Abstract: Various implementations of implants and implant surfaces for clinical rehabilitation or enhancement of a patient, related systems, and computer programs and methods for the design and manufacturing of implants are disclosed. A macroscale shape, a microscale surface texture, and a nanoscale surface topography are overlaid to increase, condition, and thereby functionalize an implant surface. A thin-film coating and/or laser interferometry is utilized to overlay on a machined implant substrate a nanoscale surface topography. Manufacturing the macroscale shape and the microscale texture may be performed with an ultrashort pulsed laser system in separate process steps. The design of a dental implant may be assisted by a self-learning computer program product, based on trained coupled shape models including, for example, mesh-based statistical shape and orientation models.

Abstract: Various implementations of implants and implant surfaces for clinical rehabilitation or enhancement of a patient, related systems, and computer programs and methods for the design and manufacturing of implants are disclosed. A macroscale shape, a microscale surface texture, and a nanoscale surface topography are overlaid to increase, condition, and thereby functionalize an implant surface. A thin-film coating and/or laser interferometry is utilized to overlay on a machined implant substrate a nanoscale surface topography. Manufacturing the macroscale shape and the microscale texture may be performed with an ultrashort pulsed laser system in separate process steps. The design of a dental implant may be assisted by a self-learning computer program product, based on trained coupled shape models including, for example, mesh-based statistical shape and orientation models.

Abstract: Various implementations of implants and implant surfaces for clinical rehabilitation or enhancement of a patient, related systems, and computer programs and methods for the design and manufacturing of implants are disclosed. A macroscale shape, a microscale surface texture, and a nanoscale surface topography are overlaid to increase, condition, and thereby functionalize an implant surface. A thin-film coating and/or laser interferometry is utilized to overlay on a machined implant substrate a nanoscale surface topography. Manufacturing the macroscale shape and the microscale texture may be performed with an ultrashort pulsed laser system in separate process steps. The design of a dental implant may be assisted by a self-learning computer program product, based on trained coupled shape models including, for example, mesh-based statistical shape and orientation models.

Abstract: Various implementations of implants and implant surfaces for clinical rehabilitation or enhancement of a patient, related systems, and computer programs and methods for the design and manufacturing of implants are disclosed. A macroscale shape, a microscale surface texture, and a nanoscale surface topography are overlaid to increase, condition, and thereby functionalize an implant surface. A thin-film coating and/or laser interferometry is utilized to overlay on a machined implant substrate a nanoscale surface topography. Manufacturing the macroscale shape and the microscale texture may be performed with an ultrashort pulsed laser system in separate process steps. The design of a dental implant may be assisted by a self-learning computer program product, based on trained coupled shape models including, for example, mesh-based statistical shape and orientation models.

Abstract: Systems and methods for sterile delivery of prostheses that protect refined and/or conditioned surface properties and thereby reduce aging of surface properties in prostheses. An example of the system includes a partially custom-shaped holder that also serves as an insertion tool that holds a customized dental prosthesis in a pre-defined position inside a titanium container that is hermetically sealed. Container materials serve as a getter or catalyst with respect to the osseoconductive surface. An example of the method includes laser welding to hermetically seal a metal container as packaging for a prosthesis with a metal foil, and the sterilization of the packaged and sealed prosthesis with dry heat.

Abstract: Systems and methods are disclosed for sterile delivery of prostheses that protect refined and/or conditioned surface properties and thereby reduce aging of surface properties in prostheses. An example of the system includes a partially custom-shaped holder that also serves as an insertion tool that holds a customized dental prosthesis in a pre-defined position inside a titanium container that is hermetically sealed. Container materials serve as a getter or catalyst with respect to the osseoconductive surface. An example of the method includes laser welding to hermetically seal a metal container as packaging for a prosthesis with a metal foil, and the sterilization of the packaged and sealed prosthesis with dry heat.

Abstract: Various implementations, systems and methods are disclosed for continuous, near real-time, hands-off sampling of airborne particulate matter, and qualification and/or quantification of biomolecules in the sample representative for biologic or microbial contamination. The systems and methods may utilize an electrostatic precipitator for sampling the matter; and a measurement assembly configured to illuminate, excite, or breakdown the sampled matter by electromagnetic radiation, and to detect a spectrum, or one or more wavelength bands of the scatter emitted by the sample. In an exemplary implementation, a sputter deposition process is employed to configure the sample for an enhanced plasmon resonance. The measurement data may be transferred via wireless communication means for cloud storage and signal processing.

Abstract: Methods of manufacturing dental prosthesis/implants each to replace a non-functional natural tooth positioned in a jawbone of a specific pre-identified patient are provided. An example method includes the steps of receiving imaging data such as x-ray image data and surface scan data of a dental anatomy and/or a physical impression of the dental anatomy of a specific preidentified patient. The steps can also include forming a three-dimensional virtual model of at least portions of a non-functional natural tooth positioned in the jawbone of the specific pre-identified patient based on the imaging and surface scan data, virtually designing a dental implant based upon the virtual model, exporting the data describing the designed dental implant to a manufacturing machine, and custom manufacturing the dental implant for the specific patient.

Abstract: Methods of manufacturing dental prosthesis/implants each to replace a non-functional natural tooth positioned in a jawbone of a specific pre-identified patient are provided. An example method includes the steps of receiving imaging data such as x-ray image data and surface scan data of a dental anatomy and/or a physical impression of the dental anatomy of a specific preidentified patient. The steps can also include forming a three-dimensional virtual model of at least portions of a non-functional natural tooth positioned in the jawbone of the specific pre-identified patient based on the imaging and surface scan data, virtually designing a dental implant based upon the virtual model, exporting the data describing the designed dental implant to a manufacturing machine, and custom manufacturing the dental implant for the specific patient.

Abstract: A mouthpiece for inserting and securing a push-in-type dental implant in a jawbone bore hole or a natural extraction socket of a patient, related systems, and methods of designing and manufacturing a mouthpiece are disclosed. The mouthpiece can include a first interface to engage with an occlusal portion of the dental implant and at least a second interface to engage with occlusal surfaces of the opponent crowns so that the mouthpiece is operable to securely insert the dental implant into the jawbone bore hole or extraction socket of the patient when an upper jawbone and lower jawbone of a patient are brought together.

Abstract: Custom dental prosthesis or implants each individually designed and manufactured to replace nonfunctional natural teeth positioned in a jawbone of a specific pre-identified patient are provided. An example dental prosthesis/implant includes a dental implant body having a prosthesis interface formed therein to receive an occlusal-facing dental prosthesis component. The prosthesis interface has a custom three-dimensional surface shape positioned and formed to create a form locking fit with respect to the occlusal-facing dental prosthesis component when positioned thereon.

Abstract: Methods of manufacturing dental prosthesis/implants each to replace a non-functional natural tooth positioned in a jawbone of a specific pre-identified patient are provided. An example method includes the steps of receiving imaging data such as x-ray image data and surface scan data of a dental anatomy and/or a physical impression of the dental anatomy of a specific preidentified patient. The steps can also include forming a three-dimensional virtual model of at least portions of a non-functional natural tooth positioned in the jawbone of the specific pre-identified patient based on the imaging and surface scan data, virtually designing a dental implant based upon the virtual model, exporting the data describing the designed dental implant to a manufacturing machine, and custom manufacturing the dental implant for the specific patient.

Abstract: Methods of manufacturing dental prosthesis/implants each to replace a non-functional natural tooth positioned in a jawbone of a specific pre-identified patient are provided. An example method includes the steps of receiving imaging data such as x-ray image data and surface scan data of a dental anatomy and/or a physical impression of the dental anatomy of a specific preidentified patient. The steps can also include forming a three-dimensional virtual model of at least portions of a non-functional natural tooth positioned in the jawbone of the specific pre-identified patient based on the imaging and surface scan data, virtually designing a dental implant based upon the virtual model, exporting the data describing the designed dental implant to a manufacturing machine, and custom manufacturing the dental implant for the specific patient.

Abstract: An interface is provided for permitting a user to explore a collection of data. The data collection provides nodes as structural elements, and references which are assigned to the nodes and hold identifiers of other nodes. Multiple references can be assigned to each node, thus guiding a user of the system to multiple other nodes, and multiple references can hold the same address, so that multiple nodes can have references pointing to the same node. The interface allows visualizing the network created by the interconnection of the nodes on a display region. The interface also allows the user to intuitively navigate along the references in both directions of the references, so that the user can explore which nodes are referenced by a certain node, and also by which nodes a certain node is referenced.

Abstract: Integrated support devices for providing temporary primary stability to a dental prosthesis implant, each individually designed and manufactured for a specific pre-identify patient are also provided. An integrated support device can include a prosthesis interface member configured to connect to an abutment or reduced sized portion of a dental prosthesis/implant. The integrated support device also includes one or more bonding wings for connecting to the adjacent healthy teeth.

Abstract: A mouthpiece for inserting and securing a push-in-type dental implant in a jawbone bore hole or a natural extraction socket of a patient, related systems, and methods of designing and manufacturing a mouthpiece are disclosed. The mouthpiece can include a first interface to engage with an occlusal portion of the dental implant and at least a second interface to engage with occlusal surfaces of the opponent crowns so that the mouthpiece is operable to securely insert the dental implant into the jawbone bore hole or extraction socket of the patient when an upper jawbone and lower jawbone of a patient are brought together.

Abstract: A dental prosthesis to be integrated into a jaw bone cavity of a pre-identified patient. An example of a dental prosthesis includes a first manufactured portion having a surface shaped to substantially dimensionally conform three dimensionally to an undersized shape of the outer three-dimensional surface shape of a root of a tooth to be replaced, and a second manufactured portion shaped to substantially conform to the three-dimensional surface of a crown of the tooth. The outer surface of the root portion can include or be coated with a biocompatible material that is suitable to be integrated into the extraction socket and adopted by existing tissue forming the socket.

Abstract: Integrated support devices for providing temporary primary stability to a dental prosthesis implant, each individually designed and manufactured for a specific pre-identify patient are also provided. An integrated support device can include a prosthesis interface member configured to connect to an abutment or reduced sized portion of a dental prosthesis/implant. The integrated support device also includes one or more bonding wings for connecting to the adjacent healthy teeth.

Abstract: An interface is provided for permitting a user to explore a collection of data. The data collection provides nodes as structural elements, and references which are assigned to the nodes and hold identifiers of other nodes. Multiple references can be assigned to each node, thus guiding a user of the system to multiple other nodes, and multiple references can hold the same address, so that multiple nodes can have references pointing to the same node. The interface allows visualizing the network created by the interconnection of the nodes on a display region. The interface also allows the user to intuitively navigate along the references in both directions of the references, so that the user can explore which nodes are referenced by a certain node, and also by which nodes a certain node is referenced.

Abstract: Custom dental prosthesis or implants each individually designed and manufactured to replace nonfunctional natural teeth positioned in a jawbone of a specific pre-identified patient are provided. An example dental prosthesis/implant includes a dental implant body having a prosthesis interface formed therein to receive an occlusally-facing dental prosthesis component. The prosthesis interface has a custom three-dimensional surface shape positioned and formed to create a form locking fit with respect to the occlusally-facing dental prosthesis component when positioned thereon.