Patents by Inventor Rudolf Wank

Rudolf Wank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells
    Patent number: 9597384
    Abstract: The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: March 21, 2017
    Assignee: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
    Inventors: Dolores Schendel, Rudolf Wank
  • SEMI-ALLOGENIC ANTI-TUMOUR VACCINE WITH HLA HAPLO-IDENTICAL ANTIGEN-PRESENTING CELLS
    Publication number: 20160250308
    Abstract: The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
    Type: Application
    Filed: December 21, 2015
    Publication date: September 1, 2016
    Inventors: Dolores Schendel, Rudolf Wank
  • Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells
    Patent number: 9238063
    Abstract: The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: January 19, 2016
    Assignee: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundlheit und Umwelt (GmbH)
    Inventors: Dolores Schendel, Rudolf Wank
  • Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells
    Patent number: 8206701
    Abstract: The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: June 26, 2012
    Assignee: Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
    Inventors: Dolores Schendel, Rudolf Wank
  • SEMI-ALLOGENIC ANTI-TUMOUR VACCINE WITH HLA HAPLO-IDENTICAL ANTIGEN-PRESENTING CELLS
    Publication number: 20110182945
    Abstract: The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
    Type: Application
    Filed: February 15, 2011
    Publication date: July 28, 2011
    Inventors: Dolores SCHENDEL, Rudolf WANK
  • Use of stimulated peripheral-blood mononuclear cells for the treatment of cancerous diseases
    Patent number: 7871606
    Abstract: The invention relates to the use of peripheral-blood mononuclear cells that have been stimulated via cascade priming (CAPRI cells) for the purpose of providing an agent for the treatment of cancerous diseases. The CAPRI cells may also be administered in combination with CD3-activated cells.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: January 18, 2011
    Inventor: Rudolf Wank
  • Use of diuretics for treating swellings
    Publication number: 20050234107
    Abstract: The present invention relates to the use of a diuretic, especially a loop diuretic, for the treatment of local skin swellings. The invention further relates to pharmaceutical preparations of diuretics in topical form.
    Type: Application
    Filed: May 27, 2003
    Publication date: October 20, 2005
    Inventor: Rudolf Wank
  • Semi-allogenic anti-tumour vaccine with HLA haplo-identical antigen-presenting cells
    Publication number: 20050175596
    Abstract: The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases.
    Type: Application
    Filed: September 16, 2003
    Publication date: August 11, 2005
    Inventors: Dolores Schendel, Rudolf Wank
  • Use of stimulated peripheral-blood mononuclear cells for the treatment of cancerous diseases
    Publication number: 20040082065
    Abstract: The invention relates to the use of peripheral-blood mononuclear cells that have been stimulated via cascade priming (CAPRI cells) for the purpose of providing an agent for the treatment of cancerous diseases. The CAPRI cells may also be administered in combination with CD3-activated cells.
    Type: Application
    Filed: October 20, 2003
    Publication date: April 29, 2004
    Inventor: Rudolf Wank
  • Method for typing human leukocyte antigens
    Patent number: 4265873
    Abstract: A cellular method for typing lymphocyte defined human leukocyte antigens by utilizing human blood leukocytes which have been sensitized to proliferatively respond to the secondary stimulus of the leukocyte antigens to which they have been sensitized. The sensitization is accomplished by incubating, in vitro, in a mixed leukocyte culture, the leukocytes to be sensitized with leukocytes differing by only a single major histocompatibility complex haplotype or a single HLA-D antigenic determinant.
    Type: Grant
    Filed: July 3, 1978
    Date of Patent: May 5, 1981
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Michael J. Sheehy, Paul M. Sondel, Fritz H. Bach, Marilyn L. Bach, Rudolf Wank