Abstract: A device for establishing geometric values at least from a first region (MB1) and from a second region (MB3), distanced from the first region (MB1), of a transparent or diffusive object, comprises a coherence tomograph with an object arm, a reference arm, a detector arm, and a light source (ALQ) for emitting light. The device has a first path, formed by the object arm and/or the reference arm, having a first optical path length and a second path having a second optical path length, along which the light emitted by the light source (ALQ) can propagate.

Abstract: A Michelson-interferometer which has two reference arms and a short coherence length is used for the method and apparatus for measurement of geometric values on transparent or diffuse objects (19). The basic optical delay times of the reference arms (11, 12) are chosen in such a manner that they result in an optical delay time difference corresponding to a layer thickness, as a geometric value. The at least two reference arm beams (33a, 35a) are passed to a single rotating path-length variation element (23), with a mutual spatial offset angle (dw). A delay-time change, which is dependent on the rotation angle, of the reference arm beams is produced as a function of a rotation angle caused by rotation, in order to allow a delay-time change caused by the path-length variation element (23) to be applied successively to the basic optical delay times in the reference arms (11, 12).

Abstract: A Michelson-interferometer which has two reference arms and a short coherence length is used for the method and apparatus for measurement of geometric values on transparent or diffuse objects (19). The basic optical delay times of the reference arms (11, 12) are chosen in such a manner that they result in an optical delay time difference corresponding to a layer thickness, as a geometric value. The at least two reference arm beams (33a, 35a) are passed to a single rotating path-length variation element (23), with a mutual spatial offset angle (dw). A delay-time change, which is dependent on the rotation angle, of the reference arm beams is produced as a function of a rotation angle caused by rotation, in order to allow a delay-time change caused by the path-length variation element (23) to be applied successively to the basic optical delay times in the reference arms (11, 12).

Abstract: The invention relates to an ophtalmological examination and/or treatment station that comprises, in the form of modules, a lighting device, an observation device, an optical measuring system, an evaluation unit and a patient module which is positioned immediately in front of the patient's eye. The patient module can be optically linked with the locally remote lighting device and the likewise remote measuring system in a detachable manner. The measuring system forming part of the ophthalmological examination and/or treatment station comprises an optical system with a short-coherent radiation source (9) of the Michelson interferometer-type. An optically transparent and/or diffusive, reflecting object (1) can be introduced into the measuring arm (7) of said optical system and the reference arm (5) thereof has a wavelength variation unit (39) for modifying the runtime and at last two reflectors (31a, 31b) which produce a runtime difference.

Abstract: An optical arrangement of the Michelson interferometer type having a measuring arm for measuring optical properties of at least two mutually spaced regions in an optically transparent and/or diffusive object. A reference arm has a path length variation unit which generates a periodic change in path length for the radiation in the reference arm. Arranged in the measuring arm upstream of the object is a detour unit. The detour unit imparts a detour which is larger than at least one second measuring beam into at least one measuring beam. The detour unit selects a detour to be equal to a distance between regions to be measured in the object. Using the optical arrangement the object is irradiated with the aid of a number of measuring beams corresponding to the number of regions. In each case two measuring beams have an optical path difference which corresponds to a geometrical distance between two regions.

Abstract: In a method for photoablation on the cornea with a laser beam with the aid of which a multiplicity of consecutive partial ablation operations are undertaken, the thickness of the cornea is determined with the aid of a measuring device co-operating with a Michelson interferometer before and after each partial ablation operation. By using the thickness values determined, the measuring device guides the laser beam, with intensity values appropriately adjusted by it, over the cornea in a controlled fashion so as not to undershoot a prescribed cornea thickness while complying with a prescribed cornea profile. The measuring device operates with a Michelson interferometer with a center wavelength of the measuring beam source in the region of 1,310 nm, and a monomode fiber for this wavelength in the reference arm such that the optical path length in air in the measuring arm can be acceptably compensated.

Abstract: Provided are methods and compositions for the targeted delivery of therapeutic substances to specific cells and tissues. The methods and compositions of the present invention can be adapted for a wide variety of therapeutic applications that benefit from cell or tissue-specific delivery of drugs, thereby increasing the therapeutic index of drugs that otherwise produce systemic toxicity.