Patents by Inventor Rudolph Juliano

Rudolph Juliano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecules that enhance the activity of oligonucleotides
    Patent number: 10266823
    Abstract: Methods of administering an oligonucleotide of interest into a cell in vitro or in vivo are described. In the methods, a small organic compound active agent is concurrently administered to the cell in an amount effective to increase the delivery of the oligonucleotide into the cell, and/or increase the activity of said oligonucleotide in the cell. Compositions useful for carrying out the method are also described.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: April 23, 2019
    Assignees: The University of North Carolina at Chapel Hill, Southern Research Institute
    Inventors: Rudolph Juliano, William P. Janzen, Joseph A. Maddry, Canhong Cao, Xin Ming, Bing Yang
  • SMALL MOLECULES THAT ENHANCE THE ACTIVITY OF OLIGONUCLEOTIDES
    Publication number: 20170130222
    Abstract: Methods of administering an oligonucleotide of interest into a cell in vitro or in vivo are described. In the methods, a small organic compound active agent is concurrently administered to the cell in an amount effective to increase the delivery of the oligonucleotide into the cell, and/or increase the activity of said oligonucleotide in the cell. Compositions useful for carrying out the method are also described.
    Type: Application
    Filed: June 26, 2015
    Publication date: May 11, 2017
    Inventors: Rudolph JULIANO, William P. JANZEN, Joseph A. MADDRY, Canhong CAO, Xin MING, Bing YANG
  • Selective killing of cancerous cells
    Publication number: 20060019922
    Abstract: The presently disclosed subject matter provides methods for selectively conferring toxicity on cancerous cells. Also provided are systems and kits that can be employed for performing the disclosed method.
    Type: Application
    Filed: July 14, 2005
    Publication date: January 26, 2006
    Applicant: The University of North Carolina
    Inventors: Rudolph Juliano, Dong Xu, Vidula Dixit