Patents by Inventor Rudy Laurent Maria Broeckx

Rudy Laurent Maria Broeckx has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing benzimidazole-type compounds
    Patent number: 6919459
    Abstract: The present invention relates to an improved process for the preparation of proton pump inhibitors of the benzimidazole-type such as rabeprazole, omeprazole, pantoprazole, lansoprazole and esome prazole, of general formula (1) by oxidation of the corresponding sulfide followed by extraction of the sulfone by-product with an aqueous alkaline solution at controlled pH.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: July 19, 2005
    Inventors: Rudy Laurent Maria Broeckx, Dirk De Smaele, Stefan Marcel Herman Leurs, Filip Verberckmoes
  • Process for the preparation of imidazole compounds
    Patent number: 6844439
    Abstract: A process for the preparation of 4-(3-chlorophenyl)-6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolinone which comprises reacting 6-(4-chlorobenzoyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone with a C6-8alkyllithium compound, 1-methylimidazole and a tri(C4-6alkyl)silyl halide to obtain better yields of the above product.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: January 18, 2005
    Assignee: Jansen Pharmaceutica, NV
    Inventors: Walter Ferdinand Maria Filliers, Rudy Laurent Maria Broeckx, Stefan Marcel Herman Leurs
  • Process for preparing benzimidazole-type compounds
    Publication number: 20040209918
    Abstract: The present invention relates to an improved process for the preparation of proton pump inhibitors of the benzimidazole-type such as rabeprazole, omeprazole, pantoprazole, lansoprazole and esome prazole, of general formula (1) by oxidation of the corresponding sulfide followed by extraction of the sulfone by-product with an acqueous alkaline solution at controlled pH.
    Type: Application
    Filed: June 4, 2004
    Publication date: October 21, 2004
    Inventors: Rudy Laurent Maria Broeckx, Dirk De Smaele, Stefan Marcel Herman Leurs, Filip Verberckmoes
  • Process for the preparation of imidazole compounds
    Publication number: 20040138256
    Abstract: A process for the preparation of 4-(3-chlorophenyl)-6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolinone which comprises reacting 6-(4-chlorobenzoyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone with a C6-8alkyllithium compound, 1-methylimidazole and a tri(C4-6alkyl)silyl halide to obtain better yields of the above product.
    Type: Application
    Filed: September 8, 2003
    Publication date: July 15, 2004
    Inventors: Walter Ferdinand Maria Fillers, Rudy Laurent Maria Broeckx, Stefan Marcel Herman Leurs