Abstract: Systems, methods and computer-readable media are disclosed for performing various filtering operations and selection processing on healthcare claim transaction data associated with a plurality of healthcare claim transactions. The filtering operations may include a first filtering operation to identify healthcare claim transactions reimbursed at a loss and a second filtering operation to further identify those transactions reimbursed at a MAC rate below cost. The selection processing may be performed to identify, from among the filtered healthcare claim transactions and based at least in part on one or more selection parameter thresholds, those transactions that are suitable candidates for MAC rate appropriateness review by a claims processor.