by a) preparing a liquid mixture containing the at least one active agent, at least one pharmaceutically acceptable matrix-forming agent, at least one pharmaceutically acceptable surfactant and at least one solvent, and b) removing the solvent(s) from the liquid mixture to obtain the solid dispersion product.

Abstract: Substituted and unsubstituted flavone or isoflavone glycoside derivatives of the formula [A1-C(?O)O]m—[X—O-Z]—[O—C(?O)-A2]n, wherein [X—O-Z] represents a flavone or isoflavone glycoside structure, particularly a naringin residue, X is a flavone or isoflavone corresponding to formula (IIa) or formula (IIb): wherein the flavone or isoflavone residue is substituted one or more times and/or reduced one or more times; Z represents a mono-, di- or polysaccharide, which is acetally-bound at the benzopyran group to X and ester-substituted by —O—C(?O)-A2; [A1-C(?O)] is an acyl group on the flavone or isoflavone; A1 and A2 independently, represent a polyunsaturated C15-26 alkenyl group containing at least four isolated and/or at least two conjugated double bonds, or an arylaliphatic radical with 1-to-4 methylene groups between the ester group and the aromatic ring; [C(?O)A2] is an acyl group; n is an integer other than 0; m is an integer, including 0; and R1, R2 and R are hydroxyl groups or hydrogen atoms.

Abstract: Compositions, in particular, for the treatment of the hair or of the skin, comprising at least one compound which is selected from L-carnitine or L-carnitine derivatives and at least one further substance which is selected from the group formed from active ingredients obtainable from the plants of the genus Echinacea, and also taurine and derivatives thereof.

Abstract: The present invention relates to aqueous liquid formulations comprising 5-25% by weight of a dye composition comprising 70-95% by weight of a dye obtainable by reduction or thermal treatment of Direct Yellow 11 1-30% by weight of a blue direct dye and 0-20% by weight of a red direct dye (all based on the dye composition) 1-15% by weight of a saturated, cyclic or acyclic water-soluble amine comprising a primary, secondary or tertiary amino group and at least one further functional group selected from primary, secondary and tertiary amino groups, OH groups and ether groups, and 1-30% by weight of urea based on the total weight of the aqueous liquid formulation, wherein the total amount of water-soluble amine and urea does not exceed 40% by weight, and also their use for dyeing cellulose material especially paper.

Abstract: The present invention relates to an aqueous liquid formulation comprising ?5–25% by weight of a dye composition comprising 20–100% by weight of Direct Yellow 11 or of a dye obtainable by reduction or thermal treatment of Direct Yellow 11 ?0–30% by weight of a blue direct dye, ?0–30% by weight of a red direct dye, and ?0–60% by weight of a brown direct dye all based on the dye composition, and ?1–25% by weight of poly-N-vinylformamide and/or of a polymer obtained by polymerization of a mixture of one or more ethylenically unsaturated monomers and >50% by weight of N-vinylformamide based on total monomers, based on the total weight of the aqueous liquid formulation.

Abstract: The invention relates to flavone and isoflavone glycoside derivatives of general formula (I): [A1-C(═O)O]m—[X—O-Z]-[O—C(═O)-A2]n (I), wherein [X—O-Z] represents a flavone or isoflavone glycoside structure, wherein X represents a flavone or isoflavone parent substance of formula (IIa) or (IIb), said (iso)flavone parent substance being mono- or multisubstituted and/or mono- or multireduced (hydrogenated), wherein Z (sugar) represents a mono-, di- or polysaccharide which is acetally bonded to the radical X and is ester-substituted with A2 n-times, [A1-C(═O)] representing an acyl radical on the flavone or isoflavone parent substance, wherein A1 and A2, independently of each other, represent a polyunsaturated C15-C25-alkenyl radical with at least 4 isolated and/or at least 2 conjugated double bonds or an arylaliphatic radical with 1-4 methylene groups between the ester group and the aromatic ring, wherein [C(═O)A2&rs

Abstract: Benzimidazoles of the formula ##STR1## where n and q independently of one another are each 1 or 2, R.sup.1 is hydrogen, chlorine or methyl, R.sup.2 is hydrogen, unsubstituted or substituted C.sub.1 -C.sub.4 -alkyl, halogen, nitro or C.sub.1 -C.sub.4 -alkanoyl, L is C.sub.2 -C.sub.6 -alkylene and An.sup.$ is one equivalent of an anion, are used as charge stabilizers in electrostatic toners.

Abstract: Benzimidazoles of the formula ##STR1## where n and q are each 1 or 2, the radicals R are each hydrogen, chlorine or methyl,L is a bridge member and An.sup..crclbar. is one equivalent of an anion, are used as charge stabilizers in electrostatic toners.

Abstract: Electrostatic toners contain a polymeric binder and, as a charge stabilizer, a compound of the formula ##STR1## where Z is C.sub.1 -C.sub.20 -alkyl which is unsubstituted or substituted by phenyl or Z is C.sub.5 -C.sub.7 -cycloalkyl or unsubstituted or substituted phenyl, X and Y are each cyano or a radical of the formula --CO--OR.sup.1, --CO--NR.sup.1 R.sup.2 or --C--R.sup.3, where R.sup.2 is C.sub.1 -C.sub.20 -alkyl which is unsubstituted or substituted by phenyl or R.sup.1 is C.sub.5 -C.sub.7 -cycloalkyl, R.sup.2 is hydrogen or C.sub.1 -C.sub.4 -alkyl and R.sup.3 is C.sub.1 -C.sub.20 -alkyl which is unsubstituted or substituted by phenyl or R.sup.3 is C.sub.5 -C.sub.7 -cycloalkyl or unsubstituted or substituted phenyl, or X and Y together form a radical of the formula --CO--L--CO-- or --CO--CH.dbd.C(CH.sub.3)--O--CO--, where L is C.sub.2 -C.sub.4 -alkylene, and cat.sup..sym. is one equivalent of a cation.

Abstract: Disazo dyes suitable for preparing inks have the formula ##STR1## where m is 1 or 2,n is 0 or 1,Z.sup.1 is hydrogen or substituted or unsubstituted C.sub.1 -C.sub.4 -alkyl,Z.sup.2 is hydrogen, substituted or unsubstituted C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkanoyl, substituted or unsubstituted benzoyl, C.sub.1 -C.sub.4 -alkylsulfonyl, substituted or unsubstituted phenylsulfonyl or a derivatized 1,3,5-triazinyl radical, andD is the radical of a diazo component of the class of the thiazole, thiophene, aminobenzoic acid or phenylenediamine compounds.

Abstract: Triphenylmethane dyes of the formula ##STR1## where each R.sup.1 is independently of the others hydrogen or substituted or unsubstituted C.sub.1 -C.sub.6 -alkyl, or two R.sup.1 radicals together with the nitrogen atom joining them form a heterocyclic radical,R.sup.2 and R.sup.5 is independently of the others hydrogen or C.sub.1 -C.sub.4 -alkyl,R.sup.3 and R.sup.4 is independently of the others hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,An.sup..crclbar. is one equivalent of an anion, andn is 1 or 2,preparable from piperazine derivatives as intermediates, are useful for coloring paper.