Patents by Inventor Rudy Juliano

Rudy Juliano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified Nucleosides for Rna Interference
    Publication number: 20080261905
    Abstract: The present invention relates to the use of modified nucleotides and single or double stranded oligonucleotides having at least one of said modified nucleotides for performing RNA interference. The modified nucleotides are selected from 6-membered ring containing nucleotides such as hexitol, altritol, O-substituted or O-alkylated altritol, cyclohexenyl, ribo-cyclohexenyl and O-substituted or O-alkylated ribo-cyclohexenyl nucleotides. The present invention also relates to novel modified nucleosides or nucleotides and to the use of the novel modified nucleosides and nucleotides in single or double stranded oligonucleotides for RNA interference, antisense therapy or other applications.
    Type: Application
    Filed: November 8, 2005
    Publication date: October 23, 2008
    Applicants: K.U. LEUVEN RESEARCH AND DEVELOPMENT, UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Piet Herdewijn, Arthur Van Aerschot, Jing Wang, Rudy Juliano